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COVID-19 Dermatologic Manifestation

MedGen UID:
1754160
•Concept ID:
C5420366
•
Sign or Symptom
Synonym: COVID-19 Skin Manifestation

Definition

A skin abnormality that is associated with SARS-CoV-2 infection (COVID-19). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19 Dermatologic Manifestation

Professional guidelines

PubMed

Management of systemic lupus erythematosus: a systematic literature review informing the 2023 update of the EULAR recommendations.
Kostopoulou M, Mukhtyar CB, Bertsias G, Boumpas DT, Fanouriakis A
Ann Rheum Dis 2024 Oct 21;83(11):1489-1501. doi: 10.1136/ard-2023-225319. PMID: 38777375Free PMC Article
Differential Diagnosis of Lesions.
Milo RB
Adv Emerg Nurs J 2022 Jan-Mar 01;44(1):23-28. doi: 10.1097/TME.0000000000000388. PMID: 35089277
Identification, Mechanism, and Treatment of Skin Lesions in COVID-19: A Review.
Fernández-Lázaro D, Garrosa M
Viruses 2021 Sep 24;13(10) doi: 10.3390/v13101916. PMID: 34696346Free PMC Article

Recent clinical studies

Etiology

Coronavirus Disease 2019 and Race in Dermatology.
Desai SR, McMichael AJ, Khanna R
Dermatol Clin 2021 Oct;39(4):569-574. Epub 2021 Jul 29 doi: 10.1016/j.det.2021.05.003. PMID: 34556246Free PMC Article
Skin manifestations associated with systemic diseases - Part I.
Sampaio AL, Bressan AL, Vasconcelos BN, Gripp AC
An Bras Dermatol 2021 Nov-Dec;96(6):655-671. Epub 2021 Sep 17 doi: 10.1016/j.abd.2021.02.008. PMID: 34544638Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives.
Genovese G, Moltrasio C, Berti E, Marzano AV
Dermatology 2021;237(1):1-12. Epub 2020 Nov 24 doi: 10.1159/000512932. PMID: 33232965Free PMC Article
Covid-19 pandemic and the skin.
Drenovska K, Schmidt E, Vassileva S
Int J Dermatol 2020 Nov;59(11):1312-1319. Epub 2020 Sep 21 doi: 10.1111/ijd.15189. PMID: 32954488Free PMC Article

Diagnosis

Scalp dysesthesia: a neuropathic phenomenon.
Ju T, Vander Does A, Yosipovitch G
J Eur Acad Dermatol Venereol 2022 Jun;36(6):790-796. Epub 2022 Feb 14 doi: 10.1111/jdv.17985. PMID: 35122352
Coronavirus Disease 2019 and Race in Dermatology.
Desai SR, McMichael AJ, Khanna R
Dermatol Clin 2021 Oct;39(4):569-574. Epub 2021 Jul 29 doi: 10.1016/j.det.2021.05.003. PMID: 34556246Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Cutaneous manifestations of viral outbreaks.
Bothra A, Maheswari A, Singh M, Pawar M, Jodhani K
Australas J Dermatol 2021 Feb;62(1):27-36. Epub 2020 Sep 8 doi: 10.1111/ajd.13421. PMID: 32895964
Extrapulmonary manifestations of COVID-19.
Gupta A, Madhavan MV, Sehgal K, Nair N, Mahajan S, Sehrawat TS, Bikdeli B, Ahluwalia N, Ausiello JC, Wan EY, Freedberg DE, Kirtane AJ, Parikh SA, Maurer MS, Nordvig AS, Accili D, Bathon JM, Mohan S, Bauer KA, Leon MB, Krumholz HM, Uriel N, Mehra MR, Elkind MSV, Stone GW, Schwartz A, Ho DD, Bilezikian JP, Landry DW
Nat Med 2020 Jul;26(7):1017-1032. Epub 2020 Jul 10 doi: 10.1038/s41591-020-0968-3. PMID: 32651579

Therapy

Axial spondylarthritis following COVID-19 infection.
Gopalarathinam R, Nawimana S, Nune A
BMJ Case Rep 2023 May 25;16(5) doi: 10.1136/bcr-2022-252985. PMID: 37230746Free PMC Article
Dermatopathology of COVID-19 infection and vaccination.
Fernández-Figueras MT
Pathologie (Heidelb) 2022 Aug;43(Suppl 1):114-118. Epub 2022 Oct 5 doi: 10.1007/s00292-022-01126-9. PMID: 36197514Free PMC Article
Kawasaki Disease with Peripheral and Facial Gangrene: A Case report and review of literature.
Madan D, Maheshwari A, Mahto D, Mendiratta V, Sharma S
Trop Doct 2022 Jul;52(3):449-452. Epub 2022 Mar 29 doi: 10.1177/00494755221081598. PMID: 35345947
COVID-19, microthromboses, inflammation, and platelet activating factor.
Demopoulos C, Antonopoulou S, Theoharides TC
Biofactors 2020 Nov;46(6):927-933. Epub 2020 Dec 9 doi: 10.1002/biof.1696. PMID: 33296106
COVID-19: An overview for dermatologists.
Sanghvi AR
Int J Dermatol 2020 Dec;59(12):1437-1449. Epub 2020 Oct 27 doi: 10.1111/ijd.15257. PMID: 33107038

Prognosis

COVID-19 and cutaneous manifestations: A review of the published literature.
Martora F, Villani A, Fabbrocini G, Battista T
J Cosmet Dermatol 2023 Jan;22(1):4-10. Epub 2022 Nov 7 doi: 10.1111/jocd.15477. PMID: 36342945Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Covid-19 pandemic and the skin.
Drenovska K, Schmidt E, Vassileva S
Int J Dermatol 2020 Nov;59(11):1312-1319. Epub 2020 Sep 21 doi: 10.1111/ijd.15189. PMID: 32954488Free PMC Article
Dermatologic manifestations and complications of COVID-19.
Gottlieb M, Long B
Am J Emerg Med 2020 Sep;38(9):1715-1721. Epub 2020 Jun 6 doi: 10.1016/j.ajem.2020.06.011. PMID: 32731141Free PMC Article
Clinical characteristics of dermatologic manifestations of COVID-19 infection: case series of 15 patients, review of literature, and proposed etiological classification.
Potekaev NN, Zhukova OV, Protsenko DN, Demina OM, Khlystova EA, Bogin V
Int J Dermatol 2020 Aug;59(8):1000-1009. Epub 2020 Jul 3 doi: 10.1111/ijd.15030. PMID: 32621287Free PMC Article

Clinical prediction guides

Levamisole-induced and COVID-19-induced retiform purpura: two overlapping, emerging clinical syndromes.
Keim CK, Schwartz RA, Kapila R
Arch Dermatol Res 2023 Mar;315(2):265-273. Epub 2021 Nov 22 doi: 10.1007/s00403-021-02303-1. PMID: 34807290Free PMC Article
Pathobiology of Cutaneous Manifestations Associated with COVID-19 and Their Management.
Masood W, Ahmad S, Khan NA, Shakir A, Rokni GR, Gold MH, Cockerell CJ, Schwartz RA, Goldust M
Viruses 2022 Sep 6;14(9) doi: 10.3390/v14091972. PMID: 36146777Free PMC Article
A dermatologic perspective on multisystem inflammatory syndrome in children.
Naka F, Melnick L, Gorelik M, Morel KD
Clin Dermatol 2021 Mar-Apr;39(2):337-343. Epub 2020 Nov 26 doi: 10.1016/j.clindermatol.2020.11.005. PMID: 34272033Free PMC Article
COVID-19: The experience from Italy.
Recalcati S, Gianotti R, Fantini F
Clin Dermatol 2021 Jan-Feb;39(1):12-22. Epub 2020 Dec 17 doi: 10.1016/j.clindermatol.2020.12.008. PMID: 33972039Free PMC Article
Non-respiratory presentations of COVID-19, a clinical review.
AlSamman M, Caggiula A, Ganguli S, Misak M, Pourmand A
Am J Emerg Med 2020 Nov;38(11):2444-2454. Epub 2020 Sep 24 doi: 10.1016/j.ajem.2020.09.054. PMID: 33039218Free PMC Article

Recent systematic reviews

Management of systemic lupus erythematosus: a systematic literature review informing the 2023 update of the EULAR recommendations.
Kostopoulou M, Mukhtyar CB, Bertsias G, Boumpas DT, Fanouriakis A
Ann Rheum Dis 2024 Oct 21;83(11):1489-1501. doi: 10.1136/ard-2023-225319. PMID: 38777375Free PMC Article
Cutaneous adverse reactions following COVID-19 vaccinations: A systematic review and meta-analysis.
Shafie'ei M, Jamali M, Akbari Z, Sarvipour N, Ahmadzade M, Ahramiyanpour N
J Cosmet Dermatol 2022 Sep;21(9):3636-3650. Epub 2022 Aug 1 doi: 10.1111/jocd.15261. PMID: 35861631Free PMC Article
COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review.
Erbaş GS, Botsali A, Erden N, Arı C, Taşkın B, Alper S, Vural S
Int J Dermatol 2022 Jan;61(1):20-32. Epub 2021 Sep 22 doi: 10.1111/ijd.15889. PMID: 34549816Free PMC Article
Severe and life-threatening COVID-19-related mucocutaneous eruptions: A systematic review.
Mashayekhi F, Seirafianpour F, Pour Mohammad A, Goodarzi A
Int J Clin Pract 2021 Dec;75(12):e14720. Epub 2021 Sep 28 doi: 10.1111/ijcp.14720. PMID: 34411409Free PMC Article
Clinical manifestations of COVID-19 in the general population: systematic review.
da Rosa Mesquita R, Francelino Silva Junior LC, Santos Santana FM, Farias de Oliveira T, Campos Alcântara R, Monteiro Arnozo G, Rodrigues da Silva Filho E, Galdino Dos Santos AG, Oliveira da Cunha EJ, Salgueiro de Aquino SH, Freire de Souza CD
Wien Klin Wochenschr 2021 Apr;133(7-8):377-382. Epub 2020 Nov 26 doi: 10.1007/s00508-020-01760-4. PMID: 33242148Free PMC Article

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