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Peroneal neuropathy

MedGen UID:
148182
•Concept ID:
C0747533
•
Disease or Syndrome
Synonyms: Fibular Nerve Disease; Fibular Nerve Diseases; Mononeuropathy, Peroneal; Nerve Disease, Fibular; Neuropathy, Peroneal; Peroneal Mononeuropathies; Peroneal Mononeuropathy; Peroneal Nerve Disease; Peroneal Nerve Diseases; Peroneal Neuropathies; Peroneal Neuropathy
 
Monarch Initiative: MONDO:0002910

Definition

Disease involving the common peroneal nerve or its branches, the deep and superficial peroneal nerves. Lesions of the deep peroneal nerve are associated with paralysis of dorsiflexion of the ankle and toes and loss of sensation from the web space between the first and second toe. Lesions of the superficial peroneal nerve result in weakness or paralysis of the peroneal muscles (which evert the foot) and loss of sensation over the dorsal and lateral surface of the leg. Traumatic injury to the common peroneal nerve near the head of the fibula is a relatively common cause of this condition. (From Joynt, Clinical Neurology, 1995, Ch51, p31) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeroneal neuropathy

Professional guidelines

PubMed

The lower extremity nerve injuries - own experience in surgical treatment.
Gosk J, Rutowski R, Rabczyński J
Folia Neuropathol 2005;43(3):148-52. PMID: 16245209
Practice parameter: utility of electrodiagnostic techniques in evaluating patients with suspected peroneal neuropathy: an evidence-based review.
Marciniak C, Armon C, Wilson J, Miller R
Muscle Nerve 2005 Apr;31(4):520-7. doi: 10.1002/mus.20308. PMID: 15768387
Diagnosis and management of common compression and entrapment neuropathies.
Campbell WW
Neurol Clin 1997 Aug;15(3):549-67. doi: 10.1016/s0733-8619(05)70333-9. PMID: 9227952

Recent clinical studies

Etiology

Peroneal nerve decompression.
Corriveau M, Lescher JD, Hanna AS
Neurosurg Focus 2018 Jan;44(VideoSuppl1):V6. doi: 10.3171/2018.1.FocusVid.17575. PMID: 29291292
Common peroneal neuropathy and cancer.
Simon NG, Kiernan MC
Intern Med J 2012 Jul;42(7):837-40. doi: 10.1111/j.1445-5994.2012.02836.x. PMID: 22805690
Common peroneal nerve decompression.
Ramanan M, Chandran KN
ANZ J Surg 2011 Oct;81(10):707-12. doi: 10.1111/j.1445-2197.2010.05607.x. PMID: 22295311
Compression-caused peroneal neuropathy: commentary from a biopsychologist.
Boatright SL
South Med J 2010 Jan;103(1):66-71. doi: 10.1097/SMJ.0b013e3181c65778. PMID: 19996836
Controversial entrapment neuropathies.
Campbell WW, Landau ME
Neurosurg Clin N Am 2008 Oct;19(4):597-608, vi-vii. doi: 10.1016/j.nec.2008.07.001. PMID: 19010284

Diagnosis

Fibular (peroneal) neuropathy.
Benstead TJ
Handb Clin Neurol 2024;201:149-164. doi: 10.1016/B978-0-323-90108-6.00008-9. PMID: 38697737
Lower extremity entrapment neuropathies.
Madani S, Doughty C
Best Pract Res Clin Rheumatol 2020 Jun;34(3):101565. Epub 2020 Jul 31 doi: 10.1016/j.berh.2020.101565. PMID: 32747188
Entrapment Neuropathies of the Lower Extremity.
Bowley MP, Doughty CT
Med Clin North Am 2019 Mar;103(2):371-382. Epub 2018 Dec 3 doi: 10.1016/j.mcna.2018.10.013. PMID: 30704688
Sciatic neuropathy.
Yuen EC, So YT
Neurol Clin 1999 Aug;17(3):617-31, viii. doi: 10.1016/s0733-8619(05)70155-9. PMID: 10393756
Peroneal neuropathy.
Katirji B
Neurol Clin 1999 Aug;17(3):567-91, vii. doi: 10.1016/s0733-8619(05)70153-5. PMID: 10393754

Therapy

Diagnostic accuracy of ultrasound and MR imaging in peroneal neuropathy: A prospective, single-center study.
Oosterbos C, Weerdt O, Lembrechts M, Radwan A, Brys P, Brusselmans M, Bogaerts K, Peeters R, Van Hoylandt A, Hoornaert S, Lemmens R, Theys T
Muscle Nerve 2024 Sep;70(3):360-370. Epub 2024 Jun 27 doi: 10.1002/mus.28187. PMID: 38934723
Peroneal neuropathy and bariatric surgery: untying the knot.
Fares MY, Dimassi Z, Fares J, Musharrafieh U
Int J Neurosci 2020 Apr;130(4):417-423. Epub 2020 Jan 6 doi: 10.1080/00207454.2019.1694926. PMID: 31735096
Peroneal neuropathy following liver transplantation: possible predisposing factors and outcome.
Singhal A, Varma M, Goyal N, Vij V, Wadhawan M, Gupta S
Exp Clin Transplant 2009 Dec;7(4):252-5. PMID: 20353377
Compressive neuropathies complicating normal childbirth: case report and literature review.
Sahai-Srivastava S, Amezcua L
Birth 2007 Jun;34(2):173-5. doi: 10.1111/j.1523-536X.2007.00164.x. PMID: 17542822
Peroneal neuropathy after weight loss.
Cruz-Martinez A, Arpa J, Palau F
J Peripher Nerv Syst 2000 Jun;5(2):101-5. doi: 10.1046/j.1529-8027.2000.00007.x. PMID: 10905469

Prognosis

Electrodiagnostic Assessment of Uncommon Mononeuropathies.
Hayat G, Calvin JS
Neurol Clin 2021 Nov;39(4):957-981. Epub 2021 Sep 3 doi: 10.1016/j.ncl.2021.06.005. PMID: 34602221
Common peroneal nerve decompression.
Ramanan M, Chandran KN
ANZ J Surg 2011 Oct;81(10):707-12. doi: 10.1111/j.1445-2197.2010.05607.x. PMID: 22295311
Foot drop: where, why and what to do?
Stewart JD
Pract Neurol 2008 Jun;8(3):158-69. doi: 10.1136/jnnp.2008.149393. PMID: 18502948
Sciatic neuropathy.
Yuen EC, So YT
Neurol Clin 1999 Aug;17(3):617-31, viii. doi: 10.1016/s0733-8619(05)70155-9. PMID: 10393756
Peroneal neuropathy.
Katirji B
Neurol Clin 1999 Aug;17(3):567-91, vii. doi: 10.1016/s0733-8619(05)70153-5. PMID: 10393754

Clinical prediction guides

Bilateral peroneal nerve palsy due to prolonged squatting in farmers: clinical and electrophysiological outcome.
Yildirim A, Temel M
Neurol Res 2023 Feb;45(2):118-123. Epub 2022 Sep 16 doi: 10.1080/01616412.2022.2124793. PMID: 36111735
Identifying Common Peroneal Neuropathy before Foot Drop.
Lu JC, Dengler J, Poppler LH, Van Handel A, Linkugel A, Jacobson L, Mackinnon SE
Plast Reconstr Surg 2020 Sep;146(3):664-675. doi: 10.1097/PRS.0000000000007096. PMID: 32459730
Peroneal neuropathy after weight loss: a high-resolution ultrasonographic characterization of the common peroneal nerve.
Meylaerts L, Cardinaels E, Vandevenne J, Velghe B, Gelin G, Vanormelingen L, Weyns F
Skeletal Radiol 2011 Dec;40(12):1557-62. Epub 2011 May 3 doi: 10.1007/s00256-011-1177-4. PMID: 21534018
Peroneal neuropathy following liver transplantation: possible predisposing factors and outcome.
Singhal A, Varma M, Goyal N, Vij V, Wadhawan M, Gupta S
Exp Clin Transplant 2009 Dec;7(4):252-5. PMID: 20353377
Foot drop: where, why and what to do?
Stewart JD
Pract Neurol 2008 Jun;8(3):158-69. doi: 10.1136/jnnp.2008.149393. PMID: 18502948

Recent systematic reviews

Analysis of outcome reporting in common peroneal neuropathy studies: a systematic review of the literature.
Muhlestein WE, Wilson TJ
Acta Neurochir (Wien) 2023 Sep;165(9):2597-2604. Epub 2023 Aug 16 doi: 10.1007/s00701-023-05744-x. PMID: 37587319
Editorial. Analysis of outcome reporting in common peroneal neuropathy studies: a systematic review of the literature.
Barone DG, Spinner RJ
Acta Neurochir (Wien) 2023 Sep;165(9):2605-2606. Epub 2023 Aug 12 doi: 10.1007/s00701-023-05747-8. PMID: 37568005
Management and outcomes of proximal tibiofibular joint ganglion cysts: A systematic review.
Huntington LS, Talia A, Devitt BM, Batty L
Knee 2022 Aug;37:60-70. Epub 2022 Jun 10 doi: 10.1016/j.knee.2022.05.009. PMID: 35696835
Nervous system dysfunction in Henoch-Schonlein syndrome: systematic review of the literature.
Garzoni L, Vanoni F, Rizzi M, Simonetti GD, Goeggel Simonetti B, Ramelli GP, Bianchetti MG
Rheumatology (Oxford) 2009 Dec;48(12):1524-9. Epub 2009 Sep 21 doi: 10.1093/rheumatology/kep282. PMID: 19797041

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