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Early Stage Pancreatic Ductal Adenocarcinoma

MedGen UID:
1698717
Concept ID:
C5204114
Neoplastic Process

Definition

Pancreatic ductal adenocarcinoma that has not spread beyond the pancreas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEarly Stage Pancreatic Ductal Adenocarcinoma

Professional guidelines

PubMed

Manne A, Esnakula A, Sheel A, Sara A, Manne U, Paluri RK, He K, Yang W, Sohal D, Kasi A, Noonan AM, Mittra A, Hays J, Roychowdhury S, Malalur P, Rahman S, Jin N, Cloyd JM, Tsai S, Ejaz A, Pitter K, Miller E, Thanikachalam K, Dillhoff M, Yu L
Int J Mol Sci 2024 Aug 20;25(16) doi: 10.3390/ijms25169041. PMID: 39201728Free PMC Article
Tanaka H, Tamura K, Abe T, Yoshida T, Macgregor-Das A, Dbouk M, Blackford AL, Borges M, Lennon AM, He J, Burkhart R, Canto MI, Goggins M
Clin Gastroenterol Hepatol 2022 Oct;20(10):2267-2275.e2. Epub 2021 Oct 12 doi: 10.1016/j.cgh.2021.10.008. PMID: 34648951Free PMC Article

Recent clinical studies

Etiology

Gao H, Liu T, Wang G, Gao Y, Yin L, Peng Y, Lyu N, Zhang K, Gao W, Wu J, Jiang K, Wei J, Miao Y
Langenbecks Arch Surg 2019 Mar;404(2):175-182. Epub 2019 Mar 2 doi: 10.1007/s00423-019-01766-1. PMID: 30826926
Lee AJ, Simoneau E, Chiang YJ, Lee JE, Kim MP, Aloia TA, Vauthey JN, Katz MH, Tzeng CD
HPB (Oxford) 2019 Sep;21(9):1203-1210. Epub 2019 Feb 22 doi: 10.1016/j.hpb.2019.01.011. PMID: 30799277
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051
Kimura H, Ohtsuka T, Matsunaga T, Watanabe Y, Tamura K, Ideno N, Aso T, Miyazaki T, Osoegawa T, Aishima S, Miyasaka Y, Ueda J, Ushijima Y, Igarashi H, Ito T, Takahata S, Oda Y, Mizumoto K, Tanaka M
Pancreas 2015 Oct;44(7):1148-54. doi: 10.1097/MPA.0000000000000393. PMID: 26284536
Chen DT, Davis-Yadley AH, Huang PY, Husain K, Centeno BA, Permuth-Wey J, Pimiento JM, Malafa M
PLoS One 2015;10(8):e0133562. Epub 2015 Aug 6 doi: 10.1371/journal.pone.0133562. PMID: 26247463Free PMC Article

Diagnosis

Firpo MA, Boucher KM, Bleicher J, Khanderao GD, Rosati A, Poruk KE, Kamal S, Marzullo L, De Marco M, Falco A, Genovese A, Adler JM, De Laurenzi V, Adler DG, Affolter KE, Garrido-Laguna I, Scaife CL, Turco MC, Mulvihill SJ
JCO Clin Cancer Inform 2023 Mar;7:e2200160. doi: 10.1200/CCI.22.00160. PMID: 36913644Free PMC Article
Nevler A, Khalilieh S, Lavu H, Bowne W, Yeo CJ
J Am Coll Surg 2023 Apr 1;236(4):913-922. Epub 2023 Jan 10 doi: 10.1097/XCS.0000000000000552. PMID: 36728372
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051
Kimura H, Ohtsuka T, Matsunaga T, Watanabe Y, Tamura K, Ideno N, Aso T, Miyazaki T, Osoegawa T, Aishima S, Miyasaka Y, Ueda J, Ushijima Y, Igarashi H, Ito T, Takahata S, Oda Y, Mizumoto K, Tanaka M
Pancreas 2015 Oct;44(7):1148-54. doi: 10.1097/MPA.0000000000000393. PMID: 26284536
Chen DT, Davis-Yadley AH, Huang PY, Husain K, Centeno BA, Permuth-Wey J, Pimiento JM, Malafa M
PLoS One 2015;10(8):e0133562. Epub 2015 Aug 6 doi: 10.1371/journal.pone.0133562. PMID: 26247463Free PMC Article

Therapy

Manne A, Esnakula A, Sheel A, Sara A, Manne U, Paluri RK, He K, Yang W, Sohal D, Kasi A, Noonan AM, Mittra A, Hays J, Roychowdhury S, Malalur P, Rahman S, Jin N, Cloyd JM, Tsai S, Ejaz A, Pitter K, Miller E, Thanikachalam K, Dillhoff M, Yu L
Int J Mol Sci 2024 Aug 20;25(16) doi: 10.3390/ijms25169041. PMID: 39201728Free PMC Article
Ponzini FM, Schultz CW, Leiby BE, Cannaday S, Yeo T, Posey J, Bowne WB, Yeo C, Brody JR, Lavu H, Nevler A
BMJ Open 2023 Oct 17;13(10):e073839. doi: 10.1136/bmjopen-2023-073839. PMID: 37848297Free PMC Article
Liu XG, Xu H, Chen M, Tan XY, Chen XF, Yang YG, Lin MZ, Liu GH, Liang XL, Qian YB, Yuan GJ, Chen MQ, Li WT, Miao HL, Li MY, Liao XW, Dai W, Chen NP
Cancer Med 2020 Mar;9(6):2062-2076. Epub 2020 Jan 28 doi: 10.1002/cam4.2818. PMID: 31991068Free PMC Article
Gao H, Liu T, Wang G, Gao Y, Yin L, Peng Y, Lyu N, Zhang K, Gao W, Wu J, Jiang K, Wei J, Miao Y
Langenbecks Arch Surg 2019 Mar;404(2):175-182. Epub 2019 Mar 2 doi: 10.1007/s00423-019-01766-1. PMID: 30826926
Bergquist JR, Puig CA, Shubert CR, Groeschl RT, Habermann EB, Kendrick ML, Nagorney DM, Smoot RL, Farnell MB, Truty MJ
J Am Coll Surg 2016 Jul;223(1):52-65. Epub 2016 Feb 23 doi: 10.1016/j.jamcollsurg.2016.02.009. PMID: 27049786

Prognosis

Nevler A, Khalilieh S, Lavu H, Bowne W, Yeo CJ
J Am Coll Surg 2023 Apr 1;236(4):913-922. Epub 2023 Jan 10 doi: 10.1097/XCS.0000000000000552. PMID: 36728372
Gao H, Liu T, Wang G, Gao Y, Yin L, Peng Y, Lyu N, Zhang K, Gao W, Wu J, Jiang K, Wei J, Miao Y
Langenbecks Arch Surg 2019 Mar;404(2):175-182. Epub 2019 Mar 2 doi: 10.1007/s00423-019-01766-1. PMID: 30826926
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051
Kimura H, Ohtsuka T, Matsunaga T, Watanabe Y, Tamura K, Ideno N, Aso T, Miyazaki T, Osoegawa T, Aishima S, Miyasaka Y, Ueda J, Ushijima Y, Igarashi H, Ito T, Takahata S, Oda Y, Mizumoto K, Tanaka M
Pancreas 2015 Oct;44(7):1148-54. doi: 10.1097/MPA.0000000000000393. PMID: 26284536
Chen DT, Davis-Yadley AH, Huang PY, Husain K, Centeno BA, Permuth-Wey J, Pimiento JM, Malafa M
PLoS One 2015;10(8):e0133562. Epub 2015 Aug 6 doi: 10.1371/journal.pone.0133562. PMID: 26247463Free PMC Article

Clinical prediction guides

Firpo MA, Boucher KM, Bleicher J, Khanderao GD, Rosati A, Poruk KE, Kamal S, Marzullo L, De Marco M, Falco A, Genovese A, Adler JM, De Laurenzi V, Adler DG, Affolter KE, Garrido-Laguna I, Scaife CL, Turco MC, Mulvihill SJ
JCO Clin Cancer Inform 2023 Mar;7:e2200160. doi: 10.1200/CCI.22.00160. PMID: 36913644Free PMC Article
Nevler A, Khalilieh S, Lavu H, Bowne W, Yeo CJ
J Am Coll Surg 2023 Apr 1;236(4):913-922. Epub 2023 Jan 10 doi: 10.1097/XCS.0000000000000552. PMID: 36728372
Shi J, Li X, Wu Y
Zhejiang Da Xue Xue Bao Yi Xue Ban 2021 Jun 25;50(3):375-382. doi: 10.3724/zdxbyxb-2021-0194. PMID: 34402250Free PMC Article
Kimura H, Ohtsuka T, Matsunaga T, Watanabe Y, Tamura K, Ideno N, Aso T, Miyazaki T, Osoegawa T, Aishima S, Miyasaka Y, Ueda J, Ushijima Y, Igarashi H, Ito T, Takahata S, Oda Y, Mizumoto K, Tanaka M
Pancreas 2015 Oct;44(7):1148-54. doi: 10.1097/MPA.0000000000000393. PMID: 26284536
Chen DT, Davis-Yadley AH, Huang PY, Husain K, Centeno BA, Permuth-Wey J, Pimiento JM, Malafa M
PLoS One 2015;10(8):e0133562. Epub 2015 Aug 6 doi: 10.1371/journal.pone.0133562. PMID: 26247463Free PMC Article

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