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Impaired pathogen-specific CD8 cytoxicity

MedGen UID:
1619722
Concept ID:
C4531147
Finding
Synonym: Pathogen-specific CD8 cytoxicity defect
 
HPO: HP:0031403

Definition

Impaired response of CD8 T cells to pathogens. CD8 T cells direct the killing of a target cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVImpaired pathogen-specific CD8 cytoxicity

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