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Salivary Gland High Grade Carcinoma

MedGen UID:: 124649
•Concept ID:: C0279743
•: Neoplastic Process

Synonyms:

High Grade Salivary Gland Carcinoma; High-Grade Carcinoma of Salivary Gland; High-Grade Carcinoma of the Salivary Gland; Salivary Gland High-Grade Carcinoma

Definition

A usually aggressive salivary gland carcinoma with high-grade histopathologic features. It includes the salivary duct carcinoma, salivary gland oncocytic carcinoma, and high grade salivary gland mucoepidermoid carcinoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSalivary Gland High Grade Carcinoma

Disease
- Neoplasm
  - Epithelial neoplasm
    - Carcinoma
      - Head and neck carcinoma
        Salivary gland carcinoma
        Salivary Gland High Grade Carcinoma
        Salivary duct carcinoma
        Recurrent Salivary Duct Carcinoma
        Salivary Gland High Grade Mucoepidermoid Carcinoma
        Salivary Gland Oncocytic Adenocarcinoma

Professional guidelines

PubMed

Pre-treatment metabolic tumor volume predicts tumor metastasis and progression in high-grade salivary gland carcinoma.

Almuhaimid TM, Lim WS, Roh JL, Oh JS, Kim JS, Kim SJ, Choi SH, Nam SY, Kim SY
J Cancer Res Clin Oncol 2018 Dec;144(12):2485-2493. Epub 2018 Oct 6 doi: 10.1007/s00432-018-2760-z. PMID: 30293119

See all (1)

Recent clinical studies

Etiology

Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach.

Jung CK, Bychkov A, Kakudo K
Endocrinol Metab (Seoul) 2022 Oct;37(5):703-718. Epub 2022 Oct 4 doi: 10.3803/EnM.2022.1553. PMID: 36193717 Free PMC Article

Overview of the 2022 WHO Classification of Thyroid Neoplasms.

Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part B: treatment and prognosis.

Cantù G
Acta Otorhinolaryngol Ital 2021 Aug;41(4):296-307. doi: 10.14639/0392-100X-N1729. PMID: 34533533 Free PMC Article

Major and minor salivary gland tumours.

Gatta G, Guzzo M, Locati LD, McGurk M, Prott FJ
Crit Rev Oncol Hematol 2020 Aug;152:102959. Epub 2020 May 18 doi: 10.1016/j.critrevonc.2020.102959. PMID: 32485526

Salivary duct carcinoma.

D'heygere E, Meulemans J, Vander Poorten V
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):142-151. doi: 10.1097/MOO.0000000000000436. PMID: 29373327

See all (442)

Diagnosis

Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach.

Jung CK, Bychkov A, Kakudo K
Endocrinol Metab (Seoul) 2022 Oct;37(5):703-718. Epub 2022 Oct 4 doi: 10.3803/EnM.2022.1553. PMID: 36193717 Free PMC Article

Overview of the 2022 WHO Classification of Thyroid Neoplasms.

Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment.

Nakaguro M, Tada Y, Faquin WC, Sadow PM, Wirth LJ, Nagao T
Cancer Cytopathol 2020 Oct;128(10):693-703. Epub 2020 May 18 doi: 10.1002/cncy.22288. PMID: 32421944 Free PMC Article

Mucoepidermoid carcinoma.

Devaraju R, Gantala R, Aitha H, Gotoor SG
BMJ Case Rep 2014 Aug 1;2014:bcr-2013-202776. doi: 10.1136/bcr-2013-202776. PMID: 25085946 Free PMC Article

CT and MR imaging findings of palatal tumors.

Kato H, Kanematsu M, Makita H, Kato K, Hatakeyama D, Shibata T, Mizuta K, Aoki M
Eur J Radiol 2014 Mar;83(3):e137-46. Epub 2013 Dec 12 doi: 10.1016/j.ejrad.2013.11.028. PMID: 24377674

See all (516)

Therapy

Neutron Therapy for High-Grade Salivary Carcinomas in the Adjuvant and Primary Treatment Setting.

Cash H, Harbison RA, Futran N, Parvathaneni U, Laramore GE, Liao J, Cannon R, Rodriguez C, Houlton JJ
Laryngoscope 2021 Mar;131(3):541-547. Epub 2020 Jun 30 doi: 10.1002/lary.28830. PMID: 32603506

Intermediate and long-term adverse effects of radioiodine therapy for differentiated thyroid carcinoma--a systematic review.

Clement SC, Peeters RP, Ronckers CM, Links TP, van den Heuvel-Eibrink MM, Nieveen van Dijkum EJ, van Rijn RR, van der Pal HJ, Neggers SJ, Kremer LC, van Eck-Smit BL, van Santen HM
Cancer Treat Rev 2015 Dec;41(10):925-34. Epub 2015 Sep 10 doi: 10.1016/j.ctrv.2015.09.001. PMID: 26421813

Management of salivary gland tumors.

Andry G, Hamoir M, Locati LD, Licitra L, Langendijk JA
Expert Rev Anticancer Ther 2012 Sep;12(9):1161-8. doi: 10.1586/era.12.92. PMID: 23098116

Tracheobronchial gland tumors.

Gaissert HA, Mark EJ
Cancer Control 2006 Oct;13(4):286-94. doi: 10.1177/107327480601300406. PMID: 17075566

Systemic therapy in the palliative management of advanced salivary gland cancers.

Laurie SA, Licitra L
J Clin Oncol 2006 Jun 10;24(17):2673-8. doi: 10.1200/JCO.2005.05.3025. PMID: 16763282

See all (87)

Prognosis

Overview of the 2022 WHO Classification of Thyroid Neoplasms.

Adenoid cystic carcinoma. An indolent but aggressive tumour. Part B: treatment and prognosis.

Cantù G
Acta Otorhinolaryngol Ital 2021 Aug;41(4):296-307. doi: 10.14639/0392-100X-N1729. PMID: 34533533 Free PMC Article

Major and minor salivary gland tumours.

Gatta G, Guzzo M, Locati LD, McGurk M, Prott FJ
Crit Rev Oncol Hematol 2020 Aug;152:102959. Epub 2020 May 18 doi: 10.1016/j.critrevonc.2020.102959. PMID: 32485526

Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment.

Nakaguro M, Tada Y, Faquin WC, Sadow PM, Wirth LJ, Nagao T
Cancer Cytopathol 2020 Oct;128(10):693-703. Epub 2020 May 18 doi: 10.1002/cncy.22288. PMID: 32421944 Free PMC Article

Salivary duct carcinoma.

D'heygere E, Meulemans J, Vander Poorten V
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):142-151. doi: 10.1097/MOO.0000000000000436. PMID: 29373327

See all (547)

Clinical prediction guides

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.

Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977 Free PMC Article

Salivary duct carcinoma.

D'heygere E, Meulemans J, Vander Poorten V
Curr Opin Otolaryngol Head Neck Surg 2018 Apr;26(2):142-151. doi: 10.1097/MOO.0000000000000436. PMID: 29373327

Salivary Duct Carcinoma: An Update on Morphologic Mimics and Diagnostic Use of Androgen Receptor Immunohistochemistry.

Udager AM, Chiosea SI
Head Neck Pathol 2017 Sep;11(3):288-294. Epub 2017 Mar 20 doi: 10.1007/s12105-017-0798-x. PMID: 28321773 Free PMC Article

Molecular Pathology: Predictive, Prognostic, and Diagnostic Markers in Salivary Gland Tumors.

Seethala RR, Griffith CC
Surg Pathol Clin 2016 Sep;9(3):339-52. doi: 10.1016/j.path.2016.04.002. PMID: 27523965

Parotidectomy for Parotid Cancer.

Cracchiolo JR, Shaha AR
Otolaryngol Clin North Am 2016 Apr;49(2):415-24. Epub 2016 Feb 17 doi: 10.1016/j.otc.2015.10.007. PMID: 26895698 Free PMC Article

See all (313)

Recent systematic reviews

Systematic review of prognostic factors in carcinoma ex pleomorphic adenoma.

Key S, Chia C, Hasan Z, Sundaresan P, Dwivedi RC, Riffat F
Oral Oncol 2022 Oct;133:106052. Epub 2022 Jul 31 doi: 10.1016/j.oraloncology.2022.106052. PMID: 35921695

Elective neck dissection in salivary gland malignancies: Systematic review and meta-analysis.

Yan F, Lao WP, Nguyen SA, Sharma AK, Day TA
Head Neck 2022 Feb;44(2):505-517. Epub 2021 Dec 4 doi: 10.1002/hed.26923. PMID: 34862810

Clinicopathological analysis of oral and maxillofacial acinic cell carcinoma: A systematic review.

Kirschnick LB, Silveira FM, Schuch LF, Fonseca FP, Martins MAT, Lopes MA, Santos-Silva AR, Carrard VC, Dos Santos JN, Vargas PA, Wagner VP, Martins MD
J Oral Pathol Med 2021 Sep;50(8):741-749. Epub 2021 Feb 18 doi: 10.1111/jop.13159. PMID: 33455041

Systematic review of mammary analog secretory carcinoma of salivary glands at 7 years after description.

Khalele BA
Head Neck 2017 Jun;39(6):1243-1248. Epub 2017 Apr 3 doi: 10.1002/hed.24755. PMID: 28370824

Intermediate and long-term adverse effects of radioiodine therapy for differentiated thyroid carcinoma--a systematic review.

See all (13)

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Salivary Gland High Grade Carcinoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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