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Conjunctival Stromal Tumor

MedGen UID:
1783272
•Concept ID:
C5446571
•
Neoplastic Process

Definition

A rare benign stromal tumor that arises from the bulbar conjunctiva. It is characterized by the presence of myxoid/collagenous stroma, spindle-shaped cells, pseudonuclear inclusions, and multinucleated cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVConjunctival Stromal Tumor

Professional guidelines

PubMed

Histopathology-guided management of ocular surface squamous neoplasia with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy.
Rao R, Honavar SG, Lahane S, Mulay K, Reddy VP
Br J Ophthalmol 2023 May;107(5):621-626. Epub 2021 Nov 29 doi: 10.1136/bjophthalmol-2021-319201. PMID: 34844918
Management of diffuse ocular surface squamous neoplasia: efficacy and complications of topical chemotherapy.
Rudkin AK, Dempster L, Muecke JS
Clin Exp Ophthalmol 2015 Jan-Feb;43(1):20-5. Epub 2014 Sep 9 doi: 10.1111/ceo.12377. PMID: 24995542
Plaque brachytherapy for the management of ocular surface malignancies with corneoscleral invasion.
Walsh-Conway N, Conway RM
Clin Exp Ophthalmol 2009 Aug;37(6):577-83. doi: 10.1111/j.1442-9071.2009.02092.x. PMID: 19702707

Recent clinical studies

Etiology

Conjunctival Stromal Tumor: Report of 2 New Cases and Review of the Literature.
Lam J, Ang A, Vermeulen T, Ardakani NM
Int J Surg Pathol 2021 May;29(3):337-342. Epub 2020 Jul 29 doi: 10.1177/1066896920945783. PMID: 32723103
Conjunctival Myxoid Lesions: Clinical-Pathologic Multiparametric Analysis, Including Molecular Genetics (An American Ophthalmological Society Thesis).
Milman T, Salomao DR, Ida CM, Capiz Correa DR, Grossniklaus HE, Zhang Q, Hamershock RA, Shields C, Shields JA, Raber I, Rapuano CJ, Patel R, Eagle RC Jr
Am J Ophthalmol 2019 Sep;205:115-131. Epub 2019 May 10 doi: 10.1016/j.ajo.2019.04.027. PMID: 31078543
Conjunctival stromal tumor: report of 4 cases.
Herwig MC, Wells JR, Grossniklaus HE
Ophthalmology 2012 Apr;119(4):682-7. Epub 2011 Dec 24 doi: 10.1016/j.ophtha.2011.09.024. PMID: 22200094Free PMC Article

Diagnosis

Conjunctival Stromal Tumor: Report of 2 New Cases and Review of the Literature.
Lam J, Ang A, Vermeulen T, Ardakani NM
Int J Surg Pathol 2021 May;29(3):337-342. Epub 2020 Jul 29 doi: 10.1177/1066896920945783. PMID: 32723103
Conjunctival Myxoid Lesions: Clinical-Pathologic Multiparametric Analysis, Including Molecular Genetics (An American Ophthalmological Society Thesis).
Milman T, Salomao DR, Ida CM, Capiz Correa DR, Grossniklaus HE, Zhang Q, Hamershock RA, Shields C, Shields JA, Raber I, Rapuano CJ, Patel R, Eagle RC Jr
Am J Ophthalmol 2019 Sep;205:115-131. Epub 2019 May 10 doi: 10.1016/j.ajo.2019.04.027. PMID: 31078543
Conjunctival Stromal Tumor.
Greenberg EL, Espana EM, Margo CE
Ophthalmology 2018 Jan;125(1):88. doi: 10.1016/j.ophtha.2017.10.002. PMID: 29268870
Conjunctival Stromal Tumor: Expansion of Findings in a Newly Described Entity.
Auw-Haedrich C, Danielewicz KD, Mendoza PR, Reinhard T, Grossniklaus HE
Ophthalmology 2016 May;123(5):1166-7. Epub 2016 Jan 8 doi: 10.1016/j.ophtha.2015.11.027. PMID: 26778331Free PMC Article

Prognosis

Conjunctival Myxoid Lesions: Clinical-Pathologic Multiparametric Analysis, Including Molecular Genetics (An American Ophthalmological Society Thesis).
Milman T, Salomao DR, Ida CM, Capiz Correa DR, Grossniklaus HE, Zhang Q, Hamershock RA, Shields C, Shields JA, Raber I, Rapuano CJ, Patel R, Eagle RC Jr
Am J Ophthalmol 2019 Sep;205:115-131. Epub 2019 May 10 doi: 10.1016/j.ajo.2019.04.027. PMID: 31078543
Conjunctival stromal tumor: report of 4 cases.
Herwig MC, Wells JR, Grossniklaus HE
Ophthalmology 2012 Apr;119(4):682-7. Epub 2011 Dec 24 doi: 10.1016/j.ophtha.2011.09.024. PMID: 22200094Free PMC Article

Clinical prediction guides

Conjunctival stromal tumor: report of 4 cases.
Herwig MC, Wells JR, Grossniklaus HE
Ophthalmology 2012 Apr;119(4):682-7. Epub 2011 Dec 24 doi: 10.1016/j.ophtha.2011.09.024. PMID: 22200094Free PMC Article

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