U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Abnormal circulating pyrimidine concentration

MedGen UID:
1684685
Concept ID:
C5139038
Finding
Synonym: Abnormality of pyrimidine metabolism
 
HPO: HP:0004353

Definition

Any deviation from the normal concentration of a pyrimidine in the blood circulation. [from HPO]

Recent clinical studies

Etiology

Chen Y, Liu H, Zheng Q, Li H, You H, Feng Y, Feng W
Life Sci 2022 Oct 1;306:120826. Epub 2022 Jul 21 doi: 10.1016/j.lfs.2022.120826. PMID: 35870618
Courlet P, Alves Saldanha S, Cavassini M, Marzolini C, Choong E, Csajka C, Günthard HF, André P, Buclin T, Desfontaine V, Decosterd LA
J Mass Spectrom 2020 Jun;55(6):e4506. Epub 2020 Mar 11 doi: 10.1002/jms.4506. PMID: 32160389Free PMC Article
Goldberg DJ, Zak V, Goldstein BH, Chen S, Hamstra MS, Radojewski EA, Maunsell E, Mital S, Menon SC, Schumacher KR, Payne RM, Stylianou M, Kaltman JR, deVries TM, Yeager JL, Paridon SM; Pediatric Heart Network Investigators
Am Heart J 2017 Jun;188:42-52. Epub 2017 Mar 6 doi: 10.1016/j.ahj.2017.02.030. PMID: 28577680Free PMC Article
Pitkänen OP, Nuutila P, Raitakari OT, Rönnemaa T, Koskinen PJ, Iida H, Lehtimäki TJ, Laine HK, Takala T, Viikari JS, Knuuti J
Diabetes 1998 Feb;47(2):248-54. doi: 10.2337/diab.47.2.248. PMID: 9519721
Wiebe VJ, Sipila PE
Crit Rev Oncol Hematol 1994 Apr;16(2):75-112. doi: 10.1016/1040-8428(94)90043-4. PMID: 8068213

Diagnosis

Courlet P, Alves Saldanha S, Cavassini M, Marzolini C, Choong E, Csajka C, Günthard HF, André P, Buclin T, Desfontaine V, Decosterd LA
J Mass Spectrom 2020 Jun;55(6):e4506. Epub 2020 Mar 11 doi: 10.1002/jms.4506. PMID: 32160389Free PMC Article
Picano E, Parodi O, Lattanzi F, Sambuceti G, Andrade MJ, Marzullo P, Giorgetti A, Salvadori P, Marzilli M, Distante A
Circulation 1994 Feb;89(2):753-61. doi: 10.1161/01.cir.89.2.753. PMID: 8313564
Baker JR Jr, Lukes YG, Smallridge RC, Berger M, Burman KD
J Clin Invest 1983 Oct;72(4):1487-97. doi: 10.1172/JCI111105. PMID: 6138364Free PMC Article
Narita M, Kurihara T, Usami M
Jpn Circ J 1981 Jan;45(1):127-40. doi: 10.1253/jcj.45.127. PMID: 6779029
Kawai C, Wakabayashi A, Matsumura T, Yui Y
Am J Med 1980 Sep;69(3):383-6. doi: 10.1016/0002-9343(80)90008-x. PMID: 7416185

Therapy

Kohara S, Kamijo Y, Seki S, Hasegawa E
Am J Emerg Med 2023 Oct;72:221.e5-221.e7. Epub 2023 Aug 22 doi: 10.1016/j.ajem.2023.08.034. PMID: 37635049
Chen Y, Liu H, Zheng Q, Li H, You H, Feng Y, Feng W
Life Sci 2022 Oct 1;306:120826. Epub 2022 Jul 21 doi: 10.1016/j.lfs.2022.120826. PMID: 35870618
Courlet P, Alves Saldanha S, Cavassini M, Marzolini C, Choong E, Csajka C, Günthard HF, André P, Buclin T, Desfontaine V, Decosterd LA
J Mass Spectrom 2020 Jun;55(6):e4506. Epub 2020 Mar 11 doi: 10.1002/jms.4506. PMID: 32160389Free PMC Article
Goldberg DJ, Zak V, Goldstein BH, Chen S, Hamstra MS, Radojewski EA, Maunsell E, Mital S, Menon SC, Schumacher KR, Payne RM, Stylianou M, Kaltman JR, deVries TM, Yeager JL, Paridon SM; Pediatric Heart Network Investigators
Am Heart J 2017 Jun;188:42-52. Epub 2017 Mar 6 doi: 10.1016/j.ahj.2017.02.030. PMID: 28577680Free PMC Article
Wiebe VJ, Sipila PE
Crit Rev Oncol Hematol 1994 Apr;16(2):75-112. doi: 10.1016/1040-8428(94)90043-4. PMID: 8068213

Prognosis

Courlet P, Alves Saldanha S, Cavassini M, Marzolini C, Choong E, Csajka C, Günthard HF, André P, Buclin T, Desfontaine V, Decosterd LA
J Mass Spectrom 2020 Jun;55(6):e4506. Epub 2020 Mar 11 doi: 10.1002/jms.4506. PMID: 32160389Free PMC Article
Goldberg DJ, Zak V, Goldstein BH, Chen S, Hamstra MS, Radojewski EA, Maunsell E, Mital S, Menon SC, Schumacher KR, Payne RM, Stylianou M, Kaltman JR, deVries TM, Yeager JL, Paridon SM; Pediatric Heart Network Investigators
Am Heart J 2017 Jun;188:42-52. Epub 2017 Mar 6 doi: 10.1016/j.ahj.2017.02.030. PMID: 28577680Free PMC Article
Elliott PM, Rosano GM, Gill JS, Poole-Wilson PA, Kaski JC, McKenna WJ
Heart 1996 Feb;75(2):179-83. doi: 10.1136/hrt.75.2.179. PMID: 8673758Free PMC Article

Clinical prediction guides

Chen Y, Liu H, Zheng Q, Li H, You H, Feng Y, Feng W
Life Sci 2022 Oct 1;306:120826. Epub 2022 Jul 21 doi: 10.1016/j.lfs.2022.120826. PMID: 35870618
Caslake MJ, Stewart G, Day SP, Daly E, McTaggart F, Chapman MJ, Durrington P, Laggner P, Mackness M, Pears J, Packard CJ
Atherosclerosis 2003 Dec;171(2):245-53. doi: 10.1016/j.atherosclerosis.2003.08.025. PMID: 14644393
Pitkänen OP, Nuutila P, Raitakari OT, Porkka K, Iida H, Nuotio I, Rönnemaa T, Viikari J, Taskinen MR, Ehnholm C, Knuuti J
Circulation 1999 Apr 6;99(13):1678-84. doi: 10.1161/01.cir.99.13.1678. PMID: 10190876
Pitkänen OP, Raitakari OT, Niinikoski H, Nuutila P, Iida H, Voipio-Pulkki LM, Härkönen R, Wegelius U, Rönnemaa T, Viikari J, Knuuti J
J Am Coll Cardiol 1996 Dec;28(7):1705-11. doi: 10.1016/S0735-1097(96)00376-2. PMID: 8962555
Picano E, Parodi O, Lattanzi F, Sambuceti G, Andrade MJ, Marzullo P, Giorgetti A, Salvadori P, Marzilli M, Distante A
Circulation 1994 Feb;89(2):753-61. doi: 10.1161/01.cir.89.2.753. PMID: 8313564

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...