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Renal interstitial hemorrhage

MedGen UID:
1715002
Concept ID:
C5397638
Pathologic Function
Synonym: Renal interstitial haemorrhage
 
HPO: HP:0032617

Definition

A focal collection of 20 or more red blood cells within the interstitium, that is irregular in shape (i.e., collections do not conform to the shape of tubules or capillary networks), without surrounding endothelium or tubular epithelium, and is in an area of intact core. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Bridoux F, Leung N, Belmouaz M, Royal V, Ronco P, Nasr SH, Fermand JP; International Kidney and Monoclonal Gammopathy Research Group
Kidney Int 2021 Mar;99(3):570-580. Epub 2021 Jan 10 doi: 10.1016/j.kint.2020.11.010. PMID: 33440212
Cavanaugh C, Perazella MA
Am J Kidney Dis 2019 Feb;73(2):258-272. Epub 2018 Sep 21 doi: 10.1053/j.ajkd.2018.07.012. PMID: 30249419
Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS
Blood 2017 Mar 23;129(12):1646-1657. Epub 2017 Jan 13 doi: 10.1182/blood-2016-10-746933. PMID: 28087540Free PMC Article

Recent clinical studies

Etiology

Gong K, Xia M, Wang Y, Wang N, Liu Y, Zhang VW, Cheng H, Chen Y
Sci Rep 2021 Feb 11;11(1):3615. doi: 10.1038/s41598-020-79331-w. PMID: 33574344Free PMC Article
Haas M, Loupy A, Lefaucheur C, Roufosse C, Glotz D, Seron D, Nankivell BJ, Halloran PF, Colvin RB, Akalin E, Alachkar N, Bagnasco S, Bouatou Y, Becker JU, Cornell LD, Duong van Huyen JP, Gibson IW, Kraus ES, Mannon RB, Naesens M, Nickeleit V, Nickerson P, Segev DL, Singh HK, Stegall M, Randhawa P, Racusen L, Solez K, Mengel M
Am J Transplant 2018 Feb;18(2):293-307. Epub 2018 Jan 21 doi: 10.1111/ajt.14625. PMID: 29243394Free PMC Article
Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS
Blood 2017 Mar 23;129(12):1646-1657. Epub 2017 Jan 13 doi: 10.1182/blood-2016-10-746933. PMID: 28087540Free PMC Article
Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B
Autoimmun Rev 2015 Jul;14(7):579-85. Epub 2015 Feb 14 doi: 10.1016/j.autrev.2015.02.003. PMID: 25688001
Mosquera Reboredo JM, Vázquez Martul E
Nefrologia 2011;31(4):382-91. doi: 10.3265/Nefrologia.pre2011.Apr.10740. PMID: 21738242

Diagnosis

AlYousef A, AlSahow A, AlHelal B, Alqallaf A, Abdallah E, Abdellatif M, Nawar H, Elmahalawy R
BMC Nephrol 2020 May 18;21(1):186. doi: 10.1186/s12882-020-01836-3. PMID: 32423387Free PMC Article
Lusica M, Rondon-Berrios H, Feldman L
J Hosp Med 2017 May;12(5):343-345. doi: 10.12788/jhm.2737. PMID: 28459905
Kawano M, Yamada K
Semin Liver Dis 2016 Aug;36(3):283-90. Epub 2016 Jul 28 doi: 10.1055/s-0036-1584316. PMID: 27466797
Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B
Autoimmun Rev 2015 Jul;14(7):579-85. Epub 2015 Feb 14 doi: 10.1016/j.autrev.2015.02.003. PMID: 25688001
El-Zoghby Z, Lager D, Gregoire J, Lewin M, Sethi S
Kidney Int 2007 Nov;72(10):1282-8. Epub 2007 Jul 4 doi: 10.1038/sj.ki.5002411. PMID: 17609690

Therapy

Glastras SJ, Chen H, Teh R, McGrath RT, Chen J, Pollock CA, Wong MG, Saad S
PLoS One 2016;11(8):e0162131. Epub 2016 Aug 31 doi: 10.1371/journal.pone.0162131. PMID: 27579698Free PMC Article
Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B
Autoimmun Rev 2015 Jul;14(7):579-85. Epub 2015 Feb 14 doi: 10.1016/j.autrev.2015.02.003. PMID: 25688001
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304
Sitprija V
Nephrology (Carlton) 2006 Oct;11(5):442-8. doi: 10.1111/j.1440-1797.2006.00599.x. PMID: 17014559
Pope JE
Rheum Dis Clin North Am 1996 Nov;22(4):893-907. doi: 10.1016/s0889-857x(05)70307-0. PMID: 8923602

Prognosis

Seethapathy H, Zhao S, Chute DF, Zubiri L, Oppong Y, Strohbehn I, Cortazar FB, Leaf DE, Mooradian MJ, Villani AC, Sullivan RJ, Reynolds K, Sise ME
Clin J Am Soc Nephrol 2019 Dec 6;14(12):1692-1700. Epub 2019 Oct 31 doi: 10.2215/CJN.00990119. PMID: 31672794Free PMC Article
Wen YK
Saudi J Kidney Dis Transpl 2018 Nov-Dec;29(6):1502-1505. doi: 10.4103/1319-2442.248281. PMID: 30588987
Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B
Autoimmun Rev 2015 Jul;14(7):579-85. Epub 2015 Feb 14 doi: 10.1016/j.autrev.2015.02.003. PMID: 25688001
Mosquera Reboredo JM, Vázquez Martul E
Nefrologia 2011;31(4):382-91. doi: 10.3265/Nefrologia.pre2011.Apr.10740. PMID: 21738242
Hocken AG, Bradshaw G
Br J Ind Med 1970 Jan;27(1):56-60. doi: 10.1136/oem.27.1.56. PMID: 5418920Free PMC Article

Clinical prediction guides

AlYousef A, AlSahow A, AlHelal B, Alqallaf A, Abdallah E, Abdellatif M, Nawar H, Elmahalawy R
BMC Nephrol 2020 May 18;21(1):186. doi: 10.1186/s12882-020-01836-3. PMID: 32423387Free PMC Article
Miller WL
Circ Heart Fail 2016 Aug;9(8):e002922. doi: 10.1161/CIRCHEARTFAILURE.115.002922. PMID: 27436837
Coppo R, Troyanov S, Bellur S, Cattran D, Cook HT, Feehally J, Roberts IS, Morando L, Camilla R, Tesar V, Lunberg S, Gesualdo L, Emma F, Rollino C, Amore A, Praga M, Feriozzi S, Segoloni G, Pani A, Cancarini G, Durlik M, Moggia E, Mazzucco G, Giannakakis C, Honsova E, Sundelin BB, Di Palma AM, Ferrario F, Gutierrez E, Asunis AM, Barratt J, Tardanico R, Perkowska-Ptasinska A; VALIGA study of the ERA-EDTA Immunonephrology Working Group
Kidney Int 2014 Oct;86(4):828-36. Epub 2014 Apr 2 doi: 10.1038/ki.2014.63. PMID: 24694989Free PMC Article
Saeki T, Kawano M
Kidney Int 2014 Feb;85(2):251-7. Epub 2013 Oct 9 doi: 10.1038/ki.2013.393. PMID: 24107849
Cornell LD
Semin Diagn Pathol 2012 Nov;29(4):245-50. doi: 10.1053/j.semdp.2012.07.004. PMID: 23068304

Recent systematic reviews

Genovese F, Bager C, Frederiksen P, Vazquez D, Sand JMB, Jenkins RG, Maher TM, Stewart ID, Molyneaux PL, Fahy WA, Wain LV, Vestbo J, Nanthakumar C, Shaker SB, Hoyer N, Leeming DJ, George J, Trebicka J, Rasmussen DGK, Hansen MK, Cockwell P, Kremer D, Bakker SJ, Selby NM, Reese-Petersen AL, González A, Núñez J, Rossing P, Nissen NI, Boisen MK, Chen IM, Zhao L, Karsdal MA, Schuppan D
Matrix Biol 2024 Sep;132:1-9. Epub 2024 Jun 11 doi: 10.1016/j.matbio.2024.06.003. PMID: 38871093
Gomes AM, Lopes D, Almeida C, Santos S, Malheiro J, Lousa I, Caldas Afonso A, Beirão I
Int J Mol Sci 2022 Jun 30;23(13) doi: 10.3390/ijms23137276. PMID: 35806283Free PMC Article
Corthier A, Jachiet M, Bertin D, Servais A, Barbet C, Bigot A, Doutre MS, Bessis D, Bouffandeau A, Moranne O, Jarrot PA, Bardin N, Terrier B, Burtey S, Puéchal X, Daniel L, Jourde-Chiche N
BMC Nephrol 2022 Feb 16;23(1):67. doi: 10.1186/s12882-022-02689-8. PMID: 35172758Free PMC Article
Luo X, Tan J, Wan D, Chen J, Hu Y
Int Urol Nephrol 2022 Jan;54(1):99-109. Epub 2021 Apr 27 doi: 10.1007/s11255-021-02861-3. PMID: 33905044
Martínez-Valenzuela L, Draibe J, Fulladosa X, Gomà M, Gómez F, Antón P, Cruzado JM, Torras J
Int J Mol Sci 2021 Feb 26;22(5) doi: 10.3390/ijms22052326. PMID: 33652638Free PMC Article

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