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Abnormal larynx morphology

MedGen UID:
1374288
•Concept ID:
C4476768
•
Anatomical Abnormality
HPO: HP:0025423

Definition

Any anomaly of the structure of the larynx. [from HPO]

Professional guidelines

PubMed

The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Diagnosis and Management of Laryngotracheoesophageal Cleft.
Sobol SE
Curr Probl Pediatr Adolesc Health Care 2018 Mar;48(3):82-84. doi: 10.1016/j.cppeds.2018.01.007. PMID: 29571545
Laryngeal cleft: evaluation and management.
Johnston DR, Watters K, Ferrari LR, Rahbar R
Int J Pediatr Otorhinolaryngol 2014 Jun;78(6):905-11. Epub 2014 Mar 27 doi: 10.1016/j.ijporl.2014.03.015. PMID: 24735606

Recent clinical studies

Etiology

Histopathology of laryngomalacia.
Gan RWC, Moustafa A, Turner K, Knight L
Acta Otolaryngol 2021 Jan;141(1):85-88. Epub 2020 Oct 14 doi: 10.1080/00016489.2020.1821246. PMID: 33393421
Airway Anomalies.
Landry AM, Rutter MJ
Clin Perinatol 2018 Dec;45(4):597-607. Epub 2018 Sep 11 doi: 10.1016/j.clp.2018.07.002. PMID: 30396407
Pediatric airway surgery.
Maeda K
Pediatr Surg Int 2017 Apr;33(4):435-443. Epub 2017 Jan 28 doi: 10.1007/s00383-016-4050-7. PMID: 28132084
Congenital laryngeal anomalies.
Rutter MJ
Braz J Otorhinolaryngol 2014 Nov-Dec;80(6):533-9. Epub 2014 Aug 21 doi: 10.1016/j.bjorl.2014.08.001. PMID: 25457074Free PMC Article
Mast cell sarcoma: clinical management.
Weiler CR, Butterfield J
Immunol Allergy Clin North Am 2014 May;34(2):423-32. Epub 2014 Mar 13 doi: 10.1016/j.iac.2014.01.004. PMID: 24745684

Diagnosis

Airway Anomalies.
Landry AM, Rutter MJ
Clin Perinatol 2018 Dec;45(4):597-607. Epub 2018 Sep 11 doi: 10.1016/j.clp.2018.07.002. PMID: 30396407
Diagnosis and Management of Laryngotracheoesophageal Cleft.
Sobol SE
Curr Probl Pediatr Adolesc Health Care 2018 Mar;48(3):82-84. doi: 10.1016/j.cppeds.2018.01.007. PMID: 29571545
Congenital laryngeal anomalies.
Rutter MJ
Braz J Otorhinolaryngol 2014 Nov-Dec;80(6):533-9. Epub 2014 Aug 21 doi: 10.1016/j.bjorl.2014.08.001. PMID: 25457074Free PMC Article
Laryngeal cleft.
Watters K, Ferrari L, Rahbar R
Adv Otorhinolaryngol 2012;73:95-100. Epub 2012 Mar 29 doi: 10.1159/000334452. PMID: 22472237
Laryngo-tracheo-oesophageal clefts.
Leboulanger N, Garabédian EN
Orphanet J Rare Dis 2011 Dec 7;6:81. doi: 10.1186/1750-1172-6-81. PMID: 22151899Free PMC Article

Therapy

Neonatal Lateral Epiglottic Defects.
Peterson JD, Goyal V, Puricelli MD, Thatcher A, Smith RJ
Ann Otol Rhinol Laryngol 2021 Mar;130(3):311-313. Epub 2020 Aug 8 doi: 10.1177/0003489420948546. PMID: 32772542
Rigid airway.
Itagane M, Yano H, Kishaba T, Kinjo M
Cleve Clin J Med 2020 Jun;87(6):334-336. doi: 10.3949/ccjm.87a.19129. PMID: 32487551
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Periman LM, Perez VL, Saban DR, Lin MC, Neri P
J Ocul Pharmacol Ther 2020 Apr;36(3):137-146. Epub 2020 Mar 12 doi: 10.1089/jop.2019.0060. PMID: 32175799Free PMC Article
Mast cell sarcoma: clinical management.
Weiler CR, Butterfield J
Immunol Allergy Clin North Am 2014 May;34(2):423-32. Epub 2014 Mar 13 doi: 10.1016/j.iac.2014.01.004. PMID: 24745684
Endogenous ochronosis.
Turgay E, Canat D, Gurel MS, Yuksel T, Baran MF, Demirkesen C
Clin Exp Dermatol 2009 Dec;34(8):e865-8. doi: 10.1111/j.1365-2230.2009.03618.x. PMID: 20055850

Prognosis

Airway Anomalies.
Landry AM, Rutter MJ
Clin Perinatol 2018 Dec;45(4):597-607. Epub 2018 Sep 11 doi: 10.1016/j.clp.2018.07.002. PMID: 30396407
Diagnosis and Management of Laryngotracheoesophageal Cleft.
Sobol SE
Curr Probl Pediatr Adolesc Health Care 2018 Mar;48(3):82-84. doi: 10.1016/j.cppeds.2018.01.007. PMID: 29571545
Pediatric airway surgery.
Maeda K
Pediatr Surg Int 2017 Apr;33(4):435-443. Epub 2017 Jan 28 doi: 10.1007/s00383-016-4050-7. PMID: 28132084
Laryngeal cleft: evaluation and management.
Johnston DR, Watters K, Ferrari LR, Rahbar R
Int J Pediatr Otorhinolaryngol 2014 Jun;78(6):905-11. Epub 2014 Mar 27 doi: 10.1016/j.ijporl.2014.03.015. PMID: 24735606
Laryngo-tracheo-oesophageal clefts.
Leboulanger N, Garabédian EN
Orphanet J Rare Dis 2011 Dec 7;6:81. doi: 10.1186/1750-1172-6-81. PMID: 22151899Free PMC Article

Clinical prediction guides

Histology of Barrett's Metaplasia: Do Goblet Cells Matter?
Odze R
Dig Dis Sci 2018 Aug;63(8):2042-2051. doi: 10.1007/s10620-018-5151-z. PMID: 29998421
Mucins, Mucus, and Goblet Cells.
Ma J, Rubin BK, Voynow JA
Chest 2018 Jul;154(1):169-176. Epub 2017 Nov 21 doi: 10.1016/j.chest.2017.11.008. PMID: 29170036
Sella turcica morphology and the pituitary gland-a new contribution to craniofacial diagnostics based on histology and neuroradiology.
Kjær I
Eur J Orthod 2015 Feb;37(1):28-36. Epub 2012 Nov 16 doi: 10.1093/ejo/cjs091. PMID: 23159420
Clinical and pathological features of pachyonychia congenita.
Leachman SA, Kaspar RL, Fleckman P, Florell SR, Smith FJ, McLean WH, Lunny DP, Milstone LM, van Steensel MA, Munro CS, O'Toole EA, Celebi JT, Kansky A, Lane EB
J Investig Dermatol Symp Proc 2005 Oct;10(1):3-17. doi: 10.1111/j.1087-0024.2005.10202.x. PMID: 16250204
Ankyloglossia with deviation of the epiglottis and larynx.
Mukai S, Mukai C, Asaoka K
Ann Otol Rhinol Laryngol Suppl 1991 May;153:3-20. doi: 10.1177/00034894911000s501. PMID: 2024905

Recent systematic reviews

Surgical treatment of laryngeal amyloidosis: a systematic review.
Galluzzi F, Garavello W
Eur Arch Otorhinolaryngol 2023 Jul;280(7):3065-3074. Epub 2023 Feb 15 doi: 10.1007/s00405-023-07881-6. PMID: 36790723
Management of Type 1 Laryngeal Clefts: A Systematic Review and Meta-analysis.
Timashpolsky A, Schild SD, Ballard DP, Leventer SP, Rosenfeld RM, Plum AW
Otolaryngol Head Neck Surg 2021 Mar;164(3):489-500. Epub 2020 Aug 18 doi: 10.1177/0194599820947742. PMID: 32807006
Presentation and management of type 1 laryngeal clefts: A systematic review and meta-analysis.
Reddy P, Byun YJ, Downs J, Nguyen SA, White DR
Int J Pediatr Otorhinolaryngol 2020 Nov;138:110370. Epub 2020 Sep 9 doi: 10.1016/j.ijporl.2020.110370. PMID: 33152963
Laryngomalacia: is there an evidence base for management?
McCaffer C, Blackmore K, Flood LM
J Laryngol Otol 2017 Nov;131(11):946-954. Epub 2017 Oct 25 doi: 10.1017/S0022215117002092. PMID: 29067893
The groningen laryngomalacia classification system--based on systematic review and dynamic airway changes.
van der Heijden M, Dikkers FG, Halmos GB
Pediatr Pulmonol 2015 Dec;50(12):1368-73. Epub 2015 Mar 30 doi: 10.1002/ppul.23186. PMID: 25825153

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