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Grade 2 Headache, CTCAE

MedGen UID:
1637625
•Concept ID:
C4688533
•
Finding

Definition

Moderate pain; limiting instrumental ADL [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGrade 2 Headache, CTCAE

Professional guidelines

PubMed

Treatment tolerance of particle therapy in pediatric patients.
Rieber JG, Kessel KA, Witt O, Behnisch W, Kulozik AE, Debus J, Combs SE
Acta Oncol 2015 Jul;54(7):1049-55. Epub 2015 Jan 23 doi: 10.3109/0284186X.2014.998273. PMID: 25615893

Recent clinical studies

Etiology

Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients.
Ahmadvand M, Barough MS, Barkhordar M, Faridfar A, Ghaderi A, Jalaeikhoo H, Rajaienejad M, Majidzadeh K, Ghavamzadeh A, Sarrami-Forooshani R
BMC Cancer 2023 Nov 10;23(1):1090. doi: 10.1186/s12885-023-11610-x. PMID: 37950209Free PMC Article
Surgically targeted radiation therapy (STaRT) for recurrent brain metastases: Initial clinical experience.
Kutuk T, Tolakanahalli R, Chaswal V, Yarlagadda S, Herrera R, Appel H, La Rosa A, Mishra V, Wieczorek DJJ, McDermott MW, Siomin V, Mehta MP, Odia Y, Gutierrez AN, Kotecha R
Brachytherapy 2023 Nov-Dec;22(6):872-881. Epub 2023 Sep 16 doi: 10.1016/j.brachy.2023.08.002. PMID: 37722990
Safety, immunogenecity and effectiveness of ChAdOx1 nCoV-19 vaccine during the second wave of pandemic in India: a real-world study.
Chavan P, Dey R, Castelino R, Kamble A, Poladia P, Bagal R, Jadhav M, Shirsat A, Chavan A, Dhumal S, Kumar S, Krishnamurty MN, Bhat V, Bhattacharjee A, Gota V
Drug Metab Pers Ther 2023 Sep 1;38(3):227-236. Epub 2023 Apr 26 doi: 10.1515/dmpt-2022-0150. PMID: 37098129
Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects.
Wu J, Xu H, Li H, Ma L, Chen J, Yuan F, Sheng L, Liu C, Chen W, Li X
Drug Des Devel Ther 2023;17:761-769. Epub 2023 Mar 10 doi: 10.2147/DDDT.S388846. PMID: 36925997Free PMC Article
Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article

Diagnosis

Comparison between Reirradiation by Stereotactic Body Radiation Therapy and Moderately Hypofractionated Radiotherapy in Combination with Temozolomide for Treatment of Recurrent High Grade Glioma.
Saad E, Abdelwahed M, Moussa R, Abdulla M
Asian Pac J Cancer Prev 2024 Jul 1;25(7):2499-2507. doi: 10.31557/APJCP.2024.25.7.2499. PMID: 39068585Free PMC Article
Investigating the safety and feasibility of osteopathic manipulative medicine in hospitalized children and adolescent young adults with cancer.
Belsky JA, Brown AM
J Osteopath Med 2024 Sep 1;124(9):399-406. Epub 2024 Apr 29 doi: 10.1515/jom-2024-0013. PMID: 38669608
Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article
Infusion reactions are common after high-dose carmustine in BEAM chemotherapy and are not reduced by lengthening the time of administration.
Perreault S, Baker J, Medoff E, Pratt K, Foss F, Isufi I, Seropian S, Cooper DL
Support Care Cancer 2017 Jan;25(1):205-208. Epub 2016 Sep 10 doi: 10.1007/s00520-016-3399-4. PMID: 27614867
Brain injury after proton therapy or carbon ion therapy for head-and-neck cancer and skull base tumors.
Miyawaki D, Murakami M, Demizu Y, Sasaki R, Niwa Y, Terashima K, Nishimura H, Hishikawa Y, Sugimura K
Int J Radiat Oncol Biol Phys 2009 Oct 1;75(2):378-84. doi: 10.1016/j.ijrobp.2008.12.092. PMID: 19735866

Therapy

Comparison between Reirradiation by Stereotactic Body Radiation Therapy and Moderately Hypofractionated Radiotherapy in Combination with Temozolomide for Treatment of Recurrent High Grade Glioma.
Saad E, Abdelwahed M, Moussa R, Abdulla M
Asian Pac J Cancer Prev 2024 Jul 1;25(7):2499-2507. doi: 10.31557/APJCP.2024.25.7.2499. PMID: 39068585Free PMC Article
Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients.
Ahmadvand M, Barough MS, Barkhordar M, Faridfar A, Ghaderi A, Jalaeikhoo H, Rajaienejad M, Majidzadeh K, Ghavamzadeh A, Sarrami-Forooshani R
BMC Cancer 2023 Nov 10;23(1):1090. doi: 10.1186/s12885-023-11610-x. PMID: 37950209Free PMC Article
Surgically targeted radiation therapy (STaRT) for recurrent brain metastases: Initial clinical experience.
Kutuk T, Tolakanahalli R, Chaswal V, Yarlagadda S, Herrera R, Appel H, La Rosa A, Mishra V, Wieczorek DJJ, McDermott MW, Siomin V, Mehta MP, Odia Y, Gutierrez AN, Kotecha R
Brachytherapy 2023 Nov-Dec;22(6):872-881. Epub 2023 Sep 16 doi: 10.1016/j.brachy.2023.08.002. PMID: 37722990
Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects.
Wu J, Xu H, Li H, Ma L, Chen J, Yuan F, Sheng L, Liu C, Chen W, Li X
Drug Des Devel Ther 2023;17:761-769. Epub 2023 Mar 10 doi: 10.2147/DDDT.S388846. PMID: 36925997Free PMC Article
Brain injury after proton therapy or carbon ion therapy for head-and-neck cancer and skull base tumors.
Miyawaki D, Murakami M, Demizu Y, Sasaki R, Niwa Y, Terashima K, Nishimura H, Hishikawa Y, Sugimura K
Int J Radiat Oncol Biol Phys 2009 Oct 1;75(2):378-84. doi: 10.1016/j.ijrobp.2008.12.092. PMID: 19735866

Prognosis

Comparison between Reirradiation by Stereotactic Body Radiation Therapy and Moderately Hypofractionated Radiotherapy in Combination with Temozolomide for Treatment of Recurrent High Grade Glioma.
Saad E, Abdelwahed M, Moussa R, Abdulla M
Asian Pac J Cancer Prev 2024 Jul 1;25(7):2499-2507. doi: 10.31557/APJCP.2024.25.7.2499. PMID: 39068585Free PMC Article
Surgically targeted radiation therapy (STaRT) for recurrent brain metastases: Initial clinical experience.
Kutuk T, Tolakanahalli R, Chaswal V, Yarlagadda S, Herrera R, Appel H, La Rosa A, Mishra V, Wieczorek DJJ, McDermott MW, Siomin V, Mehta MP, Odia Y, Gutierrez AN, Kotecha R
Brachytherapy 2023 Nov-Dec;22(6):872-881. Epub 2023 Sep 16 doi: 10.1016/j.brachy.2023.08.002. PMID: 37722990
Twelve-month safety, tolerability and susceptibility to adverse events of prophylactic migraine therapy with erenumab: a retrospective real-world study.
Schenk H, Holle D, Nsaka M, Kleinschnitz C, Glas M, Scheffler A
J Headache Pain 2022 May 11;23(1):55. doi: 10.1186/s10194-022-01426-8. PMID: 35538414Free PMC Article

Clinical prediction guides

Phase I non-randomized clinical trial of allogeneic natural killer cells infusion in acute myeloid leukemia patients.
Ahmadvand M, Barough MS, Barkhordar M, Faridfar A, Ghaderi A, Jalaeikhoo H, Rajaienejad M, Majidzadeh K, Ghavamzadeh A, Sarrami-Forooshani R
BMC Cancer 2023 Nov 10;23(1):1090. doi: 10.1186/s12885-023-11610-x. PMID: 37950209Free PMC Article
Safety, immunogenecity and effectiveness of ChAdOx1 nCoV-19 vaccine during the second wave of pandemic in India: a real-world study.
Chavan P, Dey R, Castelino R, Kamble A, Poladia P, Bagal R, Jadhav M, Shirsat A, Chavan A, Dhumal S, Kumar S, Krishnamurty MN, Bhat V, Bhattacharjee A, Gota V
Drug Metab Pers Ther 2023 Sep 1;38(3):227-236. Epub 2023 Apr 26 doi: 10.1515/dmpt-2022-0150. PMID: 37098129
Effect of Food on the Pharmacokinetics and Safety of a Novel c-Met Inhibitor SCC244: A Randomized Phase I Study in Healthy Subjects.
Wu J, Xu H, Li H, Ma L, Chen J, Yuan F, Sheng L, Liu C, Chen W, Li X
Drug Des Devel Ther 2023;17:761-769. Epub 2023 Mar 10 doi: 10.2147/DDDT.S388846. PMID: 36925997Free PMC Article
A phase 1b randomised, placebo-controlled trial of nabiximols cannabinoid oromucosal spray with temozolomide in patients with recurrent glioblastoma.
Twelves C, Sabel M, Checketts D, Miller S, Tayo B, Jove M, Brazil L, Short SC; GWCA1208 study group
Br J Cancer 2021 Apr;124(8):1379-1387. Epub 2021 Feb 24 doi: 10.1038/s41416-021-01259-3. PMID: 33623076Free PMC Article
Glial injury in neurotoxicity after pediatric CD19-directed chimeric antigen receptor T cell therapy.
Gust J, Finney OC, Li D, Brakke HM, Hicks RM, Futrell RB, Gamble DN, Rawlings-Rhea SD, Khalatbari HK, Ishak GE, Duncan VE, Hevner RF, Jensen MC, Park JR, Gardner RA
Ann Neurol 2019 Jul;86(1):42-54. Epub 2019 May 27 doi: 10.1002/ana.25502. PMID: 31074527Free PMC Article

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