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Peritoneal Low Grade Endometrioid Stromal Sarcoma

MedGen UID:
1792214
•Concept ID:
C5555773
•
Neoplastic Process
Synonym: Peritoneal Endometrioid Stromal Sarcoma

Definition

A very rare sarcoma that arises from the peritoneum and is characterized by the presence of cells that resemble endometrial stromal cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeritoneal Low Grade Endometrioid Stromal Sarcoma

Professional guidelines

PubMed

Annual report of the committee on gynecologic oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2021 and annual treatment report for 2016.
Kajiyama H, Tamauchi S, Takahashi F, Kawana K; Board members of the 2023 Committee on Gynecologic Oncology of the Japan Society of Obstetrics and Gynecology
J Obstet Gynaecol Res 2025 Jan;51(1):e16168. Epub 2024 Nov 25 doi: 10.1111/jog.16168. PMID: 39587792
Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2017 and annual treatment report for 2012.
Nagase S, Ohta T, Takahashi F, Yaegashi N; Board members of the 2020 Committee on Gynecologic Oncology of the Japan Society of Obstetrics and Gynecology
J Obstet Gynaecol Res 2021 May;47(5):1631-1642. Epub 2021 Feb 25 doi: 10.1111/jog.14724. PMID: 33631867
Extrauterine Spread, Adjuvant Treatment, and Prognosis in Noninvasive Uterine Papillary Serous Carcinoma of the Endometrium: A Retrospective Multicenter Study.
Boyraz G, Salman MC, Basaran D, Ozgul N, Turan T, Turkmen O, Kimyon GC, Ozkan NT, Cagan M, Gungor T, Meydanli MM, Gungorduk K, Gulseren V, Sanci M, Yuce K
Int J Gynecol Cancer 2017 Jan;27(1):102-108. doi: 10.1097/IGC.0000000000000838. PMID: 27668395

Recent clinical studies

Etiology

Correlation between malignant peritoneal cytology and survival in patients with uterine leiomyosarcoma and endometrial stromal sarcoma.
Du J, Hu D, Xing Y, He R, Cheng Y, Li H, Liu C, Liang X, Yang Y
Int J Gynecol Cancer 2024 Jan 5;34(1):58-65. doi: 10.1136/ijgc-2023-004792. PMID: 37821125
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
Low-Grade Endometrial Stromal Sarcoma Diagnosed 8 Years After Hysterectomy With Morcellation.
Sanneh A, Murdock T, Wethington SL, Fader AN, Xing D, Beavis AL
Obstet Gynecol 2020 Aug;136(2):365-368. doi: 10.1097/AOG.0000000000003908. PMID: 32649495
Prognostic factors of synchronous endometrial and ovarian endometrioid carcinoma.
Yoneoka Y, Yoshida H, Ishikawa M, Shimizu H, Uehara T, Murakami T, Kato T
J Gynecol Oncol 2019 Jan;30(1):e7. Epub 2018 Sep 17 doi: 10.3802/jgo.2019.30.e7. PMID: 30479091Free PMC Article
Long-term medroxyprogesterone acetate therapy for low-grade endometrial stromal sarcoma.
Mizuno M, Yatabe Y, Nawa A, Nakanishi T
Int J Clin Oncol 2012 Aug;17(4):348-54. Epub 2011 Aug 10 doi: 10.1007/s10147-011-0299-y. PMID: 21830086

Diagnosis

Low-grade extrauterine endometrial stromal sarcoma of the peritoneum: A case report and literature review.
Gorostiaga I, Perez-Rodriguez A, Gómez-Mateo MC, Cuadra-Cestafe M, Sagasta A
Rev Esp Patol 2021 Jul-Sep;54(3):201-205. Epub 2020 Sep 3 doi: 10.1016/j.patol.2020.06.009. PMID: 34175034
An uncommon response to metronomic therapy in a heavily pretreated patient with metastatic carcinosarcoma: a case report.
Gagliato Dde M, Linck RD, Bezerra RO, Souto M, Lopes GL, Baiocchi G, Mano MS
J Med Case Rep 2016 Mar 14;10:60. doi: 10.1186/s13256-016-0837-3. PMID: 26971567Free PMC Article
Extragenital endometrial stromal sarcoma arising in endometriosis.
Alcázar JL, Guerriero S, Ajossa S, Parodo G, Piras B, Peiretti M, Jurado M, Idoate MÁ
Gynecol Obstet Invest 2012;73(4):265-71. Epub 2012 Apr 24 doi: 10.1159/000336522. PMID: 22538201
Pathologic quiz case: a 46-year-old woman with 1-day history of abdominal pain and intestinal obstruction. Extrauterine low-grade endometrial stromal sarcoma.
Rojas H, Wang J, Chase D, Wang J
Arch Pathol Lab Med 2005 Feb;129(2):e44-6. doi: 10.5858/2005-129-e44-PQC. PMID: 15679447
Sonographic, CT, and MRI findings of endometrial stromal sarcoma located in the myometrium and associated with peritoneal inclusion cyst.
Toprak U, Paşaoğlu E, Karademir MA, Gülbay M
AJR Am J Roentgenol 2004 Jun;182(6):1531-3. doi: 10.2214/ajr.182.6.1821531. PMID: 15150002

Therapy

Correlation between malignant peritoneal cytology and survival in patients with uterine leiomyosarcoma and endometrial stromal sarcoma.
Du J, Hu D, Xing Y, He R, Cheng Y, Li H, Liu C, Liang X, Yang Y
Int J Gynecol Cancer 2024 Jan 5;34(1):58-65. doi: 10.1136/ijgc-2023-004792. PMID: 37821125
Recurrence after fertility-preserving surgery for low-grade endometrial stromal sarcoma.
Chin TH, Lin G, Wu RC, Lai CH
J Obstet Gynaecol Res 2018 Sep;44(9):1836-1842. Epub 2018 Jul 5 doi: 10.1111/jog.13695. PMID: 29974555
An uncommon response to metronomic therapy in a heavily pretreated patient with metastatic carcinosarcoma: a case report.
Gagliato Dde M, Linck RD, Bezerra RO, Souto M, Lopes GL, Baiocchi G, Mano MS
J Med Case Rep 2016 Mar 14;10:60. doi: 10.1186/s13256-016-0837-3. PMID: 26971567Free PMC Article
Long-term medroxyprogesterone acetate therapy for low-grade endometrial stromal sarcoma.
Mizuno M, Yatabe Y, Nawa A, Nakanishi T
Int J Clin Oncol 2012 Aug;17(4):348-54. Epub 2011 Aug 10 doi: 10.1007/s10147-011-0299-y. PMID: 21830086
Megestrol acetate therapy for advanced low-grade endometrial stromal sarcoma.
Lim MC, Lee S, Seo SS
Onkologie 2010;33(5):260-2. Epub 2010 Apr 21 doi: 10.1159/000305661. PMID: 20502061

Prognosis

Correlation between malignant peritoneal cytology and survival in patients with uterine leiomyosarcoma and endometrial stromal sarcoma.
Du J, Hu D, Xing Y, He R, Cheng Y, Li H, Liu C, Liang X, Yang Y
Int J Gynecol Cancer 2024 Jan 5;34(1):58-65. doi: 10.1136/ijgc-2023-004792. PMID: 37821125
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
Primary ovarian high-grade endometrial stromal sarcoma: a case report.
Lee JS, Lee D, Lee J, Han MH, Hong DG, Lee HJ
J Med Case Rep 2021 Aug 3;15(1):387. doi: 10.1186/s13256-021-02986-0. PMID: 34340706Free PMC Article
Endometrioid stromal sarcoma: a clinicopathologic study of 63 cases.
Masand RP, Euscher ED, Deavers MT, Malpica A
Am J Surg Pathol 2013 Nov;37(11):1635-47. doi: 10.1097/PAS.0000000000000083. PMID: 24121169
Extragenital endometrial stromal sarcoma arising in endometriosis.
Alcázar JL, Guerriero S, Ajossa S, Parodo G, Piras B, Peiretti M, Jurado M, Idoate MÁ
Gynecol Obstet Invest 2012;73(4):265-71. Epub 2012 Apr 24 doi: 10.1159/000336522. PMID: 22538201

Clinical prediction guides

Correlation between malignant peritoneal cytology and survival in patients with uterine leiomyosarcoma and endometrial stromal sarcoma.
Du J, Hu D, Xing Y, He R, Cheng Y, Li H, Liu C, Liang X, Yang Y
Int J Gynecol Cancer 2024 Jan 5;34(1):58-65. doi: 10.1136/ijgc-2023-004792. PMID: 37821125
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
Prognostic factors of synchronous endometrial and ovarian endometrioid carcinoma.
Yoneoka Y, Yoshida H, Ishikawa M, Shimizu H, Uehara T, Murakami T, Kato T
J Gynecol Oncol 2019 Jan;30(1):e7. Epub 2018 Sep 17 doi: 10.3802/jgo.2019.30.e7. PMID: 30479091Free PMC Article
Endometrioid stromal sarcoma: a clinicopathologic study of 63 cases.
Masand RP, Euscher ED, Deavers MT, Malpica A
Am J Surg Pathol 2013 Nov;37(11):1635-47. doi: 10.1097/PAS.0000000000000083. PMID: 24121169
Peritoneal washing cytology of disseminated low grade endometrial stromal sarcoma: a case report.
Lim BJ, Choi SY, Kang DY, Suh KS
Acta Cytol 2009 Sep-Oct;53(5):587-90. doi: 10.1159/000325390. PMID: 19798890

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