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Abnormal myeloid cell morphology

MedGen UID:
1644538
Concept ID:
C4703725
Finding
HPO: HP:0020047

Definition

Any structural anomaly of a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal myeloid cell morphology

Professional guidelines

PubMed

Patnaik MM, Tefferi A
Am J Hematol 2024 Jun;99(6):1142-1165. Epub 2024 Mar 7 doi: 10.1002/ajh.27271. PMID: 38450850Free PMC Article
Pardanani A
Am J Hematol 2021 Apr 1;96(4):508-525. Epub 2021 Feb 21 doi: 10.1002/ajh.26118. PMID: 33524167
Patnaik MM, Tefferi A
Am J Hematol 2021 Mar 1;96(3):379-394. Epub 2021 Jan 28 doi: 10.1002/ajh.26090. PMID: 33428785

Recent clinical studies

Etiology

Calissendorff J, Juhlin CC, Sundin A, Bancos I, Falhammar H
Lancet Diabetes Endocrinol 2021 Nov;9(11):767-775. Epub 2021 Aug 24 doi: 10.1016/S2213-8587(21)00178-9. PMID: 34450092Free PMC Article
Wu X, Liu Y, Jin S, Wang M, Jiao Y, Yang B, Lu X, Ji X, Fei Y, Yang H, Zhao L, Chen H, Zhang Y, Li H, Lipsky PE, Tsokos GC, Bai F, Zhang X
Nat Commun 2021 Aug 17;12(1):4977. doi: 10.1038/s41467-021-25246-7. PMID: 34404786Free PMC Article
Wang WM, Jin HZ
J Immunol Res 2020;2020:3709749. Epub 2020 Jun 5 doi: 10.1155/2020/3709749. PMID: 32587871Free PMC Article
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I
Curr Hematol Malig Rep 2016 Oct;11(5):333-41. doi: 10.1007/s11899-016-0338-x. PMID: 27510823Free PMC Article
Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, Bloomfield CD, Estey E, Burnett A, Cornelissen JJ, Scheinberg DA, Bouscary D, Linch DC
Nat Rev Dis Primers 2016 Mar 10;2:16010. doi: 10.1038/nrdp.2016.10. PMID: 27159408

Diagnosis

Snoderly HT, Boone BA, Bennewitz MF
Breast Cancer Res 2019 Dec 18;21(1):145. doi: 10.1186/s13058-019-1237-6. PMID: 31852512Free PMC Article
Bhatnagar N, Nizery L, Tunstall O, Vyas P, Roberts I
Curr Hematol Malig Rep 2016 Oct;11(5):333-41. doi: 10.1007/s11899-016-0338-x. PMID: 27510823Free PMC Article
Khwaja A, Bjorkholm M, Gale RE, Levine RL, Jordan CT, Ehninger G, Bloomfield CD, Estey E, Burnett A, Cornelissen JJ, Scheinberg DA, Bouscary D, Linch DC
Nat Rev Dis Primers 2016 Mar 10;2:16010. doi: 10.1038/nrdp.2016.10. PMID: 27159408
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW
Blood 2016 May 19;127(20):2391-405. Epub 2016 Apr 11 doi: 10.1182/blood-2016-03-643544. PMID: 27069254
Razera F, Olm GS, Bonamigo RR
An Bras Dermatol 2011 Mar-Apr;86(2):195-209; quiz 210-1. doi: 10.1590/s0365-05962011000200001. PMID: 21603801

Therapy

Zhao D, Wang Y, Wu S, Ji X, Gong K, Zheng H, Zhu M
Front Immunol 2024;15:1383263. Epub 2024 Apr 26 doi: 10.3389/fimmu.2024.1383263. PMID: 38736879Free PMC Article
Li W, Lin A, Qi L, Lv X, Yan S, Xue J, Mu N
Front Immunol 2023;14:1128301. Epub 2023 Apr 17 doi: 10.3389/fimmu.2023.1128301. PMID: 37138868Free PMC Article
Almosailleakh M, Schwaller J
Int J Mol Sci 2019 Jan 21;20(2) doi: 10.3390/ijms20020453. PMID: 30669675Free PMC Article
Kaplan AP, Giménez-Arnau AM, Saini SS
Allergy 2017 Apr;72(4):519-533. Epub 2017 Jan 4 doi: 10.1111/all.13083. PMID: 27861988Free PMC Article
Craig VJ, Zhang L, Hagood JS, Owen CA
Am J Respir Cell Mol Biol 2015 Nov;53(5):585-600. doi: 10.1165/rcmb.2015-0020TR. PMID: 26121236Free PMC Article

Prognosis

Guimarães GR, Maklouf GR, Teixeira CE, de Oliveira Santos L, Tessarollo NG, de Toledo NE, Serain AF, de Lanna CA, Pretti MA, da Cruz JGV, Falchetti M, Dimas MM, Filgueiras IS, Cabral-Marques O, Ramos RN, de Macedo FC, Rodrigues FR, Bastos NC, da Silva JL, Lummertz da Rocha E, Chaves CBP, de Melo AC, Moraes-Vieira PMM, Mori MA, Boroni M
Nat Commun 2024 Jul 7;15(1):5694. doi: 10.1038/s41467-024-49916-4. PMID: 38972873Free PMC Article
Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD, Jacobs A, Windhager J, Silina K, van den Broek M, Dedes KJ, Rodríguez Martínez M, Weber WP, Bodenmiller B
Cell 2019 May 16;177(5):1330-1345.e18. Epub 2019 Apr 11 doi: 10.1016/j.cell.2019.03.005. PMID: 30982598Free PMC Article
Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW
Blood 2016 May 19;127(20):2391-405. Epub 2016 Apr 11 doi: 10.1182/blood-2016-03-643544. PMID: 27069254
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, Golub TR, Armstrong SA
Nature 2006 Aug 17;442(7104):818-22. Epub 2006 Jul 16 doi: 10.1038/nature04980. PMID: 16862118
Grignani F
Crit Rev Oncol Hematol 1985;4(1):31-66. PMID: 3902263

Clinical prediction guides

Guimarães GR, Maklouf GR, Teixeira CE, de Oliveira Santos L, Tessarollo NG, de Toledo NE, Serain AF, de Lanna CA, Pretti MA, da Cruz JGV, Falchetti M, Dimas MM, Filgueiras IS, Cabral-Marques O, Ramos RN, de Macedo FC, Rodrigues FR, Bastos NC, da Silva JL, Lummertz da Rocha E, Chaves CBP, de Melo AC, Moraes-Vieira PMM, Mori MA, Boroni M
Nat Commun 2024 Jul 7;15(1):5694. doi: 10.1038/s41467-024-49916-4. PMID: 38972873Free PMC Article
Liu YY, Liu YK, Hu WT, Tang LL, Sheng YR, Wei CY, Li MQ, Zhu XY
Reproduction 2019 Sep;158(3):257-266. doi: 10.1530/REP-19-0028. PMID: 31299634
Ng SW, Mitchell A, Kennedy JA, Chen WC, McLeod J, Ibrahimova N, Arruda A, Popescu A, Gupta V, Schimmer AD, Schuh AC, Yee KW, Bullinger L, Herold T, Görlich D, Büchner T, Hiddemann W, Berdel WE, Wörmann B, Cheok M, Preudhomme C, Dombret H, Metzeler K, Buske C, Löwenberg B, Valk PJ, Zandstra PW, Minden MD, Dick JE, Wang JC
Nature 2016 Dec 15;540(7633):433-437. Epub 2016 Dec 7 doi: 10.1038/nature20598. PMID: 27926740
Popovic PJ, Zeh HJ 3rd, Ochoa JB
J Nutr 2007 Jun;137(6 Suppl 2):1681S-1686S. doi: 10.1093/jn/137.6.1681S. PMID: 17513447
Drummond MW, Balabanov S, Holyoake TL, Brummendorf TH
Stem Cells 2007 Aug;25(8):1853-61. Epub 2007 May 17 doi: 10.1634/stemcells.2007-0057. PMID: 17510216

Recent systematic reviews

Zhao J, Dong Y, Zhang Y, Wang J, Wang Z
Adv Drug Deliv Rev 2022 Dec;191:114585. Epub 2022 Oct 21 doi: 10.1016/j.addr.2022.114585. PMID: 36273512
Shi Y, Wang C
Clin Immunol 2022 Apr;237:108982. Epub 2022 Mar 17 doi: 10.1016/j.clim.2022.108982. PMID: 35307610
Scappaticcio L, Maiorino MI, Maio A, Esposito K, Bellastella G
Clin Endocrinol (Oxf) 2021 Mar;94(3):473-483. Epub 2020 Sep 1 doi: 10.1111/cen.14313. PMID: 32799342
Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956
Satgé D, Nishi M, Sirvent N, Vekemans M
Am J Med Genet C Semin Med Genet 2016 Sep;172(3):296-306. Epub 2016 Jul 30 doi: 10.1002/ajmg.c.31511. PMID: 27474103

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