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Ovarian seromucinous carcinoma

MedGen UID:
1651770
•Concept ID:
C0279392
•
Neoplastic Process
Synonyms: malignant ovarian mixed epithelial neoplasm; malignant ovarian mixed epithelial tumor; malignant ovarian mixed epithelial tumour; mixed epithelial carcinoma of ovary; mixed epithelial carcinoma of the ovary; ovarian mixed epithelial carcinoma; Ovarian Seromucinous Carcinoma; ovarian seromucinous carcinoma; ovarian Seromucinous carcinoma
 
Monarch Initiative: MONDO:0004032

Definition

A malignant mixed epithelial neoplasm that arises from the ovary and is composed predominantly of serous and endocervical-type mucinous cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian seromucinous carcinoma

Professional guidelines

PubMed

Magnetic resonance imaging findings of cystic ovarian tumors: major differential diagnoses in five types frequently encountered in daily clinical practice.
Ohya A, Fujinaga Y
Jpn J Radiol 2022 Dec;40(12):1213-1234. Epub 2022 Aug 2 doi: 10.1007/s11604-022-01321-x. PMID: 35916971Free PMC Article
Diagnostic criteria and behavior of ovarian seromucinous (endocervical-type mucinous and mixed cell-type) tumors: atypical proliferative (borderline) tumors, intraepithelial, microinvasive, and invasive carcinomas.
Shappell HW, Riopel MA, Smith Sehdev AE, Ronnett BM, Kurman RJ
Am J Surg Pathol 2002 Dec;26(12):1529-41. doi: 10.1097/00000478-200212000-00001. PMID: 12459620

Recent clinical studies

Etiology

PAX2, PAX8, and PR are correlated with ovarian seromucinous borderline tumor with endometriosis.
Yun BS, Won S, Kim JH, Lee N, Kim M, Kim MK, Kim ML, Jung YW, Kim JY, Seong SJ, Shin E
J Ovarian Res 2022 Apr 6;15(1):41. doi: 10.1186/s13048-022-00975-5. PMID: 35387670Free PMC Article

Diagnosis

Ovarian seromucinous carcinoma: an independent epithelial ovarian cancer?
Hu Y, Fu K, Liu H, He Q, Qiu X, Yang W, Zhang Y
J Ovarian Res 2023 Jan 20;16(1):18. doi: 10.1186/s13048-023-01100-w. PMID: 36670456Free PMC Article
Synchronous Occurrence of Ovarian Seromucinous Carcinoma and Endometrial Mucinous Carcinoma: A Case Report.
Urakawa R, Harada H, Tohyama A, Aoyama Y, Kinjo Y, Hoshino K, Ueda T, Kagami S, Tsukamoto J, Aoki T, Iwamura R, Hisaoka M, Matsuura Y, Yoshino K
J UOEH 2021;43(2):235-242. doi: 10.7888/juoeh.43.235. PMID: 34092768
Seromucinous component in endometrioid endometrial carcinoma as a histological predictor of prognosis.
Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa T, Tsuda H, Furuya K
J Gynecol Oncol 2018 Mar;29(2):e20. Epub 2017 Dec 22 doi: 10.3802/jgo.2018.29.e20. PMID: 29400013Free PMC Article

Prognosis

Ovarian seromucinous carcinoma: an independent epithelial ovarian cancer?
Hu Y, Fu K, Liu H, He Q, Qiu X, Yang W, Zhang Y
J Ovarian Res 2023 Jan 20;16(1):18. doi: 10.1186/s13048-023-01100-w. PMID: 36670456Free PMC Article
Synchronous Occurrence of Ovarian Seromucinous Carcinoma and Endometrial Mucinous Carcinoma: A Case Report.
Urakawa R, Harada H, Tohyama A, Aoyama Y, Kinjo Y, Hoshino K, Ueda T, Kagami S, Tsukamoto J, Aoki T, Iwamura R, Hisaoka M, Matsuura Y, Yoshino K
J UOEH 2021;43(2):235-242. doi: 10.7888/juoeh.43.235. PMID: 34092768
Seromucinous component in endometrioid endometrial carcinoma as a histological predictor of prognosis.
Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa T, Tsuda H, Furuya K
J Gynecol Oncol 2018 Mar;29(2):e20. Epub 2017 Dec 22 doi: 10.3802/jgo.2018.29.e20. PMID: 29400013Free PMC Article

Clinical prediction guides

Seromucinous component in endometrioid endometrial carcinoma as a histological predictor of prognosis.
Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa T, Tsuda H, Furuya K
J Gynecol Oncol 2018 Mar;29(2):e20. Epub 2017 Dec 22 doi: 10.3802/jgo.2018.29.e20. PMID: 29400013Free PMC Article

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