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Abnormal nasal septum morphology

MedGen UID:
1374137
•Concept ID:
C4316811
•
Anatomical Abnormality
Synonyms: Abnormality of septum of nose; Abnormality of the nasal septum; Anomaly of nasal septum; Anomaly of septum of nose
 
HPO: HP:0000419

Definition

An abnormality of the nasal septum. [from HPO]

Conditions with this feature

Carey-Fineman-Ziter syndrome 2
MedGen UID:
1800921
•Concept ID:
C5677012
•
Disease or Syndrome
Carey-Fineman-Ziter syndrome-2 (CFZS2) is an autosomal recessive disorder characterized by weakness of the facial musculature, hypomimic facies, increased overbite, micrognathia, and facial dysmorphism. Other features may include failure to thrive, axial hypotonia, and progressive scoliosis (Ramirez-Martinez et al., 2022). For a discussion of genetic heterogeneity of Carey-Fineman-Ziter syndrome, see CFZS1 (254940).
See: Condition Record
Carey-Fineman-Ziter syndrome 2

Professional guidelines

PubMed

Management of Pediatric Nasal Surgery (Rhinoplasty).
Johnson MD
Facial Plast Surg Clin North Am 2017 May;25(2):211-221. Epub 2017 Feb 21 doi: 10.1016/j.fsc.2016.12.006. PMID: 28340652
Differential diagnosis of persistent nonallergic rhinitis and rhinosinusitis syndromes.
Staevska MT, Baraniuk JN
Clin Allergy Immunol 2007;19:35-53. PMID: 17153006
The true hanging columella: simplified diagnosis and treatment using a modified direct approach.
Matarasso A, Greer SE, Longaker MT
Plast Reconstr Surg 2000 Aug;106(2):469-74. doi: 10.1097/00006534-200008000-00038. PMID: 10946947

Recent clinical studies

Etiology

Bony Fixation of the Nasal Framework.
Haack S, Hacker S, Mann S, Gubisch W
Facial Plast Surg 2019 Feb;35(1):23-30. Epub 2019 Feb 13 doi: 10.1055/s-0039-1677767. PMID: 30759458
Accessory Nostril: A Rare Congenital Nasal Anomaly.
Gulasi S, Turhan AH, Celik Y, Atici A, Vayisoglu Y, Ünal M
J Craniofac Surg 2015 Oct;26(7):e602-3. doi: 10.1097/SCS.0000000000002048. PMID: 26468836
Cerebrospinal fluid leaks following septoplasty.
Venkatesan NN, Mattox DE, Del Gaudio JM
Ear Nose Throat J 2014 Dec;93(12):E43-6. doi: 10.1177/014556131409301204. PMID: 25531856
Current approaches to septal saddle nose reconstruction using autografts.
Young K, Rowe-Jones J
Curr Opin Otolaryngol Head Neck Surg 2011 Aug;19(4):276-82. doi: 10.1097/MOO.0b013e32834896ce. PMID: 21659875
Calibrated nasal tip: review of 100 cases.
de la Fuente A, Martin del Yerro JL
Aesthetic Plast Surg 1994 Fall;18(4):357-61. doi: 10.1007/BF00451340. PMID: 7817883

Diagnosis

Olfactory cleft dilatation.
Jankowski R, Nguyen DT, Gallet P, Rumeau C
Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec;135(6):437-441. Epub 2018 Jun 20 doi: 10.1016/j.anorl.2018.05.008. PMID: 29934261
Septoplasty pearls.
Dobratz EJ, Park SS
Otolaryngol Clin North Am 2009 Jun;42(3):527-37. doi: 10.1016/j.otc.2009.03.003. PMID: 19486747
Open septoplasty: indications and treatment.
Chaaban M, Shah AR
Otolaryngol Clin North Am 2009 Jun;42(3):513-9. doi: 10.1016/j.otc.2009.03.012. PMID: 19486745
Endoscopic septoplasty.
Dolan RW
Facial Plast Surg 2004 Aug;20(3):217-21. doi: 10.1055/s-2004-861777. PMID: 15643594
Acute nasal sinusitis.
Ryan RE Sr, Ryan RE Jr
Postgrad Med 1974 Sep;56(3):159-63. doi: 10.1080/00325481.1974.11713851. PMID: 4850417

Therapy

Rhinoseptoplasty in children.
Maniglia CP, Maniglia JV
Braz J Otorhinolaryngol 2017 Jul-Aug;83(4):416-419. Epub 2016 May 31 doi: 10.1016/j.bjorl.2016.04.019. PMID: 27339699Free PMC Article
Extracorporeal Septoplasty: External and Endonasal Techniques.
Wu PS, Hamilton GS 3rd
Facial Plast Surg 2016 Feb;32(1):22-8. Epub 2016 Feb 10 doi: 10.1055/s-0035-1570123. PMID: 26862960
Asymmetric nasal tip.
Stephan S, Wang TD
Facial Plast Surg 2012 Apr;28(2):177-86. Epub 2012 May 6 doi: 10.1055/s-0032-1309297. PMID: 22562567
Prenatal exposure to phenytoin, facial development, and a possible role for vitamin K.
Howe AM, Lipson AH, Sheffield LJ, Haan EA, Halliday JL, Jenson F, David DJ, Webster WS
Am J Med Genet 1995 Sep 11;58(3):238-44. doi: 10.1002/ajmg.1320580309. PMID: 8533825
Calibrated nasal tip: review of 100 cases.
de la Fuente A, Martin del Yerro JL
Aesthetic Plast Surg 1994 Fall;18(4):357-61. doi: 10.1007/BF00451340. PMID: 7817883

Prognosis

Bony Fixation of the Nasal Framework.
Haack S, Hacker S, Mann S, Gubisch W
Facial Plast Surg 2019 Feb;35(1):23-30. Epub 2019 Feb 13 doi: 10.1055/s-0039-1677767. PMID: 30759458
Accessory Nostril: A Rare Congenital Nasal Anomaly.
Gulasi S, Turhan AH, Celik Y, Atici A, Vayisoglu Y, Ünal M
J Craniofac Surg 2015 Oct;26(7):e602-3. doi: 10.1097/SCS.0000000000002048. PMID: 26468836
Current approaches to septal saddle nose reconstruction using autografts.
Young K, Rowe-Jones J
Curr Opin Otolaryngol Head Neck Surg 2011 Aug;19(4):276-82. doi: 10.1097/MOO.0b013e32834896ce. PMID: 21659875
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Calibrated nasal tip: review of 100 cases.
de la Fuente A, Martin del Yerro JL
Aesthetic Plast Surg 1994 Fall;18(4):357-61. doi: 10.1007/BF00451340. PMID: 7817883

Clinical prediction guides

Review and update on extracorporeal septoplasty.
McGrath M, Bell E, Locketz GD, Becker DG
Curr Opin Otolaryngol Head Neck Surg 2019 Feb;27(1):1-6. doi: 10.1097/MOO.0000000000000509. PMID: 30507685
Accessory Nostril: A Rare Congenital Nasal Anomaly.
Gulasi S, Turhan AH, Celik Y, Atici A, Vayisoglu Y, Ünal M
J Craniofac Surg 2015 Oct;26(7):e602-3. doi: 10.1097/SCS.0000000000002048. PMID: 26468836
Pediatric septorhinoplasty.
Funamura JL, Sykes JM
Facial Plast Surg Clin North Am 2014 Nov;22(4):503-8. Epub 2014 Nov 8 doi: 10.1016/j.fsc.2014.07.005. PMID: 25444724
Nasal septal deformities in chronic rhinosinusitis patients: clinical and radiological aspects.
Poje G, Zinreich JS, Skitarelić N, Đurić Vuković K, Passàli GC, Passàli D, Mladina R
Acta Otorhinolaryngol Ital 2014 Apr;34(2):117-22. PMID: 24843222Free PMC Article
Cartilaginous incisions in septoplasty.
Min YG, Chung JW
ORL J Otorhinolaryngol Relat Spec 1996 Jan-Feb;58(1):51-4. doi: 10.1159/000276796. PMID: 8718540

Recent systematic reviews

"Primary Correction of the Cleft Nasal Septum: A Systematic Review".
Bins GP, Dourado J, Tang J, Kogan S, Runyan CM
Cleft Palate Craniofac J 2024 Mar;61(3):373-382. Epub 2022 Sep 18 doi: 10.1177/10556656221127539. PMID: 36120835
Anatomical variations and abnormalities of the maxillary region and clinical implications: A systematic review and metaanalysis.
Valenzuela-Fuenzalida JJ, Baez-Flores B, Sepúlveda RÁ, Medina CM, Pérez R, López E, Sanchis J, Orellana Donoso M, Silva JL, Rodriguez MC, Iwanaga J
Medicine (Baltimore) 2023 Sep 22;102(38):e34510. doi: 10.1097/MD.0000000000034510. PMID: 37747000Free PMC Article
Long-term patient-related outcome measures of septoplasty: a systematic review.
Tsang CLN, Nguyen T, Sivesind T, Cervin A
Eur Arch Otorhinolaryngol 2018 May;275(5):1039-1048. Epub 2018 Jan 13 doi: 10.1007/s00405-018-4874-y. PMID: 29332171
Effect of non-surgical maxillary expansion on the nasal septum deviation: a systematic review.
Aziz T, Ansari K, Lagravere MO, Major MP, Flores-Mir C
Prog Orthod 2015;16:15. Epub 2015 Jun 4 doi: 10.1186/s40510-015-0084-y. PMID: 26061988Free PMC Article
Hard palate-repair technique and facial growth in patients with cleft lip and palate: a systematic review.
Lee YH, Liao YF
Br J Oral Maxillofac Surg 2013 Dec;51(8):851-7. Epub 2013 Sep 14 doi: 10.1016/j.bjoms.2013.08.012. PMID: 24045106

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