From HPO
Portal hypertension- MedGen UID:
- 9375
- •Concept ID:
- C0020541
- •
- Disease or Syndrome
Increased pressure in the portal vein.
Cholestasis- MedGen UID:
- 925
- •Concept ID:
- C0008370
- •
- Disease or Syndrome
Impairment of bile flow due to obstruction in bile ducts.
Esophageal varix- MedGen UID:
- 5027
- •Concept ID:
- C0014867
- •
- Disease or Syndrome
Extreme dilation of the submucusoal veins in the lower portion of the esophagus.
Hepatomegaly- MedGen UID:
- 42428
- •Concept ID:
- C0019209
- •
- Finding
Abnormally increased size of the liver.
Jaundice- MedGen UID:
- 43987
- •Concept ID:
- C0022346
- •
- Sign or Symptom
Yellow pigmentation of the skin due to bilirubin, which in turn is the result of increased bilirubin concentration in the bloodstream.
Cirrhosis of liver- MedGen UID:
- 7368
- •Concept ID:
- C0023890
- •
- Disease or Syndrome
A chronic disorder of the liver in which liver tissue becomes scarred and is partially replaced by regenerative nodules and fibrotic tissue resulting in loss of liver function.
Hepatic fibrosis- MedGen UID:
- 116093
- •Concept ID:
- C0239946
- •
- Disease or Syndrome
The presence of excessive fibrous connective tissue in the liver. Fibrosis is a reparative or reactive process.
Bile duct proliferation- MedGen UID:
- 120603
- •Concept ID:
- C0267818
- •
- Disease or Syndrome
Proliferative changes of the bile ducts.
Hepatic bridging fibrosis- MedGen UID:
- 868315
- •Concept ID:
- C4022709
- •
- Disease or Syndrome
Hepatic fibrosis that reaches from a portal area to another portal area.
Sclerosing cholangitis- MedGen UID:
- 3036
- •Concept ID:
- C0008313
- •
- Disease or Syndrome
Cholangitis associated with evident ductal fibrosis that develops as a consequence of long-standing bile duct inflammatory, obstruction, or ischemic injury; it can be obliterative or nonobliterative.
Hypercholesterolemia- MedGen UID:
- 5687
- •Concept ID:
- C0020443
- •
- Disease or Syndrome
An increased concentration of cholesterol in the blood.
Elevated circulating aspartate aminotransferase concentration- MedGen UID:
- 57497
- •Concept ID:
- C0151904
- •
- Finding
The concentration of aspartate aminotransferase (AST) in the blood circulation is above the upper limit of normal.
Elevated circulating alanine aminotransferase concentration- MedGen UID:
- 57740
- •Concept ID:
- C0151905
- •
- Finding
An abnormally high concentration in the circulation of alanine aminotransferase (ALT).
Elevated circulating alpha-fetoprotein concentration- MedGen UID:
- 65916
- •Concept ID:
- C0235971
- •
- Finding
Concentration of alpha-fetoprotein in the blood circulation above the upper limit of normal.
Conjugated hyperbilirubinemia- MedGen UID:
- 82787
- •Concept ID:
- C0268307
- •
- Disease or Syndrome
Abnormally high level of conjugated bilirubin in the blood.
Elevated circulating alkaline phosphatase concentration- MedGen UID:
- 727252
- •Concept ID:
- C1314665
- •
- Finding
Abnormally increased serum levels of alkaline phosphatase activity.
Increased serum bile acid concentration- MedGen UID:
- 868605
- •Concept ID:
- C4023004
- •
- Finding
An increase in the concentration of bile acid in the blood.
Elevated gamma-glutamyltransferase level- MedGen UID:
- 1370086
- •Concept ID:
- C4476869
- •
- Finding
Increased level of the enzyme gamma-glutamyltransferase (GGT). GGT is mainly present in kidney, liver, and pancreatic cells, but small amounts are present in other tissues.
Pruritus- MedGen UID:
- 19534
- •Concept ID:
- C0033774
- •
- Sign or Symptom
Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased disposition to experience pruritus.
- Abnormality of metabolism/homeostasis
- Abnormality of the cardiovascular system
- Abnormality of the digestive system
- Abnormality of the immune system
- Abnormality of the integument