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Nonpolyposis colon cancer

MedGen UID:
1682427
•Concept ID:
C5194038
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNonpolyposis colon cancer

Professional guidelines

PubMed

Management of endometrial precancers.
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Psychological opportunities and hazards in predictive genetic testing for cancer risk.
Codori AM
Gastroenterol Clin North Am 1997 Mar;26(1):19-39. doi: 10.1016/s0889-8553(05)70281-8. PMID: 9119438
Contributions of molecular genetics to the clinical management of colorectal cancer.
Sterm HS
Am J Surg 1996 Jan;171(1):10-5. doi: 10.1016/s0002-9610(99)80065-8. PMID: 8554121

Recent clinical studies

Etiology

An Update on Inherited Colon Cancer and Gastrointestinal Polyposis.
Plevová P
Klin Onkol 2019 Summer;32(Supplementum2):97-108. doi: 10.14735/amko2019S97. PMID: 31409085
Novel biallelic mutations in MSH6 and PMS2 genes: gene conversion as a likely cause of PMS2 gene inactivation.
Auclair J, Leroux D, Desseigne F, Lasset C, Saurin JC, Joly MO, Pinson S, Xu XL, Montmain G, Ruano E, Navarro C, Puisieux A, Wang Q
Hum Mutat 2007 Nov;28(11):1084-90. doi: 10.1002/humu.20569. PMID: 17557300
Familial adenomatous polyposis, hereditary nonpolyposis colon cancer, and familial risk: what are the implications for the surgeon?
Thorson AG, Faria J
Surg Oncol Clin N Am 2000 Oct;9(4):683-97; discussion 699-701. PMID: 11008233
Mismatch repair proteins and microsatellites hit clinical practice.
Stahl J
Adv Anat Pathol 2000 Mar;7(2):85-93. doi: 10.1097/00125480-200007020-00003. PMID: 10721415
Hereditary ovarian carcinoma.
Gallion HH, Smith SA
Semin Surg Oncol 1994 Jul-Aug;10(4):249-54. doi: 10.1002/ssu.2980100404. PMID: 8091066

Diagnosis

An Update on Inherited Colon Cancer and Gastrointestinal Polyposis.
Plevová P
Klin Onkol 2019 Summer;32(Supplementum2):97-108. doi: 10.14735/amko2019S97. PMID: 31409085
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM
Hum Mutat 2008 Jun;29(6):852-60. doi: 10.1002/humu.20735. PMID: 18383312
Mutational targets in colorectal cancer cells with microsatellite instability.
Bertholon J, Wang Q, Galmarini CM, Puisieux A
Fam Cancer 2006;5(1):29-34. doi: 10.1007/s10689-005-2573-5. PMID: 16528606
Hereditary renal cancers.
Choyke PL, Glenn GM, Walther MM, Zbar B, Linehan WM
Radiology 2003 Jan;226(1):33-46. doi: 10.1148/radiol.2261011296. PMID: 12511666
Hereditary nonpolyposis colon cancer.
Cavalieri RJ, Franklin B
Am J Nurs 1998 Oct;98(10):42-3. PMID: 9803219

Therapy

Aspirin in gastrointestinal oncology: new data on an old friend.
Langley RE, Rothwell PM
Curr Opin Oncol 2014 Jul;26(4):441-7. doi: 10.1097/CCO.0000000000000098. PMID: 24840525
A contemporary review of uterine cancer management.
Carter J
Aust N Z J Obstet Gynaecol 2013 Dec;53(6):517-24. Epub 2013 Jul 6 doi: 10.1111/ajo.12109. PMID: 23829412
Therapeutic targeting of the DNA mismatch repair pathway.
Martin SA, Lord CJ, Ashworth A
Clin Cancer Res 2010 Nov 1;16(21):5107-13. Epub 2010 Sep 7 doi: 10.1158/1078-0432.CCR-10-0821. PMID: 20823149
Successful pregnancy after hysteroscopic removal of grade I endometrial carcinoma in a young woman with Lynch syndrome.
Sparac V, Ujević B, Ujević M, Pagon-Belina Z, Marton U
Int J Gynecol Cancer 2006 Jan-Feb;16 Suppl 1:442-5. doi: 10.1111/j.1525-1438.2006.00219.x. PMID: 16515642
Morphogenics as a tool for target discovery and drug development.
Nicolaides NC, Ebel W, Kline B, Chao Q, Routhier E, Sass PM, Grasso L
Ann N Y Acad Sci 2005 Nov;1059:86-96. doi: 10.1196/annals.1339.029. PMID: 16382047

Prognosis

The Role of the Transforming Growth Factor-β Signaling Pathway in Gastrointestinal Cancers.
Matsuoka T, Yashiro M
Biomolecules 2023 Oct 19;13(10) doi: 10.3390/biom13101551. PMID: 37892233Free PMC Article
Management of endometrial precancers.
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM
Hum Mutat 2008 Jun;29(6):852-60. doi: 10.1002/humu.20735. PMID: 18383312
Mutational targets in colorectal cancer cells with microsatellite instability.
Bertholon J, Wang Q, Galmarini CM, Puisieux A
Fam Cancer 2006;5(1):29-34. doi: 10.1007/s10689-005-2573-5. PMID: 16528606
Hereditary ovarian carcinoma.
Gallion HH, Smith SA
Semin Surg Oncol 1994 Jul-Aug;10(4):249-54. doi: 10.1002/ssu.2980100404. PMID: 8091066

Clinical prediction guides

Aspirin in gastrointestinal oncology: new data on an old friend.
Langley RE, Rothwell PM
Curr Opin Oncol 2014 Jul;26(4):441-7. doi: 10.1097/CCO.0000000000000098. PMID: 24840525
Management of endometrial precancers.
Trimble CL, Method M, Leitao M, Lu K, Ioffe O, Hampton M, Higgins R, Zaino R, Mutter GL; Society of Gynecologic Oncology Clinical Practice Committee
Obstet Gynecol 2012 Nov;120(5):1160-75. doi: 10.1097/aog.0b013e31826bb121. PMID: 23090535Free PMC Article
Accurate classification of MLH1/MSH2 missense variants with multivariate analysis of protein polymorphisms-mismatch repair (MAPP-MMR).
Chao EC, Velasquez JL, Witherspoon MS, Rozek LS, Peel D, Ng P, Gruber SB, Watson P, Rennert G, Anton-Culver H, Lynch H, Lipkin SM
Hum Mutat 2008 Jun;29(6):852-60. doi: 10.1002/humu.20735. PMID: 18383312
Mutational targets in colorectal cancer cells with microsatellite instability.
Bertholon J, Wang Q, Galmarini CM, Puisieux A
Fam Cancer 2006;5(1):29-34. doi: 10.1007/s10689-005-2573-5. PMID: 16528606
Mechanisms underlying mismatch repair deficiencies in normal cells.
Moliaka YK, Cella M, Chudina AP, Kolesnikova TN, Terracciano L, Cathomas G, Bochkov NP, Buerstedde JM
Genes Chromosomes Cancer 1997 Nov;20(3):305-9. PMID: 9365839

Recent systematic reviews

Screening strategies for colorectal cancer: a systematic review of the evidence.
McLeod RS; Canadian Task Force on Preventive Health Care
Can J Gastroenterol 2001 Oct;15(10):647-60. doi: 10.1155/2001/284746. PMID: 11694901

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    Practice guidelines

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