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Unresectable Intrahepatic Cholangiocarcinoma

MedGen UID:
1664280
Concept ID:
C4725028
Neoplastic Process

Definition

Intrahepatic cholangiocarcinoma that is not amenable to surgical removal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Intrahepatic Cholangiocarcinoma

Professional guidelines

PubMed

Liu D, Wang J, Ma Z, Zhang N, Zhao Y, Yang X, Wen Z, Xie H
Cardiovasc Intervent Radiol 2022 Aug;45(8):1092-1101. Epub 2022 May 19 doi: 10.1007/s00270-022-03108-z. PMID: 35588011
Aliberti C, Carandina R, Sarti D, Pizzirani E, Ramondo G, Mulazzani L, Mattioli GM, Fiorentini G
Anticancer Res 2017 Apr;37(4):1859-1863. doi: 10.21873/anticanres.11522. PMID: 28373452
Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS
Eur J Surg Oncol 2015 Jan;41(1):120-7. Epub 2014 Oct 7 doi: 10.1016/j.ejso.2014.09.007. PMID: 25449754Free PMC Article

Recent clinical studies

Etiology

Soares KC, Jolissaint JS, McIntyre SM, Seier KP, Gönen M, Sigel C, Nasar N, Cercek A, Harding JJ, Kemeny NE, Connell LC, Koerkamp BG, Balachandran VP, D'Angelica MI, Drebin JA, Kingham TP, Wei AC, Jarnagin WR
Cancer Med 2023 Jun;12(11):12272-12284. Epub 2023 Apr 16 doi: 10.1002/cam4.5925. PMID: 37062071Free PMC Article
Gupta AN, Gordon AC, Gabr A, Kalyan A, Kircher SM, Mahalingam D, Mulcahy MF, Merkow RP, Yang AD, Bentrem DJ, Caicedo-Ramirez JC, Riaz A, Thornburg B, Desai K, Sato KT, Hohlastos ES, Kulik L, Benson AB, Salem R, Lewandowski RJ
Cardiovasc Intervent Radiol 2022 Aug;45(8):1117-1128. Epub 2022 Jun 22 doi: 10.1007/s00270-022-03183-2. PMID: 35732931
Holster JJ, El Hassnaoui M, Franssen S, IJzermans JNM, de Jonge J, Mostert B, Polak WG, de Wilde RF, Homs MYV, Groot Koerkamp B
Ann Surg Oncol 2022 Sep;29(9):5528-5538. Epub 2022 Mar 16 doi: 10.1245/s10434-022-11439-x. PMID: 35294656Free PMC Article
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272
Hong K, Geschwind JF
Semin Oncol 2010 Apr;37(2):110-7. doi: 10.1053/j.seminoncol.2010.03.002. PMID: 20494703

Diagnosis

Maspero M, Sposito C, Bongini MA, Cascella T, Flores M, Maccauro M, Chiesa C, Niger M, Pietrantonio F, Leoncini G, Bellia V, Bhoori S, Mazzaferro V
Transpl Int 2024;37:13641. Epub 2024 Oct 31 doi: 10.3389/ti.2024.13641. PMID: 39544321Free PMC Article
Jiang N, Zhang Z, Yin X, Qiu H, Yan W, Hao Y, Yang W, Li H, Xu A, Mu K
Radiol Med 2024 Apr;129(4):631-642. Epub 2024 Feb 15 doi: 10.1007/s11547-024-01781-3. PMID: 38355907
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Hu EY, Bhagavatula S, Shi A, Tuncali K, Levesque V, Shyn PB
J Vasc Interv Radiol 2023 Jun;34(6):1007-1014. Epub 2023 Feb 25 doi: 10.1016/j.jvir.2023.02.024. PMID: 36842534
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article

Therapy

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Thiels CA, D'Angelica MI
J Surg Oncol 2020 Jul;122(1):70-77. Epub 2020 Mar 25 doi: 10.1002/jso.25913. PMID: 32215927Free PMC Article
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article
Edeline J, Touchefeu Y, Guiu B, Farge O, Tougeron D, Baumgaertner I, Ayav A, Campillo-Gimenez B, Beuzit L, Pracht M, Lièvre A, Le Sourd S, Boudjema K, Rolland Y, Boucher E, Garin E
JAMA Oncol 2020 Jan 1;6(1):51-59. doi: 10.1001/jamaoncol.2019.3702. PMID: 31670746Free PMC Article
Hong K, Geschwind JF
Semin Oncol 2010 Apr;37(2):110-7. doi: 10.1053/j.seminoncol.2010.03.002. PMID: 20494703

Prognosis

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272
Cercek A, Boerner T, Tan BR, Chou JF, Gönen M, Boucher TM, Hauser HF, Do RKG, Lowery MA, Harding JJ, Varghese AM, Reidy-Lagunes D, Saltz L, Schultz N, Kingham TP, D'Angelica MI, DeMatteo RP, Drebin JA, Allen PJ, Balachandran VP, Lim KH, Sanchez-Vega F, Vachharajani N, Majella Doyle MB, Fields RC, Hawkins WG, Strasberg SM, Chapman WC, Diaz LA Jr, Kemeny NE, Jarnagin WR
JAMA Oncol 2020 Jan 1;6(1):60-67. doi: 10.1001/jamaoncol.2019.3718. PMID: 31670750Free PMC Article
Edeline J, Touchefeu Y, Guiu B, Farge O, Tougeron D, Baumgaertner I, Ayav A, Campillo-Gimenez B, Beuzit L, Pracht M, Lièvre A, Le Sourd S, Boudjema K, Rolland Y, Boucher E, Garin E
JAMA Oncol 2020 Jan 1;6(1):51-59. doi: 10.1001/jamaoncol.2019.3702. PMID: 31670746Free PMC Article

Clinical prediction guides

Lei Z, Ma W, Si A, Zhang Y, Yang F, Yu Q, Tang H, Xiao Q, Zhou J, Wang K, Tang Y, Han T, Yin G, Chen J, Liu X, Zhao H, Yu D, Luo T, Wang Q, Yan M, Mao X, Li J, Wang K, Li J, Zeng Y, Ding D, Chen T, Wu X, Xia Y, Wang K, Guo W, Zhu G, Gao S, Hüser N, Lau WY, Song T, Cheng S, Shen F, Cheng Z
Aliment Pharmacol Ther 2023 Sep;58(6):611-622. Epub 2023 Jun 22 doi: 10.1111/apt.17623. PMID: 37349908
Soares KC, Jolissaint JS, McIntyre SM, Seier KP, Gönen M, Sigel C, Nasar N, Cercek A, Harding JJ, Kemeny NE, Connell LC, Koerkamp BG, Balachandran VP, D'Angelica MI, Drebin JA, Kingham TP, Wei AC, Jarnagin WR
Cancer Med 2023 Jun;12(11):12272-12284. Epub 2023 Apr 16 doi: 10.1002/cam4.5925. PMID: 37062071Free PMC Article
Scott A, Wong P, Melstrom LG
Surgery 2023 Jul;174(1):113-115. Epub 2023 Mar 9 doi: 10.1016/j.surg.2023.01.019. PMID: 36906437
Liu D, Wang J, Ma Z, Zhang N, Zhao Y, Yang X, Wen Z, Xie H
Cardiovasc Intervent Radiol 2022 Aug;45(8):1092-1101. Epub 2022 May 19 doi: 10.1007/s00270-022-03108-z. PMID: 35588011
McMillan RR, Javle M, Kodali S, Saharia A, Mobley C, Heyne K, Hobeika MJ, Lunsford KE, Victor DW 3rd, Shetty A, McFadden RS, Abdelrahim M, Kaseb A, Divatia M, Yu N, Nolte Fong J, Moore LW, Nguyen DT, Graviss EA, Gaber AO, Vauthey JN, Ghobrial RM
Am J Transplant 2022 Mar;22(3):823-832. Epub 2021 Dec 27 doi: 10.1111/ajt.16906. PMID: 34856069

Recent systematic reviews

Holster JJ, El Hassnaoui M, Franssen S, IJzermans JNM, de Jonge J, Mostert B, Polak WG, de Wilde RF, Homs MYV, Groot Koerkamp B
Ann Surg Oncol 2022 Sep;29(9):5528-5538. Epub 2022 Mar 16 doi: 10.1245/s10434-022-11439-x. PMID: 35294656Free PMC Article
Schartz DA, Porter M, Schartz E, Kallas J, Gupta A, Butani D, Cantos A
J Vasc Interv Radiol 2022 Jun;33(6):679-686. Epub 2022 Feb 25 doi: 10.1016/j.jvir.2022.02.016. PMID: 35219834
Mosconi C, Solaini L, Vara G, Brandi N, Cappelli A, Modestino F, Cucchetti A, Golfieri R
Cardiovasc Intervent Radiol 2021 May;44(5):728-738. Epub 2021 Mar 11 doi: 10.1007/s00270-021-02800-w. PMID: 33709272
Han K, Ko HK, Kim KW, Won HJ, Shin YM, Kim PN
J Vasc Interv Radiol 2015 Jul;26(7):943-8. Epub 2015 Apr 18 doi: 10.1016/j.jvir.2015.02.024. PMID: 25899049
Al-Adra DP, Gill RS, Axford SJ, Shi X, Kneteman N, Liau SS
Eur J Surg Oncol 2015 Jan;41(1):120-7. Epub 2014 Oct 7 doi: 10.1016/j.ejso.2014.09.007. PMID: 25449754Free PMC Article

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