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Impairment in personality functioning

MedGen UID:
1613001
Concept ID:
C4531101
Mental or Behavioral Dysfunction
HPO: HP:0031466

Definition

A maladaptive personality trait characterized by moderate or greater impairment in personality (self /interpersonal) functioning. [from HPO]

Professional guidelines

PubMed

Nysaeter TE, Hummelen B, Christensen TB, Eikenaes IU, Selvik SG, Pedersen G, Bender DS, Skodol AE, Paap MCS
J Pers Assess 2023 Jan-Feb;105(1):111-120. Epub 2022 Mar 14 doi: 10.1080/00223891.2022.2039166. PMID: 35285763

Recent clinical studies

Etiology

Doubková N, Heissler R, Barcaj M, Sanders E, Preiss M
Personal Ment Health 2022 Nov;16(4):319-330. Epub 2022 Oct 6 doi: 10.1002/pmh.1569. PMID: 36204774
Reddy S, Hashmi A
Clin Geriatr Med 2020 Aug;36(3):419-429. Epub 2020 Apr 17 doi: 10.1016/j.cger.2020.04.003. PMID: 32586472
Doering S, Blüml V, Parth K, Feichtinger K, Gruber M, Aigner M, Rössler-Schülein H, Freidl M, Wininger A
BMC Psychiatry 2018 Sep 14;18(1):294. doi: 10.1186/s12888-018-1870-0. PMID: 30223818Free PMC Article
Milioni AL, Chaim TM, Cavallet M, de Oliveira NM, Annes M, Dos Santos B, Louzã M, da Silva MA, Miguel CS, Serpa MH, Zanetti MV, Busatto G, Cunha PJ
J Atten Disord 2017 Apr;21(6):455-464. Epub 2016 Jul 28 doi: 10.1177/1087054714554933. PMID: 25359760
Sonuga-Barke E, Bitsakou P, Thompson M
J Am Acad Child Adolesc Psychiatry 2010 Apr;49(4):345-55. doi: 10.1016/j.jaac.2009.12.018. PMID: 20410727

Diagnosis

Reinhard MA, Nenov-Matt T, Padberg F
Curr Psychiatry Rep 2022 Nov;24(11):603-612. Epub 2022 Oct 1 doi: 10.1007/s11920-022-01368-7. PMID: 36181573Free PMC Article
Wagner-Skacel J, Matzer F, Kohlhammer-Dohr A, Dalkner N, Jauk E
Wien Klin Wochenschr 2022 Aug;134(15-16):602-610. Epub 2022 Mar 28 doi: 10.1007/s00508-021-01993-x. PMID: 35344100Free PMC Article
Birkhölzer M, Schmeck K, Goth K
Curr Opin Psychol 2021 Feb;37:98-103. Epub 2020 Sep 22 doi: 10.1016/j.copsyc.2020.09.009. PMID: 33099168
Milioni AL, Chaim TM, Cavallet M, de Oliveira NM, Annes M, Dos Santos B, Louzã M, da Silva MA, Miguel CS, Serpa MH, Zanetti MV, Busatto G, Cunha PJ
J Atten Disord 2017 Apr;21(6):455-464. Epub 2016 Jul 28 doi: 10.1177/1087054714554933. PMID: 25359760
Hülür G, Gerstorf D
Gerontology 2015;61(3):218-22. Epub 2015 Mar 19 doi: 10.1159/000371757. PMID: 25790841

Therapy

Gibson E, Koh CL, Eames S, Bennett S, Scott AM, Hoffmann TC
Cochrane Database Syst Rev 2022 Mar 29;3(3):CD006430. doi: 10.1002/14651858.CD006430.pub3. PMID: 35349186Free PMC Article
Clare L, Kudlicka A, Oyebode JR, Jones RW, Bayer A, Leroi I, Kopelman M, James IA, Culverwell A, Pool J, Brand A, Henderson C, Hoare Z, Knapp M, Morgan-Trimmer S, Burns A, Corbett A, Whitaker R, Woods B
Health Technol Assess 2019 Mar;23(10):1-242. doi: 10.3310/hta23100. PMID: 30879470Free PMC Article
Vuralli D, Ayata C, Bolay H
J Headache Pain 2018 Nov 15;19(1):109. doi: 10.1186/s10194-018-0933-4. PMID: 30442090Free PMC Article
Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C
Cochrane Database Syst Rev 2018 Jul 11;7(7):CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119Free PMC Article
Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D
Exp Gerontol 2018 Jul 15;108:166-173. Epub 2018 Apr 25 doi: 10.1016/j.exger.2018.04.013. PMID: 29704637Free PMC Article

Prognosis

Clougher D, Forte MF, Mezquida G, Sánchez-Torres AM, Serra-Navarro M, Penadés R, Lobo A, Pinto AG, Panadero R, Roldán A, Vieta E, de la Serna E, Trabsa A, Martínez-Aran A, Torrent C, Tortorella A, Menculini G, Ramos-Quiroga JA, Cuesta MJ, Bernardo M, Amoretti S; PEPs group
Eur Neuropsychopharmacol 2024 Aug;85:66-77. Epub 2024 Jul 15 doi: 10.1016/j.euroneuro.2024.05.006. PMID: 39013243
Kerber A, Gewehr E, Zimmermann J, Sachser C, M Fegert J, Knaevelsrud C, Spitzer C
Personal Ment Health 2023 Aug;17(3):246-258. Epub 2023 Feb 5 doi: 10.1002/pmh.1578. PMID: 36740219
Fowler JC, Lamkin J, Allen JG, Madan A, Oldham JM, Petersen NJ, Frueh BC
Psychotherapy (Chic) 2022 Mar;59(1):38-47. Epub 2021 Dec 23 doi: 10.1037/pst0000421. PMID: 34941338
Konstantakopoulos G
Psychiatriki 2019 Jan-Mar;30(1):13-16. doi: 10.22365/jpsych.2019.301.13. PMID: 31115349
Gillie BL, Vasey MW, Thayer JF
Psychol Sci 2014 Feb;25(2):458-65. Epub 2013 Dec 13 doi: 10.1177/0956797613508789. PMID: 24335601

Clinical prediction guides

Nador JD, Zoia M, Pachai MV, Ramon M
Sci Rep 2021 Jun 23;11(1):13184. doi: 10.1038/s41598-021-92549-6. PMID: 34162959Free PMC Article
Konstantakopoulos G
Psychiatriki 2019 Jan-Mar;30(1):13-16. doi: 10.22365/jpsych.2019.301.13. PMID: 31115349
Doering S, Blüml V, Parth K, Feichtinger K, Gruber M, Aigner M, Rössler-Schülein H, Freidl M, Wininger A
BMC Psychiatry 2018 Sep 14;18(1):294. doi: 10.1186/s12888-018-1870-0. PMID: 30223818Free PMC Article
Gillie BL, Vasey MW, Thayer JF
Psychol Sci 2014 Feb;25(2):458-65. Epub 2013 Dec 13 doi: 10.1177/0956797613508789. PMID: 24335601
Sabbagh MA
Brain Cogn 2004 Jun;55(1):209-19. doi: 10.1016/j.bandc.2003.04.002. PMID: 15134854

Recent systematic reviews

Gómez-Soria I, Iguacel I, Aguilar-Latorre A, Peralta-Marrupe P, Latorre E, Zaldívar JNC, Calatayud E
Arch Gerontol Geriatr 2023 Jan;104:104807. Epub 2022 Sep 6 doi: 10.1016/j.archger.2022.104807. PMID: 36116285
Gibson E, Koh CL, Eames S, Bennett S, Scott AM, Hoffmann TC
Cochrane Database Syst Rev 2022 Mar 29;3(3):CD006430. doi: 10.1002/14651858.CD006430.pub3. PMID: 35349186Free PMC Article
Crivelli L, Palmer K, Calandri I, Guekht A, Beghi E, Carroll W, Frontera J, García-Azorín D, Westenberg E, Winkler AS, Mangialasche F, Allegri RF, Kivipelto M
Alzheimers Dement 2022 May;18(5):1047-1066. Epub 2022 Mar 17 doi: 10.1002/alz.12644. PMID: 35297561Free PMC Article
Thieme H, Morkisch N, Mehrholz J, Pohl M, Behrens J, Borgetto B, Dohle C
Cochrane Database Syst Rev 2018 Jul 11;7(7):CD008449. doi: 10.1002/14651858.CD008449.pub3. PMID: 29993119Free PMC Article
Oosterwijk AM, Nieuwenhuis MK, van der Schans CP, Mouton LJ
Physiother Theory Pract 2018 Jul;34(7):505-528. Epub 2018 Jan 29 doi: 10.1080/09593985.2017.1422206. PMID: 29377745

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