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Breast Periductal Stromal Tumor

MedGen UID:
1791978
Concept ID:
C5555537
Neoplastic Process
Synonym: Periductal Stromal Tumor

Definition

A rare, low-grade malignant stromal tumor that arises from the breast. It is characterized by the proliferation of atypical stromal spindle cells that surround benign tubules and ducts in a pericanalicular pattern. Mitotic activity is present. The tumor has a multinodular and infiltrative growth pattern and lacks the leaf-like architecture of phyllodes tumor. Wide excision with negative margins is the treatment of choice. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Periductal Stromal Tumor

Recent clinical studies

Diagnosis

Anderson B, Marotti JD, Lefferts JA, Muller KE
Int J Surg Pathol 2023 Dec;31(8):1626-1631. Epub 2023 Feb 23 doi: 10.1177/10668969231157306. PMID: 36823780Free PMC Article

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