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Splenic Burkitt Lymphoma

MedGen UID:
151942
•Concept ID:
C0686546
•
Neoplastic Process
Synonyms: Burkitt lymphoma of spleen; Burkitt tumor of spleen; Burkitt's lymphoma of spleen; Primary Splenic Burkitt's Lymphoma; Splenic Burkitt's Lymphoma
SNOMED CT: Burkitt lymphoma of spleen (188516007); Burkitt's lymphoma of spleen (188516007); Burkitt tumor of spleen (188516007)

Definition

Burkitt lymphoma that involves the spleen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSplenic Burkitt Lymphoma

Professional guidelines

PubMed

Comparison of Myocyte Enhancer Factor 2B Versus Other Germinal Center-associated Antigens in the Differential Diagnosis of B-Cell Non-Hodgkin Lymphomas.
Moore EM, Swerdlow SH, Gibson SE
Am J Surg Pathol 2018 Mar;42(3):342-350. doi: 10.1097/PAS.0000000000001015. PMID: 29309299
Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.
Onaindia A, Medeiros LJ, Patel KP
Mod Pathol 2017 Oct;30(10):1338-1366. Epub 2017 Jun 30 doi: 10.1038/modpathol.2017.58. PMID: 28664939
Differential expression of CD200 in B-cell neoplasms by flow cytometry can assist in diagnosis, subclassification, and bone marrow staging.
Challagundla P, Medeiros LJ, Kanagal-Shamanna R, Miranda RN, Jorgensen JL
Am J Clin Pathol 2014 Dec;142(6):837-44. doi: 10.1309/AJCPBV9ELXC0ECVL. PMID: 25389338

Recent clinical studies

Etiology

Frequency of MYD88 L256P mutation and its correlation with clinico-hematological profile in mature B-cell neoplasm.
Shekhar R, Naseem S, Binota J, Varma N, Malhotra P
Hematol Oncol Stem Cell Ther 2021 Sep;14(3):231-239. Epub 2020 Nov 13 doi: 10.1016/j.hemonc.2020.10.003. PMID: 33217360
Epstein-Barr virus and its association with disease - a review of relevance to general practice.
Fugl A, Andersen CL
BMC Fam Pract 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3. PMID: 31088382Free PMC Article
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Lymphoma--emerging realities in sub-Saharan Africa.
Sissolak G, Juritz J, Sissolak D, Wood L, Jacobs P
Transfus Apher Sci 2010 Apr;42(2):141-50. Epub 2010 Feb 10 doi: 10.1016/j.transci.2010.01.009. PMID: 20149748
The imaging of Burkitt's and Burkitt-like lymphoma.
Johnson KA, Tung K, Mead G, Sweetenham J
Clin Radiol 1998 Nov;53(11):835-41. doi: 10.1016/s0009-9260(98)80196-7. PMID: 9833788

Diagnosis

Epstein-Barr virus and its association with disease - a review of relevance to general practice.
Fugl A, Andersen CL
BMC Fam Pract 2019 May 14;20(1):62. doi: 10.1186/s12875-019-0954-3. PMID: 31088382Free PMC Article
Genetic aberrations of signaling pathways in lymphomagenesis: revelations from next generation sequencing studies.
Rossi D, Ciardullo C, Gaidano G
Semin Cancer Biol 2013 Dec;23(6):422-30. Epub 2013 May 8 doi: 10.1016/j.semcancer.2013.04.002. PMID: 23665546
Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL
Gene 2013 Dec 10;532(1):1-12. Epub 2012 Dec 14 doi: 10.1016/j.gene.2012.12.009. PMID: 23246696
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Composite lymphoma.
Kim H, Hendrickson R, Dorfman RF
Cancer 1977 Sep;40(3):959-76. doi: 10.1002/1097-0142(197709)40:3<959::aid-cncr2820400302>3.0.co;2-3. PMID: 332325

Therapy

An Anti-CD7 Antibody-Drug Conjugate Target Showing Potent Antitumor Activity for T-Lymphoblastic Leukemia (T-ALL).
Wang S, Zhang R, Zhong K, Guo W, Tong A
Biomolecules 2024 Jan 15;14(1) doi: 10.3390/biom14010106. PMID: 38254706Free PMC Article
Burkitt lymphoma associated with human immunodeficiency virus infection and pulmonary tuberculosis: A case report.
Birlutiu V, Birlutiu RM, Zaharie IS, Sandu M
Medicine (Baltimore) 2020 Dec 24;99(52):e23853. doi: 10.1097/MD.0000000000023853. PMID: 33350777Free PMC Article
Cellular backpackers deliver lymphoma drugs.
Cancer Discov 2015 Aug;5(8):786-7. Epub 2015 Jun 25 doi: 10.1158/2159-8290.CD-NB2015-091. PMID: 26112672
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Establishing SCID mouse models of B-cell non-Hodgkin's lymphoma.
Yan JS, Chen XY, Li WP, Yang Y, Song ZL
Ai Zheng 2009 Feb;28(2):181-3. Epub 2009 Feb 23 PMID: 19550134

Prognosis

Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.
Onaindia A, Medeiros LJ, Patel KP
Mod Pathol 2017 Oct;30(10):1338-1366. Epub 2017 Jun 30 doi: 10.1038/modpathol.2017.58. PMID: 28664939
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Lymphoma--emerging realities in sub-Saharan Africa.
Sissolak G, Juritz J, Sissolak D, Wood L, Jacobs P
Transfus Apher Sci 2010 Apr;42(2):141-50. Epub 2010 Feb 10 doi: 10.1016/j.transci.2010.01.009. PMID: 20149748
The imaging of Burkitt's and Burkitt-like lymphoma.
Johnson KA, Tung K, Mead G, Sweetenham J
Clin Radiol 1998 Nov;53(11):835-41. doi: 10.1016/s0009-9260(98)80196-7. PMID: 9833788
Composite lymphoma.
Kim H, Hendrickson R, Dorfman RF
Cancer 1977 Sep;40(3):959-76. doi: 10.1002/1097-0142(197709)40:3<959::aid-cncr2820400302>3.0.co;2-3. PMID: 332325

Clinical prediction guides

Low rate of spleen involvement in sporadic Burkitt lymphoma at staging on PET-CT.
Davidson T, Priel E, Schiby G, Raskin S, Chikman B, Nissan E, Benjamini O, Nissan J, Goshen E, Ben-Haim S, Salomon O, Avigdor A
Abdom Radiol (NY) 2018 Sep;43(9):2369-2374. doi: 10.1007/s00261-017-1454-3. PMID: 29460043
Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.
Onaindia A, Medeiros LJ, Patel KP
Mod Pathol 2017 Oct;30(10):1338-1366. Epub 2017 Jun 30 doi: 10.1038/modpathol.2017.58. PMID: 28664939
Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B-cell lymphoma distinguishes these tumor types from morphologically and phenotypically similar lymphomas.
Kondratiev S, Duraisamy S, Unitt CL, Green MR, Pinkus GS, Shipp MA, Kutok JL, Drapkin RI, Rodig SJ
Am J Surg Pathol 2011 Oct;35(10):1531-9. doi: 10.1097/PAS.0b013e31822bd476. PMID: 21921781Free PMC Article
Lymphoma--emerging realities in sub-Saharan Africa.
Sissolak G, Juritz J, Sissolak D, Wood L, Jacobs P
Transfus Apher Sci 2010 Apr;42(2):141-50. Epub 2010 Feb 10 doi: 10.1016/j.transci.2010.01.009. PMID: 20149748
Hypermutation in human B cells in vivo and in vitro.
Weller S, Faili A, Aoufouchi S, Guéranger Q, Braun M, Reynaud CA, Weill JC
Ann N Y Acad Sci 2003 Apr;987:158-65. doi: 10.1111/j.1749-6632.2003.tb06044.x. PMID: 12727635

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