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Digestive System Leiomyosarcoma

MedGen UID:
1748737
•Concept ID:
C5421284
•
Neoplastic Process

Definition

A leiomyosarcoma arising from an anatomic site in the digestive system. [from NCI]

Professional guidelines

PubMed

Effect of Double-Balloon Enteroscopy on Diagnosis and Treatment of Small-Bowel Diseases.
Tang L, Huang LY, Cui J, Wu CR
Chin Med J (Engl) 2018 Jun 5;131(11):1321-1326. doi: 10.4103/0366-6999.232802. PMID: 29786046Free PMC Article
Gastrointestinal Stromal Tumors - Diagnosis and Surgical Treatment.
Alecu L, Tulin A, Enciu O, Bărbulescu M, Ursuţ B, Obrocea F
Chirurgia (Bucur) 2015 Nov-Dec;110(6):525-9. PMID: 26713826
Hypomagnesemia in general hypothermia. An unusual complication in the successful treatment of massive gastrointestinal bleeding.
Scharf J, Nahir AM, Tatarski J, Barzilai A, Barzilai D
Am J Gastroenterol 1971 May;55(5):443-6. PMID: 5314681

Recent clinical studies

Etiology

Cytohistological and immunohistochemical characteristics of spindle-shaped mesenchymal neoplasms occurring in the gastrointestinal tract.
Ieni A, Barresi V, Reggiani Bonetti L, Branca G, Caruso RA, Tuccari G
Scand J Gastroenterol 2017 Mar;52(3):291-299. Epub 2016 Nov 6 doi: 10.1080/00365521.2016.1251607. PMID: 27817254
Laparoscopic Hysterectomy for Uterine Fibroids: Is it Safe?
Hinchcliff EM, Cohen SL
Clin Obstet Gynecol 2016 Mar;59(1):66-72. doi: 10.1097/GRF.0000000000000165. PMID: 26670837
Gastric schwannoma.
Lin CS, Hsu HS, Tsai CH, Li WY, Huang MH
J Chin Med Assoc 2004 Nov;67(11):583-6. PMID: 15720074
Gastrointestinal stromal tumors.
Blanke CD, Eisenberg BL, Heinrich MC
Curr Treat Options Oncol 2001 Dec;2(6):485-91. doi: 10.1007/s11864-001-0070-0. PMID: 12057094
Small intestinal neoplasms.
Gill SS, Heuman DM, Mihas AA
J Clin Gastroenterol 2001 Oct;33(4):267-82. doi: 10.1097/00004836-200110000-00004. PMID: 11588539

Diagnosis

Giant leiomyosarcoma of the transverse colon.
Nguyen C, Athigaman M, Qureshi A
BMJ Case Rep 2021 Dec 2;14(12) doi: 10.1136/bcr-2021-246646. PMID: 34857593Free PMC Article
Cytohistological and immunohistochemical characteristics of spindle-shaped mesenchymal neoplasms occurring in the gastrointestinal tract.
Ieni A, Barresi V, Reggiani Bonetti L, Branca G, Caruso RA, Tuccari G
Scand J Gastroenterol 2017 Mar;52(3):291-299. Epub 2016 Nov 6 doi: 10.1080/00365521.2016.1251607. PMID: 27817254
Testing Limits.
Massarotti EM, Sax PE, Compton L, Levy BD, Loscalzo J
N Engl J Med 2016 Oct 6;375(14):1383-1388. doi: 10.1056/NEJMcps1414259. PMID: 27705260
Sarcomas of abdominal organs: computed tomography and magnetic resonance imaging findings.
Qiu LL, Yu RS, Chen Y, Zhang Q
Semin Ultrasound CT MR 2011 Oct;32(5):405-21. doi: 10.1053/j.sult.2011.04.003. PMID: 21963162
Small bowel hemorrhage.
Netterville RE, Hardy JD, Martin RS Jr
Ann Surg 1968 Jun;167(6):949-57. doi: 10.1097/00000658-196806000-00016. PMID: 5301245Free PMC Article

Therapy

Testing Limits.
Massarotti EM, Sax PE, Compton L, Levy BD, Loscalzo J
N Engl J Med 2016 Oct 6;375(14):1383-1388. doi: 10.1056/NEJMcps1414259. PMID: 27705260
Laparoscopic Hysterectomy for Uterine Fibroids: Is it Safe?
Hinchcliff EM, Cohen SL
Clin Obstet Gynecol 2016 Mar;59(1):66-72. doi: 10.1097/GRF.0000000000000165. PMID: 26670837
Inferior Vena Cava Resection and Hemihepatectomy for Leiomyosarcoma, Utilizing Cardiopulmonary Bypass, in Situ Hepatic Perfusion, and Distal Hypothermic Circulatory Arrest.
Miles LF, Hu R, Jones RM, Carson S, McCall PR
J Cardiothorac Vasc Anesth 2016 Jan;30(1):169-75. Epub 2015 Jan 14 doi: 10.1053/j.jvca.2015.01.030. PMID: 26002188
Gastrointestinal stromal tumors.
Blanke CD, Eisenberg BL, Heinrich MC
Curr Treat Options Oncol 2001 Dec;2(6):485-91. doi: 10.1007/s11864-001-0070-0. PMID: 12057094
Splanchnic transplantation.
Foster PF, Sankary HN, McChesney L, Xiao F, Kociss K, Koukoulis G, Chong AS, Cohn S, Williams JW
Transplant Proc 1994 Jun;26(3):1411-2. PMID: 8029960

Prognosis

Small intestine leiomyosarcoma mimicking gastrointestinal stromal tumour.
Fawaz M, Kataria K, Singh A, Samadder S
BMJ Case Rep 2021 Sep 13;14(9) doi: 10.1136/bcr-2021-244381. PMID: 34518183Free PMC Article
Gastrointestinal stromal tumors.
Blanke CD, Eisenberg BL, Heinrich MC
Curr Treat Options Oncol 2001 Dec;2(6):485-91. doi: 10.1007/s11864-001-0070-0. PMID: 12057094
Small intestinal neoplasms.
Gill SS, Heuman DM, Mihas AA
J Clin Gastroenterol 2001 Oct;33(4):267-82. doi: 10.1097/00004836-200110000-00004. PMID: 11588539
Duodenal leiomyosarcoma.
Petralia GA, Hansen PD, Bowyer RC, Williamson RC
Dig Surg 1999;16(1):22-5. doi: 10.1159/000018689. PMID: 9949263
Small bowel tumors: an overview.
O'Riordan BG, Vilor M, Herrera L
Dig Dis 1996 Jul-Aug;14(4):245-57. doi: 10.1159/000171556. PMID: 8843980

Clinical prediction guides

The First Case of Metastatic Pancreatic Leiomyosarcoma Derived from the Urinary Bladder Diagnosed Using an Endoscopic Ultrasound-guided Fine-needle Biopsy.
Ishizaki A, Okuwaki K, Kida M, Imaizumi H, Iwai T, Yamauchi H, Kaneko T, Hasegawa R, Masutani H, Tadehara M, Adachi K, Watanabe M, Kurosu T, Tamaki A, Koizumi W
Intern Med 2021 May 1;60(9):1377-1381. Epub 2020 Nov 30 doi: 10.2169/internalmedicine.6143-20. PMID: 33250467Free PMC Article
Gastrointestinal stromal tumors of the stomach.
Matthews BD, Joels CS, Kercher KW, Heniford BT
Minerva Chir 2004 Jun;59(3):219-31. PMID: 15252387
Case of optic nerve involvement in metastasis of a gastrointestinal stromal tumor.
Akiyama K, Numaga J, Kagaya F, Takazawa Y, Suzuki S, Koseki N, Kato S, Kaburaki T, Kawashima H
Jpn J Ophthalmol 2004 Mar-Apr;48(2):166-8. doi: 10.1007/s10384-003-0028-9. PMID: 15060797
Total gastrectomy and oesophagojejunostomy--a prospective randomized trial of hand-sutured versus mechanically stapled anastomoses.
Seufert RM, Schmidt-Matthiesen A, Beyer A
Br J Surg 1990 Jan;77(1):50-2. doi: 10.1002/bjs.1800770118. PMID: 2405935
Myosarcomas of the small and large intestine: a clinicopathologic study.
Shiu MH, Farr GH, Egeli RA, Quan SH, Hajdu SI
J Surg Oncol 1983 Sep;24(1):67-72. doi: 10.1002/jso.2930240116. PMID: 6887940

Recent systematic reviews

Leiomyosarcoma of the rectum: A systematic review of recent literature.
Annicchiarico A, Montali F, Baldinu M, Casali L, Virgilio E, Costi R
J Surg Oncol 2024 Feb;129(2):365-380. Epub 2023 Oct 10 doi: 10.1002/jso.27481. PMID: 37814590
A pooled analysis of risk factors of surgically treated leiomyosarcoma of the colon in adults.
Wang Y, Wang H, Yuan ZL, Zhao JF, Dong DB, Gao Q
World J Surg Oncol 2020 Mar 28;18(1):61. doi: 10.1186/s12957-020-01838-3. PMID: 32222151Free PMC Article

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