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Uterine Corpus Inflammatory Myofibroblastic Tumor

MedGen UID:
1792898
•Concept ID:
C5556457
•
Neoplastic Process

Definition

A rare inflammatory myofibroblastic tumor that arises from the uterine corpus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUterine Corpus Inflammatory Myofibroblastic Tumor

Recent clinical studies

Etiology

ALK Immunoexpression is Specific for Inflammatory Myofibroblastic Tumor Among Vulvovaginal Mesenchymal Neoplasms.
Bowman CJ, Medeiros F, Fadare O, Sangoi AR, Horvai AE, Devine WP, McCluggage WG, Rabban JT
Int J Gynecol Pathol 2023 Jan 1;42(1):1-10. Epub 2022 Feb 18 doi: 10.1097/PGP.0000000000000858. PMID: 35180768

Diagnosis

ALK Immunoexpression is Specific for Inflammatory Myofibroblastic Tumor Among Vulvovaginal Mesenchymal Neoplasms.
Bowman CJ, Medeiros F, Fadare O, Sangoi AR, Horvai AE, Devine WP, McCluggage WG, Rabban JT
Int J Gynecol Pathol 2023 Jan 1;42(1):1-10. Epub 2022 Feb 18 doi: 10.1097/PGP.0000000000000858. PMID: 35180768
NTRK-Fusion Sarcoma of the Uterine Cervix: Report of 2 Cases With Comparative Clinicopathologic Features.
Nilforoushan N, Wethington SL, Nonogaki H, Gross J, Vang R, Xing D
Int J Gynecol Pathol 2022 Nov 1;41(6):642-648. Epub 2021 Oct 29 doi: 10.1097/PGP.0000000000000834. PMID: 34723848Free PMC Article
ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
CT and MRI of early intrauterine pregnancy.
Shin DS, Poder L, Courtier J, Naeger DM, Westphalen AC, Coakley FV
AJR Am J Roentgenol 2011 Feb;196(2):325-30. doi: 10.2214/AJR.09.3723. PMID: 21257883
Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change.
Shintaku M, Fukushima A
Pathol Int 2006 Oct;56(10):625-8. doi: 10.1111/j.1440-1827.2006.02018.x. PMID: 16984620

Therapy

CT and MRI of early intrauterine pregnancy.
Shin DS, Poder L, Courtier J, Naeger DM, Westphalen AC, Coakley FV
AJR Am J Roentgenol 2011 Feb;196(2):325-30. doi: 10.2214/AJR.09.3723. PMID: 21257883

Prognosis

ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720

Clinical prediction guides

A Novel CASC15-ALK and TFG-ROS1 Fusion Observed in Uterine Inflammatory Myofibroblastic Tumor.
Chang B, Wang Z, Ren M, Yao Q, Zhao L, Zhou X
Int J Gynecol Pathol 2023 Sep 1;42(5):451-459. Epub 2022 Dec 1 doi: 10.1097/PGP.0000000000000926. PMID: 36730016
ALK Is a Specific Diagnostic Marker for Inflammatory Myofibroblastic Tumor of the Uterus.
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change.
Shintaku M, Fukushima A
Pathol Int 2006 Oct;56(10):625-8. doi: 10.1111/j.1440-1827.2006.02018.x. PMID: 16984620

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