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Supratentorial Pleomorphic Xanthoastrocytoma

MedGen UID:
1660183
•Concept ID:
C4744526
•
Neoplastic Process

Definition

A pleomorphic xanthoastrocytoma that arises from the supratentorial region of the brain. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSupratentorial Pleomorphic Xanthoastrocytoma

Professional guidelines

PubMed

Clinical Features, Treatment and Outcome of Childhood Glial Tumors.
Kara B, Ertan K, Karabagli P, Karabagli H, Yavas G, Caglayan AO, Koksal Y
Turk Neurosurg 2022;32(1):135-142. doi: 10.5137/1019-5149.JTN.34801-21.2. PMID: 34751424
Low grade supratentorial astrocytomas: management and prognostic factors.
Kreth FW, Warnke PC, Ostertag CB
Cancer 1994 Dec 15;74(12):3247-8. doi: 10.1002/1097-0142(19941215)74:12<3247::aid-cncr2820741227>3.0.co;2-j. PMID: 7982190
Differential diagnosis of supratentorial cystic intracranial lesions by CT-scanning.
Verhagen IT, Zeilstra DJ, Go KG
Br J Neurosurg 1987;1(4):447-54. doi: 10.3109/02688698708999635. PMID: 2855826

Recent clinical studies

Etiology

Rare AGK-BRAF gene fusion in an adolescent with supratentorial pleomorphic xanthoastrocytoma.
Chau L, Nael A, Sato M, Crawford JR
BMJ Case Rep 2024 Jan 18;17(1) doi: 10.1136/bcr-2023-258878. PMID: 38238163Free PMC Article
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Subgrouping of gliomas on the basis of genetic profiles.
Hirose Y, Sasaki H, Abe M, Hattori N, Adachi K, Nishiyama Y, Nagahisa S, Hayashi T, Hasegawa M, Yoshida K
Brain Tumor Pathol 2013 Oct;30(4):203-8. Epub 2013 Apr 20 doi: 10.1007/s10014-013-0148-y. PMID: 23604523
STAT3 tyrosine phosphorylation influences survival in glioblastoma.
Birner P, Toumangelova-Uzeir K, Natchev S, Guentchev M
J Neurooncol 2010 Dec;100(3):339-43. Epub 2010 May 9 doi: 10.1007/s11060-010-0195-8. PMID: 20455003

Diagnosis

Supratentorial Tumors in Pediatric Patients.
Zamora C, Huisman TA, Izbudak I
Neuroimaging Clin N Am 2017 Feb;27(1):39-67. doi: 10.1016/j.nic.2016.08.003. PMID: 27889023
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article
Supratentorial low-grade diffuse astrocytoma: medical management.
Ajlan A, Recht L
Semin Oncol 2014 Aug;41(4):446-457. Epub 2014 Jul 1 doi: 10.1053/j.seminoncol.2014.06.013. PMID: 25173138
Subgrouping of gliomas on the basis of genetic profiles.
Hirose Y, Sasaki H, Abe M, Hattori N, Adachi K, Nishiyama Y, Nagahisa S, Hayashi T, Hasegawa M, Yoshida K
Brain Tumor Pathol 2013 Oct;30(4):203-8. Epub 2013 Apr 20 doi: 10.1007/s10014-013-0148-y. PMID: 23604523
Cerebellar pleomorphic xanthoastrocytoma: case report and literature review.
Hamlat A, Le Strat A, Guegan Y, Ben-Hassel M, Saikali S
Surg Neurol 2007 Jul;68(1):89-94; discussion 94-5. Epub 2007 May 29 doi: 10.1016/j.surneu.2006.08.064. PMID: 17537486

Therapy

Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial.
Todo T, Ito H, Ino Y, Ohtsu H, Ota Y, Shibahara J, Tanaka M
Nat Med 2022 Aug;28(8):1630-1639. Epub 2022 Jul 21 doi: 10.1038/s41591-022-01897-x. PMID: 35864254Free PMC Article
Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Supratentorial low-grade diffuse astrocytoma: medical management.
Ajlan A, Recht L
Semin Oncol 2014 Aug;41(4):446-457. Epub 2014 Jul 1 doi: 10.1053/j.seminoncol.2014.06.013. PMID: 25173138
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Combined modality therapy for intracranial tumors.
Bloom HJ
Cancer 1975 Jan;35(1):111-20. doi: 10.1002/1097-0142(197501)35:1<111::aid-cncr2820350116>3.0.co;2-#. PMID: 162849

Prognosis

Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
Supratentorial low-grade diffuse astrocytoma: medical management.
Ajlan A, Recht L
Semin Oncol 2014 Aug;41(4):446-457. Epub 2014 Jul 1 doi: 10.1053/j.seminoncol.2014.06.013. PMID: 25173138
Subgrouping of gliomas on the basis of genetic profiles.
Hirose Y, Sasaki H, Abe M, Hattori N, Adachi K, Nishiyama Y, Nagahisa S, Hayashi T, Hasegawa M, Yoshida K
Brain Tumor Pathol 2013 Oct;30(4):203-8. Epub 2013 Apr 20 doi: 10.1007/s10014-013-0148-y. PMID: 23604523
Supratentorial grade II astrocytoma: biological features and clinical course.
Wessels PH, Weber WE, Raven G, Ramaekers FC, Hopman AH, Twijnstra A
Lancet Neurol 2003 Jul;2(7):395-403. doi: 10.1016/s1474-4422(03)00434-4. PMID: 12849117
Pediatric glial tumors.
Cohen KJ, Broniscer A, Glod J
Curr Treat Options Oncol 2001 Dec;2(6):529-36. doi: 10.1007/s11864-001-0074-9. PMID: 12057098

Clinical prediction guides

Recurrent Glioblastoma Treated with Recombinant Poliovirus.
Desjardins A, Gromeier M, Herndon JE 2nd, Beaubier N, Bolognesi DP, Friedman AH, Friedman HS, McSherry F, Muscat AM, Nair S, Peters KB, Randazzo D, Sampson JH, Vlahovic G, Harrison WT, McLendon RE, Ashley D, Bigner DD
N Engl J Med 2018 Jul 12;379(2):150-161. Epub 2018 Jun 26 doi: 10.1056/NEJMoa1716435. PMID: 29943666Free PMC Article
IDH mutations may not preclude distant, trans-tentorial spread in gliomas: a case report and review of the literature.
Hong CS, Hsieh JK, Edwards NA, Ray-Chaudhury A, Zaghloul KA
World J Surg Oncol 2016 Feb 24;14:53. doi: 10.1186/s12957-016-0814-8. PMID: 26911558Free PMC Article
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastoma.
Chinot OL, Wick W, Mason W, Henriksson R, Saran F, Nishikawa R, Carpentier AF, Hoang-Xuan K, Kavan P, Cernea D, Brandes AA, Hilton M, Abrey L, Cloughesy T
N Engl J Med 2014 Feb 20;370(8):709-22. doi: 10.1056/NEJMoa1308345. PMID: 24552318
Aggressive behavior and anaplasia in pleomorphic xanthoastrocytoma: a plea for a revision of the current WHO classification.
Kahramancetin N, Tihan T
CNS Oncol 2013 Nov;2(6):523-30. doi: 10.2217/cns.13.56. PMID: 25054822Free PMC Article
Cerebellar pleomorphic xanthoastrocytoma: case report and literature review.
Hamlat A, Le Strat A, Guegan Y, Ben-Hassel M, Saikali S
Surg Neurol 2007 Jul;68(1):89-94; discussion 94-5. Epub 2007 May 29 doi: 10.1016/j.surneu.2006.08.064. PMID: 17537486

Recent systematic reviews

Evaluating efficacy and safety of laser interstitial thermal therapy in patients with newly diagnosed and recurrent glioblastoma: a systematic review and meta-analysis.
Rangwala HS, Shafique MA, Mustafa MS, Kumar R, Devi J, Rangwala BS, Ali SMS, Raja A, Iqbal J, Ali M, Haseeb A
Neurosurg Rev 2024 Nov 12;47(1):846. doi: 10.1007/s10143-024-03077-6. PMID: 39528836
Cerebellar glioblastoma in adults: a comparative single-center matched pair analysis and systematic review of the literature.
Lizunou Y, Potthoff AL, Schäfer N, Waha A, Borger V, Herrlinger U, Vatter H, Schuss P, Schneider M
J Cancer Res Clin Oncol 2024 Sep 28;150(9):432. doi: 10.1007/s00432-024-05959-0. PMID: 39340649Free PMC Article
The role of radiation therapy in treatment of adults with newly diagnosed glioblastoma multiforme: a systematic review and evidence-based clinical practice guideline update.
Ziu M, Kim BYS, Jiang W, Ryken T, Olson JJ
J Neurooncol 2020 Nov;150(2):215-267. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03612-7. PMID: 33215344
Cytoreductive surgery in the management of newly diagnosed glioblastoma in adults: a systematic review and evidence-based clinical practice guideline update.
Domino JS, Ormond DR, Germano IM, Sami M, Ryken TC, Olson JJ
J Neurooncol 2020 Nov;150(2):121-142. Epub 2020 Nov 19 doi: 10.1007/s11060-020-03606-5. PMID: 33215341
Association of the Extent of Resection With Survival in Glioblastoma: A Systematic Review and Meta-analysis.
Brown TJ, Brennan MC, Li M, Church EW, Brandmeir NJ, Rakszawski KL, Patel AS, Rizk EB, Suki D, Sawaya R, Glantz M
JAMA Oncol 2016 Nov 1;2(11):1460-1469. doi: 10.1001/jamaoncol.2016.1373. PMID: 27310651Free PMC Article

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