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Malignant superior sulcus neoplasm

MedGen UID:
107810
•Concept ID:
C0549471
•
Neoplastic Process
Synonyms: Pancoast Tumor; Tumor, Pancoast
SNOMED CT: Superior sulcus tumor (254638002); Pancoast tumor (254638002)
 
Monarch Initiative: MONDO:0006883

Definition

A malignant neoplasm originating from the apical lung. Most malignant superior sulcus neoplasms are bronchogenic carcinomas. This tumor may be associated with Pancoast syndrome. It is also known as Pancoast tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant superior sulcus neoplasm

Professional guidelines

PubMed

Discussion to: Superior sulcus non-small cell lung cancers (Pancoast tumors): Current outcomes after multidisciplinary management.
J Thorac Cardiovasc Surg 2023 Dec;166(6):1488-1489. Epub 2023 Oct 11 doi: 10.1016/j.jtcvs.2023.09.024. PMID: 37831023
Management of tumors involving the chest wall including pancoast tumors and tumors invading the spine.
Deslauriers J, Tronc F, Fortin D
Thorac Surg Clin 2013 Aug;23(3):313-25. Epub 2013 Jul 16 doi: 10.1016/j.thorsurg.2013.05.001. PMID: 23931015
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883

Recent clinical studies

Etiology

Resection of the First Rib With Preservation of the T1 Nerve Root in Pancoast Tumors of the Lung.
Filis AK, Robinson LA, Vrionis FD
Cancer Control 2016 Jul;23(3):295-301. doi: 10.1177/107327481602300313. PMID: 27556670
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Resection of superior sulcus tumors (posterior approach).
Kent MS, Bilsky MH, Rusch VW
Thorac Surg Clin 2004 May;14(2):217-28. doi: 10.1016/S1547-4127(04)00013-1. PMID: 15382298
Changes in the treatment of Pancoast tumors.
Detterbeck FC
Ann Thorac Surg 2003 Jun;75(6):1990-7. doi: 10.1016/s0003-4975(03)00134-6. PMID: 12822662
Pancoast tumor: radiation therapy alone versus preoperative radiation therapy and surgery.
Neal CR, Amdur RJ, Mendenhall WM, Knauf DG, Block AJ, Million RR
Int J Radiat Oncol Biol Phys 1991 Aug;21(3):651-60. doi: 10.1016/0360-3016(91)90683-u. PMID: 1869459

Diagnosis

Right eyelid droop.
Hellman JB, Lin LK
Eur J Intern Med 2019 Feb;60:e7-e8. Epub 2018 Jul 10 doi: 10.1016/j.ejim.2018.07.004. PMID: 30001867
Management of Lung Cancer Invading the Superior Sulcus.
Kratz JR, Woodard G, Jablons DM
Thorac Surg Clin 2017 May;27(2):149-157. doi: 10.1016/j.thorsurg.2017.01.008. PMID: 28363369
Management of Pancoast tumours.
Rusch VW
Lancet Oncol 2006 Dec;7(12):997-1005. doi: 10.1016/S1470-2045(06)70974-3. PMID: 17138221
Superior sulcus tumors and Pancoast's syndrome.
Jett JR
Lung Cancer 2003 Dec;42 Suppl 2:S17-21. doi: 10.1016/j.lungcan.2003.08.006. PMID: 14644531
Superior pulmonary sulcus tumors and Pancoast's syndrome.
Arcasoy SM, Jett JR
N Engl J Med 1997 Nov 6;337(19):1370-6. doi: 10.1056/NEJM199711063371907. PMID: 9358132

Therapy

Hybrid robotic lobectomy with thoracic wall resection for superior sulcus tumor.
Uchida S, Suzuki K, Fukui M, Hattori A, Matsunaga T, Takamochi K
Gen Thorac Cardiovasc Surg 2022 Aug;70(8):756-758. Epub 2022 Jun 6 doi: 10.1007/s11748-022-01839-x. PMID: 35666358
Horner's syndrome and epidural anesthesia in labor and cesarean section.
Vogiatzaki T, Tsikouras P, Tsoleridis T, Bachar M, Christofis C, Liberis A, Galazios G
Clin Exp Obstet Gynecol 2017;44(3):337-340. PMID: 29949268
Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Changes in the treatment of Pancoast tumors.
Detterbeck FC
Ann Thorac Surg 2003 Jun;75(6):1990-7. doi: 10.1016/s0003-4975(03)00134-6. PMID: 12822662
Pancoast tumors.
Vallières E, Karmy-Jones R, Mulligan MS, Wood DE
Curr Probl Surg 2001 May;38(5):293-376. doi: 10.1067/msg.2001.113528. PMID: 11332249

Prognosis

Cubital tunnel syndrome - a review and management guidelines.
Assmus H, Antoniadis G, Bischoff C, Hoffmann R, Martini AK, Preissler P, Scheglmann K, Schwerdtfeger K, Wessels KD, Wüstner-Hofmann M
Cent Eur Neurosurg 2011 May;72(2):90-8. Epub 2011 May 4 doi: 10.1055/s-0031-1271800. PMID: 21547883
Management of Pancoast tumours.
Rusch VW
Lancet Oncol 2006 Dec;7(12):997-1005. doi: 10.1016/S1470-2045(06)70974-3. PMID: 17138221
Superior sulcus tumors and Pancoast's syndrome.
Jett JR
Lung Cancer 2003 Dec;42 Suppl 2:S17-21. doi: 10.1016/j.lungcan.2003.08.006. PMID: 14644531
Pancoast tumors.
Vallières E, Karmy-Jones R, Mulligan MS, Wood DE
Curr Probl Surg 2001 May;38(5):293-376. doi: 10.1067/msg.2001.113528. PMID: 11332249
Superior pulmonary sulcus tumors and Pancoast's syndrome.
Arcasoy SM, Jett JR
N Engl J Med 1997 Nov 6;337(19):1370-6. doi: 10.1056/NEJM199711063371907. PMID: 9358132

Clinical prediction guides

Horner's syndrome and epidural anesthesia in labor and cesarean section.
Vogiatzaki T, Tsikouras P, Tsoleridis T, Bachar M, Christofis C, Liberis A, Galazios G
Clin Exp Obstet Gynecol 2017;44(3):337-340. PMID: 29949268
Eponyms in cardiothoracic radiology: Part I. Neoplasms.
Mohammed TL, Saettele MR, Saettele T, Patel V, Kanne JP
Curr Probl Diagn Radiol 2014 Mar-Apr;43(2):91-8. doi: 10.1067/j.cpradiol.2013.12.003. PMID: 24629662
CT-guided percutaneous cordotomy for intractable pain in what is more than a disease: lung malignancies.
Kanpolat Y, Ozdemir M, Al-Beyati E
Turk Neurosurg 2013;23(1):81-7. doi: 10.5137/1019-5149.JTN.6980-12.0. PMID: 23344872
Ultrasonography of Pancoast tumor.
Yang PC, Lee LN, Luh KT, Kuo SH, Yang SP
Chest 1988 Jul;94(1):124-8. doi: 10.1378/chest.94.1.124. PMID: 3289832
Microsurgical DREZ-lesion in the treatment of deafferentation pain.
Esposito S, Delitala A, Nardi PV
J Neurosurg Sci 1988 Jul-Sep;32(3):113-5. PMID: 2465395

Recent systematic reviews

Management of locally advanced pancoast (superior sulcus) tumors with spine involvement.
Setzer M, Robinson LA, Vrionis FD
Cancer Control 2014 Apr;21(2):158-67. doi: 10.1177/107327481402100209. PMID: 24667403

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