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Stage II Chronic Lymphocytic Leukemia

MedGen UID:
167715
•Concept ID:
C0854803
•
Neoplastic Process
Synonyms: Chronic Lymphocytic Leukemia Stage II; CLL Stage II; Stage II Chronic Lymphocytic Leukemia- Modified Rai Staging System; Stage II CLL

Definition

Risk: Intermediate; Findings: Lymphocytosis, adenopathy, and enlarged spleen and/or liver; Survival (months): 72. (from AJCC 8th Ed.) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStage II Chronic Lymphocytic Leukemia

Professional guidelines

PubMed

Role of fludarabine as monotherapy in the treatment of chronic lymphocytic leukemia.
Leporrier M
Hematol J 2004;5 Suppl 1:S10-9. doi: 10.1038/sj.thj.6200387. PMID: 15079149
Acquired von Willebrand syndromes: clinical features, aetiology, pathophysiology, classification and management.
Michiels JJ, Budde U, van der Planken M, van Vliet HH, Schroyens W, Berneman Z
Best Pract Res Clin Haematol 2001 Jun;14(2):401-36. doi: 10.1053/beha.2001.0141. PMID: 11686107
Fludarabine phosphate in the treatment of chronic lymphocytic leukemia.
Keating MJ
Semin Oncol 1990 Oct;17(5 Suppl 8):49-62. PMID: 1699283

Recent clinical studies

Etiology

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Diagnosis

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Therapy

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

Clinical prediction guides

Coexistence of chronic myeloid leukemia and diffuse large B-cell lymphoma with antecedent chronic lymphocytic leukemia: a case report and review of the literature.
Abuelgasim KA, Rehan H, Alsubaie M, Al Atwi N, Al Balwi M, Alshieban S, Almughairi A
J Med Case Rep 2018 Mar 11;12(1):64. doi: 10.1186/s13256-018-1612-4. PMID: 29524963Free PMC Article

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