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Tracheal papilloma

MedGen UID:
1687702
•Concept ID:
C1868836
•
Neoplastic Process
HPO: HP:0033003

Definition

A wart-like lesion (papilloma, i.e., benign epithelial tumors that are caused by infection with the human papilloma virus) located on the trachea. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTracheal papilloma

Professional guidelines

PubMed

Update on Pathologic Conditions, Imaging Findings, Prevention, and Management of Human Papillomavirus-related Neoplasms.
Katabathina VS, Ghannam S, Chen M, Desalme B, Gabos R, Emejulu I, Sandhu PK, Valente P, Dasyam AK, Prasad SR
Radiographics 2024 Aug;44(8):e230179. doi: 10.1148/rg.230179. PMID: 39024173
Current diagnostic and management trends for recurrent respiratory papillomatosis.
Silverman DA, Pitman MJ
Curr Opin Otolaryngol Head Neck Surg 2004 Dec;12(6):532-7. doi: 10.1097/01.moo.0000144392.33250.15. PMID: 15548913
Adjuvant drug strategies in the treatment of recurrent respiratory papillomatosis.
Avidano MA, Singleton GT
Otolaryngol Head Neck Surg 1995 Feb;112(2):197-202. doi: 10.1016/S0194-59989570236-9. PMID: 7530830

Recent clinical studies

Etiology

Parenteral Bevacizumab for the Treatment of Severe Respiratory Papillomatosis in an Adult Population.
Tkaczuk A, Trivedi S, Mody MD, Steuer CE, Shin DM, Klein AM, Saba NF
Laryngoscope 2021 Mar;131(3):E921-E928. Epub 2020 Oct 27 doi: 10.1002/lary.29133. PMID: 33107615

Diagnosis

Solitary Tracheal Papilloma.
Ko Y, Kim C, Park YB
Am J Respir Crit Care Med 2020 Aug 15;202(4):e88-e89. doi: 10.1164/rccm.201911-2147IM. PMID: 32352835
Systemic bevacizumab for recurrent respiratory papillomatosis: A national survey.
Best SR, Mohr M, Zur KB
Laryngoscope 2017 Oct;127(10):2225-2229. Epub 2017 Jun 28 doi: 10.1002/lary.26662. PMID: 28657692Free PMC Article
Primary tracheal papilloma disguised as asthma: A case report.
Chen YB, Jiang JH, Guo LC, Huang JA
J Asthma 2016 Dec;53(10):1090-3. Epub 2016 May 4 doi: 10.3109/02770903.2016.1171872. PMID: 27144426
A Case of the Intrapulmonary Spread of Recurrent Respiratory Papillomatosis With Malignant Transformation.
Xiao Y, Wang J, Han D, Ma L
Am J Med Sci 2015 Jul;350(1):55-7. doi: 10.1097/MAJ.0000000000000370. PMID: 25423295Free PMC Article
Human papillomavirus and squamous cell carcinoma in a solitary tracheal papilloma.
Lam CW, Talbot AR, Yeh KT, Lin SC, Hsieh CE, Fang HY
Ann Thorac Surg 2004 Jun;77(6):2201-2. doi: 10.1016/S0003-4975(03)01285-2. PMID: 15172304

Therapy

Parenteral Bevacizumab for the Treatment of Severe Respiratory Papillomatosis in an Adult Population.
Tkaczuk A, Trivedi S, Mody MD, Steuer CE, Shin DM, Klein AM, Saba NF
Laryngoscope 2021 Mar;131(3):E921-E928. Epub 2020 Oct 27 doi: 10.1002/lary.29133. PMID: 33107615
Systemic bevacizumab for recurrent respiratory papillomatosis: A national survey.
Best SR, Mohr M, Zur KB
Laryngoscope 2017 Oct;127(10):2225-2229. Epub 2017 Jun 28 doi: 10.1002/lary.26662. PMID: 28657692Free PMC Article

Prognosis

Tracheo-bronchial recurrent respiratory papillomatosis: role of powered instruments in overcoming surgical challenges.
Sikka K, Gupta M, Verma H, Kumar R, Thakar A
Acta Otorhinolaryngol Ital 2021 Apr;41(2):146-150. doi: 10.14639/0392-100X-N0822. PMID: 34028459Free PMC Article
A Case of the Intrapulmonary Spread of Recurrent Respiratory Papillomatosis With Malignant Transformation.
Xiao Y, Wang J, Han D, Ma L
Am J Med Sci 2015 Jul;350(1):55-7. doi: 10.1097/MAJ.0000000000000370. PMID: 25423295Free PMC Article
Tracheal papilloma with exceptionally longer interval of recurrence.
Komatsu T, Takahashi Y
Asian J Surg 2007 Jan;30(1):88-90. doi: 10.1016/S1015-9584(09)60137-8. PMID: 17337381

Clinical prediction guides

Parenteral Bevacizumab for the Treatment of Severe Respiratory Papillomatosis in an Adult Population.
Tkaczuk A, Trivedi S, Mody MD, Steuer CE, Shin DM, Klein AM, Saba NF
Laryngoscope 2021 Mar;131(3):E921-E928. Epub 2020 Oct 27 doi: 10.1002/lary.29133. PMID: 33107615
Xenograft model for therapeutic drug testing in recurrent respiratory papillomatosis.
Ahn J, Bishop JA, Akpeng B, Pai SI, Best SR
Ann Otol Rhinol Laryngol 2015 Feb;124(2):110-5. Epub 2014 Aug 13 doi: 10.1177/0003489414546400. PMID: 25124839Free PMC Article

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