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Bowel urgency

MedGen UID:
140873
•Concept ID:
C0426636
•
Finding; Sign or Symptom
Synonyms: Defecation Urgency; Defecation urgency; Faecal urgency; Fecal urgency; Precipitancy of defecation; Urgent desire for stool
SNOMED CT: Defecation urgency (71820002); Fecal urgency (71820002); Precipitancy of defecation (71820002); Urgent desire for stool (71820002)
 
HPO: HP:0012701

Definition

A sudden, irresistible need to have a bowel movement. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBowel urgency

Professional guidelines

PubMed

Mirikizumab: A New Therapeutic Option for the Treatment of Ulcerative Colitis.
Choi D, Sheridan H, Bhat S
Ann Pharmacother 2024 Nov;58(11):1134-1139. Epub 2024 Feb 12 doi: 10.1177/10600280241229742. PMID: 38344998
Defining Comprehensive Disease Control for Use as a Treatment Target for Ulcerative Colitis in Clinical Practice: International Delphi Consensus Recommendations.
Schreiber S, Danese S, Dignass A, Domènech E, Fantini MC, Ferrante M, Halfvarson J, Hart A, Magro F, Lees CW, Leone S, Pierik MJ, Peters M, Field P, Fishpool H, Peyrin-Biroulet L
J Crohns Colitis 2024 Jan 27;18(1):91-105. doi: 10.1093/ecco-jcc/jjad130. PMID: 37586038Free PMC Article
Upadacitinib Therapy Reduces Ulcerative Colitis Symptoms as Early as Day 1 of Induction Treatment.
Loftus EV Jr, Colombel JF, Takeuchi K, Gao X, Panaccione R, Danese S, Dubinsky M, Schreiber S, Ilo D, Finney-Hayward T, Zhou W, Phillips C, Gonzalez YS, Shu L, Yao X, Zhou Q, Vermeire S
Clin Gastroenterol Hepatol 2023 Aug;21(9):2347-2358.e6. Epub 2022 Dec 1 doi: 10.1016/j.cgh.2022.11.029. PMID: 36464141

Recent clinical studies

Etiology

Patient Perspectives of Bowel Urgency and Bowel Urgency-Related Accidents in Ulcerative Colitis and Crohn's Disease.
Jairath V, Hunter Gibble T, Potts Bleakman A, Chatterton K, Medrano P, McLafferty M, Klooster B, Saxena S, Moses R
Inflamm Bowel Dis 2024 Oct 3;30(10):1831-1842. doi: 10.1093/ibd/izae044. PMID: 38513272Free PMC Article
Histologic assessments in ulcerative colitis: the evidence behind a new endpoint in clinical trials.
Pai RK, D'Haens G, Kobayashi T, Sands BE, Travis S, Jairath V, De Hertogh G, Park B, McGinnis K, Redondo I, Lipitz NG, Gibble TH, Magro F
Expert Rev Gastroenterol Hepatol 2024 Jan-Feb;18(1-3):73-87. Epub 2024 Mar 21 doi: 10.1080/17474124.2024.2326838. PMID: 38509826
Supported online self-management versus care as usual for symptoms of fatigue, pain and urgency/incontinence in adults with inflammatory bowel disease (IBD-BOOST): study protocol for a randomised controlled trial.
Norton C, Syred J, Kerry S, Artom M, Sweeney L, Hart A, Czuber-Dochan W, Taylor SJC, Mihaylova B, Roukas C, Aziz Q, Miller L, Pollok R, Saxena S, Stagg I, Terry H, Zenasni Z, Dibley L, Moss-Morris R
Trials 2021 Aug 3;22(1):516. doi: 10.1186/s13063-021-05466-4. PMID: 34344432Free PMC Article
Evaluating the Prevalence of Pelvic Floor Disorders in Women in Nonmetropolitan Communities.
Khan A, Zhang N, Carolan A, Tay K, Wolter C
Female Pelvic Med Reconstr Surg 2021 Feb 1;27(2):e295-e300. doi: 10.1097/SPV.0000000000000908. PMID: 33497070
Low-fat diet after cholecystectomy: Should it be systematically recommended?
Ribas Blasco Y, Pérez Muñante M, Gómez-Fernández L, Jovell-Fernández E, Oms Bernad LM
Cir Esp (Engl Ed) 2020 Jan;98(1):36-42. Epub 2019 Oct 14 doi: 10.1016/j.ciresp.2019.05.009. PMID: 31623819

Diagnosis

Patient Perspectives of Bowel Urgency and Bowel Urgency-Related Accidents in Ulcerative Colitis and Crohn's Disease.
Jairath V, Hunter Gibble T, Potts Bleakman A, Chatterton K, Medrano P, McLafferty M, Klooster B, Saxena S, Moses R
Inflamm Bowel Dis 2024 Oct 3;30(10):1831-1842. doi: 10.1093/ibd/izae044. PMID: 38513272Free PMC Article
Upadacitinib Therapy Reduces Ulcerative Colitis Symptoms as Early as Day 1 of Induction Treatment.
Loftus EV Jr, Colombel JF, Takeuchi K, Gao X, Panaccione R, Danese S, Dubinsky M, Schreiber S, Ilo D, Finney-Hayward T, Zhou W, Phillips C, Gonzalez YS, Shu L, Yao X, Zhou Q, Vermeire S
Clin Gastroenterol Hepatol 2023 Aug;21(9):2347-2358.e6. Epub 2022 Dec 1 doi: 10.1016/j.cgh.2022.11.029. PMID: 36464141
Supported online self-management versus care as usual for symptoms of fatigue, pain and urgency/incontinence in adults with inflammatory bowel disease (IBD-BOOST): study protocol for a randomised controlled trial.
Norton C, Syred J, Kerry S, Artom M, Sweeney L, Hart A, Czuber-Dochan W, Taylor SJC, Mihaylova B, Roukas C, Aziz Q, Miller L, Pollok R, Saxena S, Stagg I, Terry H, Zenasni Z, Dibley L, Moss-Morris R
Trials 2021 Aug 3;22(1):516. doi: 10.1186/s13063-021-05466-4. PMID: 34344432Free PMC Article
Bowel, bladder, and sudomotor symptoms in ALS patients.
Samara VC, Jerant P, Gibson S, Bromberg M
J Neurol Sci 2021 Aug 15;427:117543. Epub 2021 Jun 17 doi: 10.1016/j.jns.2021.117543. PMID: 34182195
Upadacitinib Treatment Improves Symptoms of Bowel Urgency and Abdominal Pain, and Correlates With Quality of Life Improvements in Patients With Moderate to Severe Ulcerative Colitis.
Ghosh S, Sanchez Gonzalez Y, Zhou W, Clark R, Xie W, Louis E, Loftus EV, Panes J, Danese S
J Crohns Colitis 2021 Dec 18;15(12):2022-2030. doi: 10.1093/ecco-jcc/jjab099. PMID: 34107013Free PMC Article

Therapy

Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme.
Danese S, Dignass A, Matsuoka K, Ferrante M, Long M, Redondo I, Moses R, Maier S, Hunter Gibble T, Morris N, Milch C, Abreu MT
J Crohns Colitis 2024 Nov 4;18(11):1845-1856. doi: 10.1093/ecco-jcc/jjae088. PMID: 38869019Free PMC Article
Resolving Histological Inflammation in Ulcerative Colitis With Mirikizumab in the LUCENT Induction and Maintenance Trial Programmes.
Magro F, Pai RK, Kobayashi T, Jairath V, Rieder F, Redondo I, Lissoos T, Morris N, Shan M, Park M, Peyrin-Biroulet L
J Crohns Colitis 2023 Oct 20;17(9):1457-1470. doi: 10.1093/ecco-jcc/jjad050. PMID: 37057827Free PMC Article
Upadacitinib Induction and Maintenance Therapy Improves Abdominal Pain, Bowel Urgency, and Fatigue in Patients With Ulcerative Colitis: A Post Hoc Analysis of Phase 3 Data.
Danese S, Tran J, D'Haens G, Rubin DT, Aoyama N, Zhou W, Ilo D, Yao X, Sanchez Gonzalez Y, Panaccione R
Inflamm Bowel Dis 2023 Nov 2;29(11):1723-1729. doi: 10.1093/ibd/izad016. PMID: 36790041Free PMC Article
Upadacitinib Therapy Reduces Ulcerative Colitis Symptoms as Early as Day 1 of Induction Treatment.
Loftus EV Jr, Colombel JF, Takeuchi K, Gao X, Panaccione R, Danese S, Dubinsky M, Schreiber S, Ilo D, Finney-Hayward T, Zhou W, Phillips C, Gonzalez YS, Shu L, Yao X, Zhou Q, Vermeire S
Clin Gastroenterol Hepatol 2023 Aug;21(9):2347-2358.e6. Epub 2022 Dec 1 doi: 10.1016/j.cgh.2022.11.029. PMID: 36464141
Low-fat diet after cholecystectomy: Should it be systematically recommended?
Ribas Blasco Y, Pérez Muñante M, Gómez-Fernández L, Jovell-Fernández E, Oms Bernad LM
Cir Esp (Engl Ed) 2020 Jan;98(1):36-42. Epub 2019 Oct 14 doi: 10.1016/j.ciresp.2019.05.009. PMID: 31623819

Prognosis

Early and Sustained Symptom Control with Mirikizumab in Patients with Ulcerative Colitis in the Phase 3 LUCENT Programme.
Danese S, Dignass A, Matsuoka K, Ferrante M, Long M, Redondo I, Moses R, Maier S, Hunter Gibble T, Morris N, Milch C, Abreu MT
J Crohns Colitis 2024 Nov 4;18(11):1845-1856. doi: 10.1093/ecco-jcc/jjae088. PMID: 38869019Free PMC Article
Histologic assessments in ulcerative colitis: the evidence behind a new endpoint in clinical trials.
Pai RK, D'Haens G, Kobayashi T, Sands BE, Travis S, Jairath V, De Hertogh G, Park B, McGinnis K, Redondo I, Lipitz NG, Gibble TH, Magro F
Expert Rev Gastroenterol Hepatol 2024 Jan-Feb;18(1-3):73-87. Epub 2024 Mar 21 doi: 10.1080/17474124.2024.2326838. PMID: 38509826
Resolving Histological Inflammation in Ulcerative Colitis With Mirikizumab in the LUCENT Induction and Maintenance Trial Programmes.
Magro F, Pai RK, Kobayashi T, Jairath V, Rieder F, Redondo I, Lissoos T, Morris N, Shan M, Park M, Peyrin-Biroulet L
J Crohns Colitis 2023 Oct 20;17(9):1457-1470. doi: 10.1093/ecco-jcc/jjad050. PMID: 37057827Free PMC Article
Proctitis following stereotactic body radiation therapy for prostate cancer.
Joh DY, Chen LN, Porter G, Bhagat A, Sood S, Kim JS, Moures R, Yung T, Lei S, Collins BT, Ju AW, Suy S, Carroll J, Lynch JH, Dritschilo A, Collins SP
Radiat Oncol 2014 Dec 12;9:277. doi: 10.1186/s13014-014-0277-4. PMID: 25497602Free PMC Article
Systematic review: comparative effectiveness and harms of treatments for clinically localized prostate cancer.
Wilt TJ, MacDonald R, Rutks I, Shamliyan TA, Taylor BC, Kane RL
Ann Intern Med 2008 Mar 18;148(6):435-48. Epub 2008 Feb 4 doi: 10.7326/0003-4819-148-6-200803180-00209. PMID: 18252677

Clinical prediction guides

Resolving Histological Inflammation in Ulcerative Colitis With Mirikizumab in the LUCENT Induction and Maintenance Trial Programmes.
Magro F, Pai RK, Kobayashi T, Jairath V, Rieder F, Redondo I, Lissoos T, Morris N, Shan M, Park M, Peyrin-Biroulet L
J Crohns Colitis 2023 Oct 20;17(9):1457-1470. doi: 10.1093/ecco-jcc/jjad050. PMID: 37057827Free PMC Article
Upadacitinib Induction and Maintenance Therapy Improves Abdominal Pain, Bowel Urgency, and Fatigue in Patients With Ulcerative Colitis: A Post Hoc Analysis of Phase 3 Data.
Danese S, Tran J, D'Haens G, Rubin DT, Aoyama N, Zhou W, Ilo D, Yao X, Sanchez Gonzalez Y, Panaccione R
Inflamm Bowel Dis 2023 Nov 2;29(11):1723-1729. doi: 10.1093/ibd/izad016. PMID: 36790041Free PMC Article
Upadacitinib Therapy Reduces Ulcerative Colitis Symptoms as Early as Day 1 of Induction Treatment.
Loftus EV Jr, Colombel JF, Takeuchi K, Gao X, Panaccione R, Danese S, Dubinsky M, Schreiber S, Ilo D, Finney-Hayward T, Zhou W, Phillips C, Gonzalez YS, Shu L, Yao X, Zhou Q, Vermeire S
Clin Gastroenterol Hepatol 2023 Aug;21(9):2347-2358.e6. Epub 2022 Dec 1 doi: 10.1016/j.cgh.2022.11.029. PMID: 36464141
Upadacitinib Treatment Improves Symptoms of Bowel Urgency and Abdominal Pain, and Correlates With Quality of Life Improvements in Patients With Moderate to Severe Ulcerative Colitis.
Ghosh S, Sanchez Gonzalez Y, Zhou W, Clark R, Xie W, Louis E, Loftus EV, Panes J, Danese S
J Crohns Colitis 2021 Dec 18;15(12):2022-2030. doi: 10.1093/ecco-jcc/jjab099. PMID: 34107013Free PMC Article
Low-fat diet after cholecystectomy: Should it be systematically recommended?
Ribas Blasco Y, Pérez Muñante M, Gómez-Fernández L, Jovell-Fernández E, Oms Bernad LM
Cir Esp (Engl Ed) 2020 Jan;98(1):36-42. Epub 2019 Oct 14 doi: 10.1016/j.ciresp.2019.05.009. PMID: 31623819

Recent systematic reviews

Systematic Review of Radiation Therapy Toxicity Reporting in Randomized Controlled Trials of Rectal Cancer: A Comparison of Patient-Reported Outcomes and Clinician Toxicity Reporting.
Gilbert A, Ziegler L, Martland M, Davidson S, Efficace F, Sebag-Montefiore D, Velikova G
Int J Radiat Oncol Biol Phys 2015 Jul 1;92(3):555-67. doi: 10.1016/j.ijrobp.2015.02.021. PMID: 26068490
Systematic review: comparative effectiveness and harms of treatments for clinically localized prostate cancer.
Wilt TJ, MacDonald R, Rutks I, Shamliyan TA, Taylor BC, Kane RL
Ann Intern Med 2008 Mar 18;148(6):435-48. Epub 2008 Feb 4 doi: 10.7326/0003-4819-148-6-200803180-00209. PMID: 18252677

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