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Filum terminale lipoma

MedGen UID:
1053287
•Concept ID:
CN376697
•
Finding
Synonyms: Fatty filum terminale; LFT; Lipoma of filum terminale; Lipoma of the filum terminale
 
HPO: HP:6000184

Definition

Filum terminale lipomas (FTLs) are a type of lumbosacral lipoma in which the fat is entirely within the filum terminale and separate from the conus medullaris. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFilum terminale lipoma

Conditions with this feature

Microcephaly 25, primary, autosomal recessive
MedGen UID:
1674123
•Concept ID:
C5193046
•
Disease or Syndrome
See: Condition Record
Microcephaly 25, primary, autosomal recessive

Professional guidelines

PubMed

Spinal cord anomalies in patients with anorectal malformations without severe sacral abnormalities or meningomyelocele: outcomes after expectant, conservative management.
Kyrklund K, Pakarinen MP, Taskinen S, Kivisaari R, Rintala RJ
J Neurosurg Spine 2016 Dec;25(6):782-789. Epub 2016 Jul 22 doi: 10.3171/2016.4.SPINE1641. PMID: 27448173

Recent clinical studies

Etiology

Role of Magnetic Resonance Imaging in the Screening of Closed Spinal Dysraphism.
Aoki H, Mugikura S, Shirane R, Hayashi T, Kimiwada T, Sakai K, Ainoya K, Ota H, Takase K, Shimanuki Y
Neurol Med Chir (Tokyo) 2023 Oct 15;63(10):473-481. Epub 2023 Aug 30 doi: 10.2176/jns-nmc.2023-0002. PMID: 37648539Free PMC Article
Fibrofatty filum terminale: long-term outcomes from a Singapore children's hospital.
Lim JX, Fong E, Goh C, Ng LP, Merchant K, Low DCY, Seow WT, Low SYY
J Neurosurg Pediatr 2023 Mar 1;31(3):197-205. Epub 2022 Dec 2 doi: 10.3171/2022.8.PEDS22103. PMID: 36461829
Filum terminale lipoma revealed by screening spinal ultrasonography in infants with simple sacral dimple.
Oh JE, Lim GY, Kim HW, Kim SY
Childs Nerv Syst 2020 May;36(5):1037-1042. Epub 2019 Dec 5 doi: 10.1007/s00381-019-04430-7. PMID: 31807897
Minimally Invasive Surgical Approach to Filum Lipoma.
Hayashi T, Kimiwada T, Kohama M, Shirane R, Tominaga T
Neurol Med Chir (Tokyo) 2018 Mar 15;58(3):132-137. Epub 2018 Jan 23 doi: 10.2176/nmc.oa.2017-0200. PMID: 29367470Free PMC Article
Optimal Filum Terminale Thickness Cutoff Value on Sonography for Lipoma Screening in Young Children.
Shin HJ, Kim MJ, Lee HS, Kim HG, Lee MJ
J Ultrasound Med 2015 Nov;34(11):1943-9. Epub 2015 Sep 18 doi: 10.7863/ultra.14.10079. PMID: 26384611

Diagnosis

Incidence of Tethered Cord Syndrome in Pediatric Patients With Neurofibromatosis Type 1.
Han Y, Wang H, Huang Y
World Neurosurg 2024 Nov;191:e707-e712. Epub 2024 Sep 11 doi: 10.1016/j.wneu.2024.09.027. PMID: 39270790
Beyond the abdominal and pelvic cavity: abdominal wall and spinal "Aunt Minnies".
Thompson R, Vahdat N, Alshehri W, Aganovic L, Baig S, Mirza S, Cassidy H, Hughes F
Abdom Radiol (NY) 2023 Apr;48(4):1479-1504. Epub 2023 Feb 15 doi: 10.1007/s00261-023-03830-3. PMID: 36790455Free PMC Article
Filum terminale lipoma revealed by screening spinal ultrasonography in infants with simple sacral dimple.
Oh JE, Lim GY, Kim HW, Kim SY
Childs Nerv Syst 2020 May;36(5):1037-1042. Epub 2019 Dec 5 doi: 10.1007/s00381-019-04430-7. PMID: 31807897
Combined Spinal Arteriovenous Malformation and Spinal Dysraphism.
Islak C, Kandemirli SG, Kizilkilic O, Kocer N, Tuzgen S, Hanci MM
World Neurosurg 2018 Feb;110:407-413. Epub 2017 Dec 6 doi: 10.1016/j.wneu.2017.11.162. PMID: 29223517
Optimal Filum Terminale Thickness Cutoff Value on Sonography for Lipoma Screening in Young Children.
Shin HJ, Kim MJ, Lee HS, Kim HG, Lee MJ
J Ultrasound Med 2015 Nov;34(11):1943-9. Epub 2015 Sep 18 doi: 10.7863/ultra.14.10079. PMID: 26384611

Therapy

Early onset scoliosis with intraspinal anomalies: management with growing rod.
Jayaswal A, Kandwal P, Goswami A, Vijayaraghavan G, Jariyal A, Upendra BN, Gupta A
Eur Spine J 2016 Oct;25(10):3301-3307. Epub 2016 Apr 12 doi: 10.1007/s00586-016-4566-5. PMID: 27072552

Prognosis

Incidence of Tethered Cord Syndrome in Pediatric Patients With Neurofibromatosis Type 1.
Han Y, Wang H, Huang Y
World Neurosurg 2024 Nov;191:e707-e712. Epub 2024 Sep 11 doi: 10.1016/j.wneu.2024.09.027. PMID: 39270790
Spinal cord anomalies in patients with anorectal malformations without severe sacral abnormalities or meningomyelocele: outcomes after expectant, conservative management.
Kyrklund K, Pakarinen MP, Taskinen S, Kivisaari R, Rintala RJ
J Neurosurg Spine 2016 Dec;25(6):782-789. Epub 2016 Jul 22 doi: 10.3171/2016.4.SPINE1641. PMID: 27448173
Radiological predictors of neurological compromise in adults with filum terminale lipoma.
Al-Habib AF, Al-Rashidi SM, Al-Badr FB, Hassan HH
Neurosciences (Riyadh) 2013 Apr;18(2):180-2. PMID: 23545622
Unusual association of tethered cord, filum terminale lipoma, and myxopapillary ependymoma.
Donmez FY, Basaran C, Ulu EM, Guvenc Z, Tarhan NC
Spine (Phila Pa 1976) 2008 Oct 15;33(22):E849-51. doi: 10.1097/BRS.0b013e318187ff55. PMID: 18923308

Clinical prediction guides

Fibrofatty filum terminale: long-term outcomes from a Singapore children's hospital.
Lim JX, Fong E, Goh C, Ng LP, Merchant K, Low DCY, Seow WT, Low SYY
J Neurosurg Pediatr 2023 Mar 1;31(3):197-205. Epub 2022 Dec 2 doi: 10.3171/2022.8.PEDS22103. PMID: 36461829
Filum terminale lipoma revealed by screening spinal ultrasonography in infants with simple sacral dimple.
Oh JE, Lim GY, Kim HW, Kim SY
Childs Nerv Syst 2020 May;36(5):1037-1042. Epub 2019 Dec 5 doi: 10.1007/s00381-019-04430-7. PMID: 31807897
Spinal cord anomalies in patients with anorectal malformations without severe sacral abnormalities or meningomyelocele: outcomes after expectant, conservative management.
Kyrklund K, Pakarinen MP, Taskinen S, Kivisaari R, Rintala RJ
J Neurosurg Spine 2016 Dec;25(6):782-789. Epub 2016 Jul 22 doi: 10.3171/2016.4.SPINE1641. PMID: 27448173
Optimal Filum Terminale Thickness Cutoff Value on Sonography for Lipoma Screening in Young Children.
Shin HJ, Kim MJ, Lee HS, Kim HG, Lee MJ
J Ultrasound Med 2015 Nov;34(11):1943-9. Epub 2015 Sep 18 doi: 10.7863/ultra.14.10079. PMID: 26384611
Radiological predictors of neurological compromise in adults with filum terminale lipoma.
Al-Habib AF, Al-Rashidi SM, Al-Badr FB, Hassan HH
Neurosciences (Riyadh) 2013 Apr;18(2):180-2. PMID: 23545622

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