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Tumors are benign

MedGen UID:
1676714
•Concept ID:
C5195477
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumors are benign

Professional guidelines

PubMed

Treatment strategies for craniopharyngiomas.
Ottenhausen M, Rumalla K, La Corte E, Alalade A, Nair P, Forbes J, Ben Nsir A, Schwartz TH
J Neurosurg Sci 2019 Feb;63(1):83-87. Epub 2017 Sep 4 doi: 10.23736/S0390-5616.17.04171-6. PMID: 28869375
Pheochromocytoma and Paraganglioma: Genetics, Diagnosis, and Treatment.
Fishbein L
Hematol Oncol Clin North Am 2016 Feb;30(1):135-50. Epub 2015 Oct 23 doi: 10.1016/j.hoc.2015.09.006. PMID: 26614373
Vulvar sarcomas: Short guideline for histopathological recognition and clinical management. Part 1.
Chokoeva AA, Tchernev G, Cardoso JC, Patterson JW, Dechev I, Valkanov S, Zanardelli M, Lotti T, Wollina U
Int J Immunopathol Pharmacol 2015 Jun;28(2):168-77. Epub 2015 Mar 26 doi: 10.1177/0394632015576029. PMID: 25816394

Recent clinical studies

Etiology

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.
Elta GH, Enestvedt BK, Sauer BG, Lennon AM
Am J Gastroenterol 2018 Apr;113(4):464-479. Epub 2018 Feb 27 doi: 10.1038/ajg.2018.14. PMID: 29485131
Malignant Peripheral Nerve Sheath Tumor.
James AW, Shurell E, Singh A, Dry SM, Eilber FC
Surg Oncol Clin N Am 2016 Oct;25(4):789-802. doi: 10.1016/j.soc.2016.05.009. PMID: 27591499
Bone cysts: unicameral and aneurysmal bone cyst.
Mascard E, Gomez-Brouchet A, Lambot K
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S119-27. Epub 2015 Jan 8 doi: 10.1016/j.otsr.2014.06.031. PMID: 25579825

Diagnosis

Management of neurofibromatosis type 1-associated plexiform neurofibromas.
Fisher MJ, Blakeley JO, Weiss BD, Dombi E, Ahlawat S, Akshintala S, Belzberg AJ, Bornhorst M, Bredella MA, Cai W, Ferner RE, Gross AM, Harris GJ, Listernick R, Ly I, Martin S, Mautner VF, Salamon JM, Salerno KE, Spinner RJ, Staedtke V, Ullrich NJ, Upadhyaya M, Wolters PL, Yohay K, Widemann BC
Neuro Oncol 2022 Nov 2;24(11):1827-1844. doi: 10.1093/neuonc/noac146. PMID: 35657359Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Diagnostic Pathology of Tumors of Peripheral Nerve.
Belakhoua SM, Rodriguez FJ
Neurosurgery 2021 Feb 16;88(3):443-456. doi: 10.1093/neuros/nyab021. PMID: 33588442Free PMC Article
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Tumors and tumor-like lesions of peripheral nerves.
Woertler K
Semin Musculoskelet Radiol 2010 Nov;14(5):547-58. Epub 2010 Nov 11 doi: 10.1055/s-0030-1268073. PMID: 21072731

Therapy

The role of immune cell signatures in the pathogenesis of ovarian-related diseases: a causal inference based on Mendelian randomization.
Lu Y, Yao Y, Zhai S, Ni F, Wang J, Chen F, Zhang Y, Li H, Hu H, Zhang H, Yu B, Chen H, Huang X, Ding W, Lu D
Int J Surg 2024 Oct 1;110(10):6541-6550. doi: 10.1097/JS9.0000000000001814. PMID: 38884272Free PMC Article
Effectiveness of different treatments for odontogenic keratocyst: a network meta-analysis.
Al-Moraissi EA, Kaur A, Gomez RS, Ellis E 3rd
Int J Oral Maxillofac Surg 2023 Jan;52(1):32-43. Epub 2022 Sep 21 doi: 10.1016/j.ijom.2022.09.004. PMID: 36150944
How effective is 5-Fluorouracil as an adjuvant in the management of odontogenic keratocyst? A systematic review and meta-analysis.
Singh AK, Khanal N, Chaulagain R, Bhujel N, Singh RP
Br J Oral Maxillofac Surg 2022 Jul;60(6):746-754. Epub 2022 Feb 17 doi: 10.1016/j.bjoms.2022.02.001. PMID: 35314081
Neurofibromatosis type 1: a multidisciplinary approach to care.
Hirbe AC, Gutmann DH
Lancet Neurol 2014 Aug;13(8):834-43. doi: 10.1016/S1474-4422(14)70063-8. PMID: 25030515
Adnexal masses in pregnancy.
Schwartz N, Timor-Tritsch IE, Wang E
Clin Obstet Gynecol 2009 Dec;52(4):570-85. doi: 10.1097/GRF.0b013e3181bea9d7. PMID: 20393410

Prognosis

Diagnosis of neonatal neurofibromatosis type 1: a case report and review of the literature.
Zheng Q, Xia B, Zhao X, Wang R, Xie F, Pei N, Tao H, Ding T, Liu L
BMC Pediatr 2023 May 24;23(1):259. doi: 10.1186/s12887-023-04077-z. PMID: 37226143Free PMC Article
Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment.
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N
JCI Insight 2022 Sep 22;7(18) doi: 10.1172/jci.insight.154513. PMID: 36134665Free PMC Article
Odontogenic Cysts and Neoplasms.
Bilodeau EA, Collins BM
Surg Pathol Clin 2017 Mar;10(1):177-222. Epub 2016 Dec 29 doi: 10.1016/j.path.2016.10.006. PMID: 28153133
Pancreatic Cysts.
Meagher T, Armuss A
J Insur Med 2016;46(2):60-65. doi: 10.17849/0743-6661-46.2.60. PMID: 28326875
Bone cysts: unicameral and aneurysmal bone cyst.
Mascard E, Gomez-Brouchet A, Lambot K
Orthop Traumatol Surg Res 2015 Feb;101(1 Suppl):S119-27. Epub 2015 Jan 8 doi: 10.1016/j.otsr.2014.06.031. PMID: 25579825

Clinical prediction guides

Multiple Nf1 Schwann cell populations reprogram the plexiform neurofibroma tumor microenvironment.
Kershner LJ, Choi K, Wu J, Zhang X, Perrino M, Salomonis N, Shern JF, Ratner N
JCI Insight 2022 Sep 22;7(18) doi: 10.1172/jci.insight.154513. PMID: 36134665Free PMC Article
Primary Intrabulbar Neurofibroma.
Furdová A, Babál P
Cesk Slov Oftalmol 2020 Spring;76(2):62-67. doi: 10.31348/2020/13. PMID: 33126800
The NF1 somatic mutational landscape in sporadic human cancers.
Philpott C, Tovell H, Frayling IM, Cooper DN, Upadhyaya M
Hum Genomics 2017 Jun 21;11(1):13. doi: 10.1186/s40246-017-0109-3. PMID: 28637487Free PMC Article
Plexiform schwannoma.
Megahed M
Am J Dermatopathol 1994 Jun;16(3):288-93. doi: 10.1097/00000372-199406000-00011. PMID: 7943637
Cervical thymic cyst.
Sanusi ID, Carrington PR, Adams DN
Arch Dermatol 1982 Feb;118(2):122-4. PMID: 6800306

Recent systematic reviews

Management of phyllodes tumor: A systematic review and meta-analysis of real-world evidence.
Yu CY, Huang TW, Tam KW
Int J Surg 2022 Nov;107:106969. Epub 2022 Oct 31 doi: 10.1016/j.ijsu.2022.106969. PMID: 36328344
Molecular Insights in Uterine Leiomyosarcoma: A Systematic Review.
Sparić R, Andjić M, Babović I, Nejković L, Mitrović M, Štulić J, Pupovac M, Tinelli A
Int J Mol Sci 2022 Aug 27;23(17) doi: 10.3390/ijms23179728. PMID: 36077127Free PMC Article
Malignant phyllodes tumor of the breast: a systematic review.
Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED
Pathologica 2022 Apr;114(2):111-120. Epub 2022 Apr 13 doi: 10.32074/1591-951X-754. PMID: 35414723Free PMC Article
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Headache in Ruptured Intracranial Dermoid Cysts.
Tolebeyan AS, Kuruvilla DE
Curr Pain Headache Rep 2020 May 29;24(7):31. doi: 10.1007/s11916-020-00863-x. PMID: 32472229

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