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Thumb hypoplasia grade 4

MedGen UID:
1053249
•Concept ID:
CN378294
•
Finding
Synonyms: Floating thumb; Hypoplasia of the thumb grade IV
 
HPO: HP:6000942

Definition

A type of developmental undergrowth of the thumb characterized by attachment to the hand only by the skin and digital neurovascular structures. [from HPO]

Professional guidelines

PubMed

Classification and surgical treatment of symphalangism in interphalangeal joints of the hand.
Baek GH, Lee HJ
Clin Orthop Surg 2012 Mar;4(1):58-65. Epub 2012 Feb 20 doi: 10.4055/cios.2012.4.1.58. PMID: 22379556Free PMC Article

Recent clinical studies

Etiology

Mermaid syndrome: Rare genetic anomaly.
Javed HS, Khalid MI
J Pak Med Assoc 2023 Apr;73(4):915-918. doi: 10.47391/JPMA.6073. PMID: 37052015
Epidemiology of cervical human papillomavirus (HPV) infection and squamous intraepithelial lesions (SIL) among a cohort of HIV-infected and uninfected Ghanaian women.
Obiri-Yeboah D, Akakpo PK, Mutocheluh M, Adjei-Danso E, Allornuvor G, Amoako-Sakyi D, Adu-Sarkodie Y, Mayaud P
BMC Cancer 2017 Oct 16;17(1):688. doi: 10.1186/s12885-017-3682-x. PMID: 29037188Free PMC Article
Oblique Osteotomy for the Correction of the Zigzag Deformity of Wassel Type IV Polydactyly.
Kim BJ, Choi JH, Kwon ST
Plast Reconstr Surg 2017 Dec;140(6):1220-1228. doi: 10.1097/PRS.0000000000003877. PMID: 28820841
Rare cytogenetic abnormalities in acute myeloid leukemia transformed from Fanconi anemia - a case report.
Hussain S, Adil SN
BMC Res Notes 2013 Aug 12;6:316. doi: 10.1186/1756-0500-6-316. PMID: 23937881Free PMC Article
The natural history of adult trigger thumb.
Schofield CB, Citron ND
J Hand Surg Br 1993 Apr;18(2):247-8. doi: 10.1016/0266-7681(93)90120-5. PMID: 8501386

Diagnosis

Mermaid syndrome: Rare genetic anomaly.
Javed HS, Khalid MI
J Pak Med Assoc 2023 Apr;73(4):915-918. doi: 10.47391/JPMA.6073. PMID: 37052015
Congenital Great Toe Hypoplasia Equivalent to a Grade 3 Hypoplastic Thumb in a Patient with VACTERL Association.
Mende K, Tonkin MA
J Hand Surg Asian Pac Vol 2018 Dec;23(4):605-606. doi: 10.1142/S2424835518720402. PMID: 30428812
Classification and surgical treatment of symphalangism in interphalangeal joints of the hand.
Baek GH, Lee HJ
Clin Orthop Surg 2012 Mar;4(1):58-65. Epub 2012 Feb 20 doi: 10.4055/cios.2012.4.1.58. PMID: 22379556Free PMC Article

Therapy

Botulinum toxin type A in the treatment of focal hand dystonia after surgical treatment for thumb duplication.
Santamato A, Panza F, Solfrizzi V, Frisardi V, Moretti B, Notarnicola A, Neve A, Ranieri M, Fiore P
Orthopedics 2009 Jul;32(7):529. doi: 10.3928/01477447-20090527-07. PMID: 19634837

Prognosis

Precision grip with congenital hypoplasty or hypofunction of the thumb.
Smrcka V, Dylevský I, Kuklík M
Acta Chir Plast 1999;41(4):107-11. PMID: 10743713
The natural history of adult trigger thumb.
Schofield CB, Citron ND
J Hand Surg Br 1993 Apr;18(2):247-8. doi: 10.1016/0266-7681(93)90120-5. PMID: 8501386

Clinical prediction guides

Double Vascularized Fibula Proximal Growth Plate Transplantation: Novel Technique for the Radial Longitudinal Deficiency (RLD) Grade IV Reconstruction.
Ozols D, Butnere MM, Kalnina L, Mokanu A, Ozola S, Mikitins A, Petersons A
Tech Hand Up Extrem Surg 2022 Jun 1;26(2):98-102. doi: 10.1097/BTH.0000000000000366. PMID: 34411041
Oblique Osteotomy for the Correction of the Zigzag Deformity of Wassel Type IV Polydactyly.
Kim BJ, Choi JH, Kwon ST
Plast Reconstr Surg 2017 Dec;140(6):1220-1228. doi: 10.1097/PRS.0000000000003877. PMID: 28820841
Botulinum toxin type A in the treatment of focal hand dystonia after surgical treatment for thumb duplication.
Santamato A, Panza F, Solfrizzi V, Frisardi V, Moretti B, Notarnicola A, Neve A, Ranieri M, Fiore P
Orthopedics 2009 Jul;32(7):529. doi: 10.3928/01477447-20090527-07. PMID: 19634837

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