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Purulent drainage from skin

MedGen UID:
1056319
•Concept ID:
CN378793
•
Finding
HPO: HP:6001119

Definition

Exudation of a thick, opaque fluid from a wound or skin lesion, typically as a result of infection and taining pus, i.e., dead white blood cells, bacteria, and tissue debris. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPurulent drainage from skin

Professional guidelines

PubMed

Omphalitis: Clinical Presentation and Approach to Evaluation and Management.
Kaplan RL
Pediatr Emerg Care 2023 Mar 1;39(3):188-189. doi: 10.1097/PEC.0000000000002918. PMID: 36853079
Skin Infections and Outpatient Burn Management: Bacterial Skin Infections.
Trelease-Bell A
FP Essent 2020 Feb;489:11-15. PMID: 31995349
Prepatellar and olecranon bursitis: literature review and development of a treatment algorithm.
Baumbach SF, Lobo CM, Badyine I, Mutschler W, Kanz KG
Arch Orthop Trauma Surg 2014 Mar;134(3):359-70. Epub 2013 Dec 5 doi: 10.1007/s00402-013-1882-7. PMID: 24305696

Recent clinical studies

Etiology

Omphalitis: Clinical Presentation and Approach to Evaluation and Management.
Kaplan RL
Pediatr Emerg Care 2023 Mar 1;39(3):188-189. doi: 10.1097/PEC.0000000000002918. PMID: 36853079
Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series.
Frechet L, Puzenat E, Charollais R, Dresco F, Carlet C, Gallais-Serezal I, Nardin C, Aubin F
Eur J Dermatol 2021 Feb 1;31(1):81-85. doi: 10.1684/ejd.2021.3969. PMID: 33648906
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Skin Infections and Outpatient Burn Management: Bacterial Skin Infections.
Trelease-Bell A
FP Essent 2020 Feb;489:11-15. PMID: 31995349
Ultrasound features of purulent skin and soft tissue infection without abscess.
Nelson CE, Chen AE, Bellah RD, Biko DM, Ho-Fung VM, Francavilla ML, Xiao R, Kaplan SL
Emerg Radiol 2018 Oct;25(5):505-511. Epub 2018 Jun 6 doi: 10.1007/s10140-018-1612-0. PMID: 29876711

Diagnosis

Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Emerging medical treatments for hidradenitis suppurativa.
Lyons AB, Shabeeb N, Nicholson CL, Braunberger TL, Peacock A, Hamzavi IH
J Am Acad Dermatol 2020 Aug;83(2):554-562. Epub 2020 Apr 11 doi: 10.1016/j.jaad.2020.04.009. PMID: 32289386
Skin and Soft Tissue Infections in the Emergency Department.
Breyre A, Frazee BW
Emerg Med Clin North Am 2018 Nov;36(4):723-750. doi: 10.1016/j.emc.2018.06.005. PMID: 30297001
Deep Granuloma Annulare Mimicking Inflamed Cysts in a Teenager.
Guo EL, Degesys CA, Jahan-Tigh R, Chan A
Pediatr Dermatol 2017 Jul;34(4):e207-e208. Epub 2017 Apr 17 doi: 10.1111/pde.13137. PMID: 28419540
Clinical inquiries. When should you suspect community-acquired MRSA? How should you treat it?
May TJ, Safranek S
J Fam Pract 2009 May;58(5):276, 278. PMID: 19442392

Therapy

Common Skin Conditions in Children and Adolescents: Bacterial Infections.
Zha M, Usatine R
FP Essent 2024 Jun;541:14-19. PMID: 38896826
Omphalitis: Clinical Presentation and Approach to Evaluation and Management.
Kaplan RL
Pediatr Emerg Care 2023 Mar 1;39(3):188-189. doi: 10.1097/PEC.0000000000002918. PMID: 36853079
Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series.
Frechet L, Puzenat E, Charollais R, Dresco F, Carlet C, Gallais-Serezal I, Nardin C, Aubin F
Eur J Dermatol 2021 Feb 1;31(1):81-85. doi: 10.1684/ejd.2021.3969. PMID: 33648906
Staphylococcal Skin and Soft Tissue Infections.
Hatlen TJ, Miller LG
Infect Dis Clin North Am 2021 Mar;35(1):81-105. Epub 2020 Dec 7 doi: 10.1016/j.idc.2020.10.003. PMID: 33303329
Emerging medical treatments for hidradenitis suppurativa.
Lyons AB, Shabeeb N, Nicholson CL, Braunberger TL, Peacock A, Hamzavi IH
J Am Acad Dermatol 2020 Aug;83(2):554-562. Epub 2020 Apr 11 doi: 10.1016/j.jaad.2020.04.009. PMID: 32289386

Prognosis

Skin and Soft Tissue Infections in the Emergency Department.
Breyre A, Frazee BW
Emerg Med Clin North Am 2018 Nov;36(4):723-750. doi: 10.1016/j.emc.2018.06.005. PMID: 30297001
Methicillin-resistant Staphylococcus aureus infection in the hand.
Harrison B, Ben-Amotz O, Sammer DM
Plast Reconstr Surg 2015 Mar;135(3):826-830. doi: 10.1097/PRS.0000000000000952. PMID: 25719701
Management and outcome of adults with skin and soft tissue infection caused by methicillin-resistant Staphylococcus aureus in a tertiary hospital in central Taiwan.
Teh SH, Chi CY, Lin PC, Ho CM, Chou CH, Tsai CT, Wang JH, Ho MW
J Microbiol Immunol Infect 2015 Oct;48(5):497-503. Epub 2014 Nov 12 doi: 10.1016/j.jmii.2014.08.030. PMID: 25446039
Diabetic foot infections: stepwise medical and surgical management.
Armstrong DG, Lipsky BA
Int Wound J 2004 Jun;1(2):123-32. doi: 10.1111/j.1742-4801.2004.00035.x. PMID: 16722884Free PMC Article
Failure of intravenous antibiotic therapy of multiple temporal brain abscesses due to Propionibacterium acnes requiring temporal lobectomy.
Senneville E, Savage C, Lamy O, Fawaz A, Bourez J, Ajana F, Dubreuil L, Chidiac C, Mouton Y
J Infect 1997 May;34(3):269-71. doi: 10.1016/s0163-4453(97)94479-0. PMID: 9200038

Clinical prediction guides

Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series.
Frechet L, Puzenat E, Charollais R, Dresco F, Carlet C, Gallais-Serezal I, Nardin C, Aubin F
Eur J Dermatol 2021 Feb 1;31(1):81-85. doi: 10.1684/ejd.2021.3969. PMID: 33648906
Sonographically Occult Abscesses of the Buttock and Perineum in Children.
Nelson CE, Kaplan S, Bellah RD, Chen AE
Pediatr Emerg Care 2021 Dec 1;37(12):e910-e914. doi: 10.1097/PEC.0000000000001294. PMID: 28953103
Ultrasound features of purulent skin and soft tissue infection without abscess.
Nelson CE, Chen AE, Bellah RD, Biko DM, Ho-Fung VM, Francavilla ML, Xiao R, Kaplan SL
Emerg Radiol 2018 Oct;25(5):505-511. Epub 2018 Jun 6 doi: 10.1007/s10140-018-1612-0. PMID: 29876711
Risk factors for nonpurulent leg cellulitis: a systematic review and meta-analysis.
Quirke M, Ayoub F, McCabe A, Boland F, Smith B, O'Sullivan R, Wakai A
Br J Dermatol 2017 Aug;177(2):382-394. Epub 2017 Jul 25 doi: 10.1111/bjd.15186. PMID: 27864837
Detection and initial management of complicated skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus.
Sawyer RG
Surg Infect (Larchmt) 2008;9 Suppl 1:s11-5. doi: 10.1089/sur.2008.064.supp. PMID: 18844470

Recent systematic reviews

Risk factors for nonpurulent leg cellulitis: a systematic review and meta-analysis.
Quirke M, Ayoub F, McCabe A, Boland F, Smith B, O'Sullivan R, Wakai A
Br J Dermatol 2017 Aug;177(2):382-394. Epub 2017 Jul 25 doi: 10.1111/bjd.15186. PMID: 27864837
Prepatellar and olecranon bursitis: literature review and development of a treatment algorithm.
Baumbach SF, Lobo CM, Badyine I, Mutschler W, Kanz KG
Arch Orthop Trauma Surg 2014 Mar;134(3):359-70. Epub 2013 Dec 5 doi: 10.1007/s00402-013-1882-7. PMID: 24305696

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