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Metastatic Rectal Squamous Cell Carcinoma

MedGen UID:
1736273
•Concept ID:
C5418788
•
Neoplastic Process

Definition

Rectal squamous cell carcinoma that has spread from the original site of growth to other anatomic sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Rectal Squamous Cell Carcinoma

Professional guidelines

PubMed

Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
The treatment of squamous anal carcinoma: guidelines of the Italian Society of Colo-Rectal Surgery.
Giani I, Mistrangelo M, Fucini C; Italian Society of Colo-Rectal Surgery
Tech Coloproctol 2013 Apr;17(2):171-9. Epub 2012 Nov 10 doi: 10.1007/s10151-012-0912-8. PMID: 23143219
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695

Recent clinical studies

Etiology

Bidirectional Mendelian randomization analysis of the genetic association between primary lung cancer and colorectal cancer.
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Demographics, pattern of practice and clinical outcomes in rectal squamous cell carcinoma.
Id Said B, Buchan D, Liu Z, Kim J, Hosni A, Brierley JD, Chadi S, Grant RC, Kalimuthu S, Liu ZA, Lukovic J
Colorectal Dis 2023 Apr;25(4):608-615. Epub 2022 Nov 28 doi: 10.1111/codi.16417. PMID: 36394982
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Outcome following local excision of T1 anal cancers-a systematic review.
Pedersen TB, Kildsig J, Serup-Hansen E, Gocht-Jensen P, Klein MF
Int J Colorectal Dis 2020 Sep;35(9):1663-1671. Epub 2020 Jul 15 doi: 10.1007/s00384-020-03687-8. PMID: 32671458
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076

Diagnosis

Anal and Perianal Preneoplastic Lesions.
Loughrey MB, Shepherd NA
Gastroenterol Clin North Am 2024 Mar;53(1):201-220. Epub 2023 Oct 16 doi: 10.1016/j.gtc.2023.09.007. PMID: 38280748
Bidirectional Mendelian randomization analysis of the genetic association between primary lung cancer and colorectal cancer.
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
An Updated Review on Imaging and Staging of Anal Cancer-Not Just Rectal Cancer.
Congedo A, Mallardi D, Danti G, De Muzio F, Granata V, Miele V
Tomography 2023 Sep 4;9(5):1694-1710. doi: 10.3390/tomography9050135. PMID: 37736988Free PMC Article
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Multimodality Imaging Review of Anorectal and Perirectal Diseases With Histological, Endoscopic, and Operative Correlation, Part I: Anatomy and Neoplasms.
Sangster GP, Ballard DH, Nazar M, Tsai R, Donato M, D'Agostino HB
Curr Probl Diagn Radiol 2019 Sep-Oct;48(5):494-508. Epub 2018 Jul 29 doi: 10.1067/j.cpradiol.2018.07.015. PMID: 30172447Free PMC Article

Therapy

Bidirectional Mendelian randomization analysis of the genetic association between primary lung cancer and colorectal cancer.
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Anal Cancer and Anal Cancer Screening.
Cohen CM, Clarke MA
Clin Obstet Gynecol 2023 Sep 1;66(3):516-533. Epub 2023 Jul 13 doi: 10.1097/GRF.0000000000000789. PMID: 37439541Free PMC Article
Practice changing data and emerging concepts from recent radiation therapy randomised clinical trials.
Espenel S, Chargari C, Blanchard P, Bockel S, Morel D, Rivera S, Levy A, Deutsch E
Eur J Cancer 2022 Aug;171:242-258. Epub 2022 Jun 29 doi: 10.1016/j.ejca.2022.04.038. PMID: 35779346
Squamous rectal carcinoma: a rare malignancy, literature review and management recommendations.
Astaras C, Bornand A, Koessler T
ESMO Open 2021 Aug;6(4):100180. Epub 2021 Jun 7 doi: 10.1016/j.esmoop.2021.100180. PMID: 34111760Free PMC Article
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076

Prognosis

Bidirectional Mendelian randomization analysis of the genetic association between primary lung cancer and colorectal cancer.
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Secondary Squamous Cell Carcinoma of Prostate: A Case Report.
Chen Q, Ye J, Li X, Chen R, Zeng S
Arch Esp Urol 2023 Jun;76(4):309-312. doi: 10.56434/j.arch.esp.urol.20237604.35. PMID: 37455530
Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial.
Gupta S, Maheshwari A, Parab P, Mahantshetty U, Hawaldar R, Sastri Chopra S, Kerkar R, Engineer R, Tongaonkar H, Ghosh J, Gulia S, Kumar N, Shylasree TS, Gawade R, Kembhavi Y, Gaikar M, Menon S, Thakur M, Shrivastava S, Badwe R
J Clin Oncol 2018 Jun 1;36(16):1548-1555. Epub 2018 Feb 12 doi: 10.1200/JCO.2017.75.9985. PMID: 29432076
Squamous cell carcinoma associated anal fistulas in Crohn's disease unique case report with literature review.
Benjelloun el B, Abkari M, Ousadden A, Ait Taleb K
J Crohns Colitis 2013 Jul;7(6):e232-5. Epub 2012 Oct 12 doi: 10.1016/j.crohns.2012.09.015. PMID: 23069004
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695

Clinical prediction guides

Bidirectional Mendelian randomization analysis of the genetic association between primary lung cancer and colorectal cancer.
Xiao Z, Wang Z, Zhang T, Liu Y, Si M
J Transl Med 2023 Oct 15;21(1):722. doi: 10.1186/s12967-023-04612-7. PMID: 37840123Free PMC Article
Demographics, pattern of practice and clinical outcomes in rectal squamous cell carcinoma.
Id Said B, Buchan D, Liu Z, Kim J, Hosni A, Brierley JD, Chadi S, Grant RC, Kalimuthu S, Liu ZA, Lukovic J
Colorectal Dis 2023 Apr;25(4):608-615. Epub 2022 Nov 28 doi: 10.1111/codi.16417. PMID: 36394982
Coexpress of GATA-3 and ER in Anorectal and Head and Neck Squamous Cell Carcinoma Mimicking Metastatic Breast Cancer.
Wang Y, Lu S, Amin A, Wang L
Appl Immunohistochem Mol Morphol 2021 Jul 1;29(6):409-413. doi: 10.1097/PAI.0000000000000887. PMID: 33264107
Adenosquamous Cell Carcinoma of the Rectum in a Girl: First Case Reported and Review of the Literature.
García NÁ, Hernando Cubero J, Alonso Orduña V, Torrecilla Idoipe N, Calvo Escribano C, Fernandez Atuán R
J Pediatr Hematol Oncol 2015 Aug;37(6):e364-7. doi: 10.1097/MPH.0000000000000361. PMID: 26181422
Chemoradiotherapy in the management of primary squamous-cell carcinoma of the rectum.
Wang ML, Heriot A, Leong T, Ngan SY
Colorectal Dis 2011 Mar;13(3):296-301. doi: 10.1111/j.1463-1318.2009.02154.x. PMID: 20002695

Recent systematic reviews

Outcome following local excision of T1 anal cancers-a systematic review.
Pedersen TB, Kildsig J, Serup-Hansen E, Gocht-Jensen P, Klein MF
Int J Colorectal Dis 2020 Sep;35(9):1663-1671. Epub 2020 Jul 15 doi: 10.1007/s00384-020-03687-8. PMID: 32671458

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