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Benign neoplasm of epicardium

MedGen UID:
146342
•Concept ID:
C0685115
•
Neoplastic Process
Synonyms: Benign Epicardial Neoplasm; benign epicardial neoplasm; Benign Epicardial Tumor; benign epicardial tumor; benign epicardial tumour; Benign Neoplasm of Epicardium; benign neoplasm of epicardium; Benign Neoplasm of the Epicardium; benign neoplasm of the epicardium; Benign Tumor of Epicardium; benign tumor of epicardium; Benign Tumor of the Epicardium; benign tumor of the epicardium; benign tumour of epicardium; benign tumour of the epicardium; epicardium benign neoplasm
SNOMED CT: Benign neoplasm of epicardium (92087008)
 
Monarch Initiative: MONDO:0021508

Definition

A neoplasm that arises from the inner layer of pericardium and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of epicardium

Professional guidelines

PubMed

Update on diagnosis and management of neoplastic pericardial disease.
Avondo S, Andreis A, Casula M, Imazio M
Expert Rev Cardiovasc Ther 2020 Sep;18(9):615-623. Epub 2020 Aug 25 doi: 10.1080/14779072.2020.1811087. PMID: 32797759
Management of neoplastic pericardial disease.
Zhang J, Zhang Q, Chen X, Zhang N
Herz 2020 Dec;45(Suppl 1):46-51. Epub 2019 Jul 11 doi: 10.1007/s00059-019-4833-4. PMID: 31297544
2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC)Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS).
Adler Y, Charron P, Imazio M, Badano L, Barón-Esquivias G, Bogaert J, Brucato A, Gueret P, Klingel K, Lionis C, Maisch B, Mayosi B, Pavie A, Ristic AD, Sabaté Tenas M, Seferovic P, Swedberg K, Tomkowski W; ESC Scientific Document Group
Eur Heart J 2015 Nov 7;36(42):2921-2964. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv318. PMID: 26320112Free PMC Article

Recent clinical studies

Etiology

Pericardial Mesotheliomas.
Arrossi AV
Adv Anat Pathol 2023 Jul 1;30(4):253-258. Epub 2023 Apr 27 doi: 10.1097/PAP.0000000000000399. PMID: 37104724
Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Radiation-Associated Pericardial Disease.
Szpakowski N, Desai MY
Curr Cardiol Rep 2019 Jul 27;21(9):97. doi: 10.1007/s11886-019-1192-y. PMID: 31352541
Polyserositis: a diagnostic challenge.
Losada I, González-Moreno J, Roda N, Ventayol L, Borjas Y, Domínguez FJ, Fernández-Baca V, García-Gasalla M, Payeras A
Intern Med J 2018 Aug;48(8):982-987. doi: 10.1111/imj.13966. PMID: 29761620
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550

Diagnosis

Update on diagnosis and management of neoplastic pericardial disease.
Avondo S, Andreis A, Casula M, Imazio M
Expert Rev Cardiovasc Ther 2020 Sep;18(9):615-623. Epub 2020 Aug 25 doi: 10.1080/14779072.2020.1811087. PMID: 32797759
Imaging of Pericardial Disease.
Kligerman S
Radiol Clin North Am 2019 Jan;57(1):179-199. doi: 10.1016/j.rcl.2018.09.001. PMID: 30454812
Congenital Abnormalities of the Pericardium.
Parmar YJ, Shah AB, Poon M, Kronzon I
Cardiol Clin 2017 Nov;35(4):601-614. doi: 10.1016/j.ccl.2017.07.012. PMID: 29025550
Neoplastic Pericardial Disease.
Maleszewski JJ, Anavekar NS
Cardiol Clin 2017 Nov;35(4):589-600. Epub 2017 Sep 6 doi: 10.1016/j.ccl.2017.07.011. PMID: 29025549
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554

Therapy

Pericardial Involvement in Cancer.
Chahine J, Shekhar S, Mahalwar G, Imazio M, Collier P, Klein A
Am J Cardiol 2021 Apr 15;145:151-159. Epub 2021 Jan 15 doi: 10.1016/j.amjcard.2020.12.092. PMID: 33460602
Pericardial Disease Associated with Malignancy.
Schusler R, Meyerson SL
Curr Cardiol Rep 2018 Aug 20;20(10):92. doi: 10.1007/s11886-018-1040-5. PMID: 30128844
Radiation-related heart and vascular disease.
Yusuf SW, Howell RM, Gomez D, Pinnix CC, Iliescu CA, Banchs J
Future Oncol 2015;11(14):2067-76. doi: 10.2217/fon.15.129. PMID: 26198837
Malignant pericardial effusion.
Burazor I, Imazio M, Markel G, Adler Y
Cardiology 2013;124(4):224-32. Epub 2013 Apr 5 doi: 10.1159/000348559. PMID: 23571453
Purulent pericarditis.
Kennedy C, McEvoy S
Ir J Med Sci 2009 Mar;178(1):97-9. Epub 2008 Jan 23 doi: 10.1007/s11845-008-0119-1. PMID: 18214575

Prognosis

Multimodality Imaging for the Assessment of Pericardial Diseases.
Chetrit M, Xu B, Verma BR, Klein AL
Curr Cardiol Rep 2019 Apr 16;21(5):41. doi: 10.1007/s11886-019-1115-y. PMID: 30993456
Pericardial Disease Associated with Malignancy.
Schusler R, Meyerson SL
Curr Cardiol Rep 2018 Aug 20;20(10):92. doi: 10.1007/s11886-018-1040-5. PMID: 30128844
Under Pressure.
DeFilippis EM, Vaidya A, Ramani S, French C, Kirshenbaum JM
N Engl J Med 2017 Mar 30;376(13):e23. doi: 10.1056/NEJMimc1609719. PMID: 28355512
Primary pericardial tumors.
Restrepo CS, Vargas D, Ocazionez D, Martínez-Jiménez S, Betancourt Cuellar SL, Gutierrez FR
Radiographics 2013 Oct;33(6):1613-30. doi: 10.1148/rg.336135512. PMID: 24108554
Purulent pericarditis.
Kennedy C, McEvoy S
Ir J Med Sci 2009 Mar;178(1):97-9. Epub 2008 Jan 23 doi: 10.1007/s11845-008-0119-1. PMID: 18214575

Clinical prediction guides

Clinical Utility of [(18)F]FDG-PET /CT in Pericardial Disease.
Kim MS, Kim EK, Choi JY, Oh JK, Chang SA
Curr Cardiol Rep 2019 Aug 2;21(9):107. doi: 10.1007/s11886-019-1193-x. PMID: 31376028
Polyserositis: a diagnostic challenge.
Losada I, González-Moreno J, Roda N, Ventayol L, Borjas Y, Domínguez FJ, Fernández-Baca V, García-Gasalla M, Payeras A
Intern Med J 2018 Aug;48(8):982-987. doi: 10.1111/imj.13966. PMID: 29761620
Spectrum of physiological and pathological cardiac and pericardial uptake of FDG in oncology PET-CT.
Lobert P, Brown RK, Dvorak RA, Corbett JR, Kazerooni EA, Wong KK
Clin Radiol 2013 Jan;68(1):e59-71. Epub 2012 Nov 22 doi: 10.1016/j.crad.2012.09.007. PMID: 23177651
Multimodality imaging of pericardial diseases.
Yared K, Baggish AL, Picard MH, Hoffmann U, Hung J
JACC Cardiovasc Imaging 2010 Jun;3(6):650-60. doi: 10.1016/j.jcmg.2010.04.009. PMID: 20541720
Malignant mesothelioma.
Kao SC, Reid G, Lee K, Vardy J, Clarke S, van Zandwijk N
Intern Med J 2010 Nov;40(11):742-50. doi: 10.1111/j.1445-5994.2010.02223.x. PMID: 20298508

Recent systematic reviews

Extramedullary disease in multiple myeloma: a systematic literature review.
Bladé J, Beksac M, Caers J, Jurczyszyn A, von Lilienfeld-Toal M, Moreau P, Rasche L, Rosiñol L, Usmani SZ, Zamagni E, Richardson P
Blood Cancer J 2022 Mar 21;12(3):45. doi: 10.1038/s41408-022-00643-3. PMID: 35314675Free PMC Article
Immune checkpoint inhibitor use and tuberculosis: a systematic review of the literature.
Zaemes J, Kim C
Eur J Cancer 2020 Jun;132:168-175. Epub 2020 May 3 doi: 10.1016/j.ejca.2020.03.015. PMID: 32375103
Prenatal management of fetal intrapericardial teratoma: a systematic review.
Nassr AA, Shazly SA, Morris SA, Ayres N, Espinoza J, Erfani H, Olutoye OA, Sexson SK, Olutoye OO, Fraser CD Jr, Belfort MA, Shamshirsaz AA
Prenat Diagn 2017 Sep;37(9):849-863. Epub 2017 Aug 7 doi: 10.1002/pd.5113. PMID: 28695637
Epidemiology of mesothelioma of the pericardium and tunica vaginalis testis.
Mezei G, Chang ET, Mowat FS, Moolgavkar SH
Ann Epidemiol 2017 May;27(5):348-359.e11. Epub 2017 Apr 14 doi: 10.1016/j.annepidem.2017.04.001. PMID: 28527639
Systematic review of percutaneous interventions for malignant pericardial effusion.
Virk SA, Chandrakumar D, Villanueva C, Wolfenden H, Liou K, Cao C
Heart 2015 Oct;101(20):1619-26. Epub 2015 Jul 15 doi: 10.1136/heartjnl-2015-307907. PMID: 26180077

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