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Unresectable Thymic Carcinoma

MedGen UID:
1654331
•Concept ID:
C4724831
•
Neoplastic Process

Definition

A thymic carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Thymic Carcinoma

Professional guidelines

PubMed

Chemotherapy versus chemotherapy plus immune checkpoint inhibitors for the first-line treatment of unresectable thymic carcinoma: A multicenter retrospective study.
Zhang B, Liu Y, Chen Z, Chen J, Yu H, Li M, Ma S, Cheng C, Chen L
Int J Cancer 2024 Aug 15;155(4):710-718. Epub 2024 Apr 12 doi: 10.1002/ijc.34948. PMID: 38608177
Characteristics and outcome of systemic treatment for metastatic or unresectable thymic carcinoma: A single institution experience.
Ho IW, Pan YL, Lai JI, Liu CY
Thorac Cancer 2024 Feb;15(4):339-346. Epub 2023 Dec 27 doi: 10.1111/1759-7714.15198. PMID: 38149471Free PMC Article

Recent clinical studies

Etiology

Chemotherapy versus chemotherapy plus immune checkpoint inhibitors for the first-line treatment of unresectable thymic carcinoma: A multicenter retrospective study.
Zhang B, Liu Y, Chen Z, Chen J, Yu H, Li M, Ma S, Cheng C, Chen L
Int J Cancer 2024 Aug 15;155(4):710-718. Epub 2024 Apr 12 doi: 10.1002/ijc.34948. PMID: 38608177
Characteristics and outcome of systemic treatment for metastatic or unresectable thymic carcinoma: A single institution experience.
Ho IW, Pan YL, Lai JI, Liu CY
Thorac Cancer 2024 Feb;15(4):339-346. Epub 2023 Dec 27 doi: 10.1111/1759-7714.15198. PMID: 38149471Free PMC Article
Combination chemotherapy with doxorubicin, vincristine, cyclophosphamide, and platinum compounds for advanced thymic carcinoma.
Agatsuma T, Koizumi T, Kanda S, Ito M, Urushihata K, Yamamoto H, Hanaoka M, Kubo K
J Thorac Oncol 2011 Dec;6(12):2130-4. doi: 10.1097/JTO.0b013e31822e71c0. PMID: 21892103
Second-line chemotherapy of platinum compound plus CPT-11 following ADOC chemotherapy in advanced thymic carcinoma: analysis of seven cases.
Kanda S, Koizumi T, Komatsu Y, Yoshikawa S, Okada M, Hatayama O, Yasuo M, Tsushima K, Urushihata K, Kubo K, Sasabayashi M, Takamizawa A
Anticancer Res 2007 Jul-Aug;27(4C):3005-8. PMID: 17695487
Concurrent chemoradiotherapy for unresectable thymic carcinoma.
Chen YY, Huang CH, Tang Y, Eng HL
Chang Gung Med J 2004 Jul;27(7):515-22. PMID: 15508874

Diagnosis

Chemotherapy versus chemotherapy plus immune checkpoint inhibitors for the first-line treatment of unresectable thymic carcinoma: A multicenter retrospective study.
Zhang B, Liu Y, Chen Z, Chen J, Yu H, Li M, Ma S, Cheng C, Chen L
Int J Cancer 2024 Aug 15;155(4):710-718. Epub 2024 Apr 12 doi: 10.1002/ijc.34948. PMID: 38608177
A rare case of tumor-to-tumor metastasis from thymic carcinoma to an ovarian mature teratoma.
Sasada T, Shirakawa C, Tachikawa R, Yamashita D, Tomii K
Thorac Cancer 2024 Apr;15(11):934-937. Epub 2024 Mar 11 doi: 10.1111/1759-7714.15277. PMID: 38468427Free PMC Article
Successful resection after first-line lenvatinib therapy in an advanced thymic carcinoma.
Shimura M, Miura K, Koizumi T, Kanda S, Mishima S, Hara D, Matsuoka S, Eguchi T, Hamanaka K, Uehara T, Shimizu K
Thorac Cancer 2023 Jun;14(17):1640-1643. Epub 2023 May 2 doi: 10.1111/1759-7714.14913. PMID: 37132133Free PMC Article
Concurrent chemoradiotherapy for unresectable thymic carcinoma.
Chen YY, Huang CH, Tang Y, Eng HL
Chang Gung Med J 2004 Jul;27(7):515-22. PMID: 15508874

Therapy

Chemotherapy versus chemotherapy plus immune checkpoint inhibitors for the first-line treatment of unresectable thymic carcinoma: A multicenter retrospective study.
Zhang B, Liu Y, Chen Z, Chen J, Yu H, Li M, Ma S, Cheng C, Chen L
Int J Cancer 2024 Aug 15;155(4):710-718. Epub 2024 Apr 12 doi: 10.1002/ijc.34948. PMID: 38608177
Characteristics and outcome of systemic treatment for metastatic or unresectable thymic carcinoma: A single institution experience.
Ho IW, Pan YL, Lai JI, Liu CY
Thorac Cancer 2024 Feb;15(4):339-346. Epub 2023 Dec 27 doi: 10.1111/1759-7714.15198. PMID: 38149471Free PMC Article
Combination chemotherapy with doxorubicin, vincristine, cyclophosphamide, and platinum compounds for advanced thymic carcinoma.
Agatsuma T, Koizumi T, Kanda S, Ito M, Urushihata K, Yamamoto H, Hanaoka M, Kubo K
J Thorac Oncol 2011 Dec;6(12):2130-4. doi: 10.1097/JTO.0b013e31822e71c0. PMID: 21892103
Efficacy of chemotherapy with carboplatin and paclitaxel for unresectable thymic carcinoma.
Igawa S, Murakami H, Takahashi T, Nakamura Y, Tsuya A, Naito T, Kaira K, Ono A, Shukuya T, Tamiya A, Endo M, Yamamoto N
Lung Cancer 2010 Feb;67(2):194-7. Epub 2009 May 5 doi: 10.1016/j.lungcan.2009.03.031. PMID: 19409644
Concurrent chemoradiotherapy for unresectable thymic carcinoma.
Chen YY, Huang CH, Tang Y, Eng HL
Chang Gung Med J 2004 Jul;27(7):515-22. PMID: 15508874

Prognosis

Chemotherapy versus chemotherapy plus immune checkpoint inhibitors for the first-line treatment of unresectable thymic carcinoma: A multicenter retrospective study.
Zhang B, Liu Y, Chen Z, Chen J, Yu H, Li M, Ma S, Cheng C, Chen L
Int J Cancer 2024 Aug 15;155(4):710-718. Epub 2024 Apr 12 doi: 10.1002/ijc.34948. PMID: 38608177
Characteristics and outcome of systemic treatment for metastatic or unresectable thymic carcinoma: A single institution experience.
Ho IW, Pan YL, Lai JI, Liu CY
Thorac Cancer 2024 Feb;15(4):339-346. Epub 2023 Dec 27 doi: 10.1111/1759-7714.15198. PMID: 38149471Free PMC Article
Second-line chemotherapy of platinum compound plus CPT-11 following ADOC chemotherapy in advanced thymic carcinoma: analysis of seven cases.
Kanda S, Koizumi T, Komatsu Y, Yoshikawa S, Okada M, Hatayama O, Yasuo M, Tsushima K, Urushihata K, Kubo K, Sasabayashi M, Takamizawa A
Anticancer Res 2007 Jul-Aug;27(4C):3005-8. PMID: 17695487
Concurrent chemoradiotherapy for unresectable thymic carcinoma.
Chen YY, Huang CH, Tang Y, Eng HL
Chang Gung Med J 2004 Jul;27(7):515-22. PMID: 15508874
Platinum-based chemotherapy with or without thoracic radiation therapy in patients with unresectable thymic carcinoma.
Nakamura Y, Kunitoh H, Kubota K, Sekine I, Shinkai T, Tamura T, Kodama T, Sumi M, Kohno S, Saijo N
Jpn J Clin Oncol 2000 Sep;30(9):385-8. doi: 10.1093/jjco/hyd108. PMID: 11095135

Clinical prediction guides

A rare case of tumor-to-tumor metastasis from thymic carcinoma to an ovarian mature teratoma.
Sasada T, Shirakawa C, Tachikawa R, Yamashita D, Tomii K
Thorac Cancer 2024 Apr;15(11):934-937. Epub 2024 Mar 11 doi: 10.1111/1759-7714.15277. PMID: 38468427Free PMC Article
Efficacy of chemotherapy with carboplatin and paclitaxel for unresectable thymic carcinoma.
Igawa S, Murakami H, Takahashi T, Nakamura Y, Tsuya A, Naito T, Kaira K, Ono A, Shukuya T, Tamiya A, Endo M, Yamamoto N
Lung Cancer 2010 Feb;67(2):194-7. Epub 2009 May 5 doi: 10.1016/j.lungcan.2009.03.031. PMID: 19409644
Second-line chemotherapy of platinum compound plus CPT-11 following ADOC chemotherapy in advanced thymic carcinoma: analysis of seven cases.
Kanda S, Koizumi T, Komatsu Y, Yoshikawa S, Okada M, Hatayama O, Yasuo M, Tsushima K, Urushihata K, Kubo K, Sasabayashi M, Takamizawa A
Anticancer Res 2007 Jul-Aug;27(4C):3005-8. PMID: 17695487

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