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Social anxiety

MedGen UID:
1052790
•Concept ID:
CN376543
•
Finding
HPO: HP:6000029

Definition

Excessive fear of embarrassment, humiliation, or rejection when exposed to possible negative evaluation by others when engaged in a public performance or social interaction. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSocial anxiety

Professional guidelines

PubMed

Treatment of anxiety disorders.
Bandelow B, Michaelis S, Wedekind D
Dialogues Clin Neurosci 2017 Jun;19(2):93-107. doi: 10.31887/DCNS.2017.19.2/bbandelow. PMID: 28867934Free PMC Article
Cannabidiol as a Potential Treatment for Anxiety Disorders.
Blessing EM, Steenkamp MM, Manzanares J, Marmar CR
Neurotherapeutics 2015 Oct;12(4):825-36. doi: 10.1007/s13311-015-0387-1. PMID: 26341731Free PMC Article
Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.
Katzman MA, Bleau P, Blier P, Chokka P, Kjernisted K, Van Ameringen M; Canadian Anxiety Guidelines Initiative Group on behalf of the Anxiety Disorders Association of Canada/Association Canadienne des troubles anxieux and McGill University, Antony MM, Bouchard S, Brunet A, Flament M, Grigoriadis S, Mendlowitz S, O'Connor K, Rabheru K, Richter PM, Robichaud M, Walker JR
BMC Psychiatry 2014;14 Suppl 1(Suppl 1):S1. Epub 2014 Jul 2 doi: 10.1186/1471-244X-14-S1-S1. PMID: 25081580Free PMC Article

Recent clinical studies

Etiology

Long-term outcomes of cognitive behavioural therapy for social anxiety disorder: A meta-analysis of randomised controlled trials.
Kindred R, Bates GW, McBride NL
J Anxiety Disord 2022 Dec;92:102640. Epub 2022 Oct 13 doi: 10.1016/j.janxdis.2022.102640. PMID: 36265270
Understanding Social Anxiety Disorder in Adolescents and Improving Treatment Outcomes: Applying the Cognitive Model of Clark and Wells (1995).
Leigh E, Clark DM
Clin Child Fam Psychol Rev 2018 Sep;21(3):388-414. doi: 10.1007/s10567-018-0258-5. PMID: 29654442Free PMC Article
A systematic review of adult attachment and social anxiety.
Manning RP, Dickson JM, Palmier-Claus J, Cunliffe A, Taylor PJ
J Affect Disord 2017 Mar 15;211:44-59. Epub 2016 Dec 19 doi: 10.1016/j.jad.2016.12.020. PMID: 28088057
Exposure to virtual social interactions in the treatment of social anxiety disorder: A randomized controlled trial.
Kampmann IL, Emmelkamp PM, Hartanto D, Brinkman WP, Zijlstra BJ, Morina N
Behav Res Ther 2016 Feb;77:147-56. Epub 2015 Dec 29 doi: 10.1016/j.brat.2015.12.016. PMID: 26752328
Social anxiety and social anxiety disorder.
Morrison AS, Heimberg RG
Annu Rev Clin Psychol 2013;9:249-74. doi: 10.1146/annurev-clinpsy-050212-185631. PMID: 23537485

Diagnosis

Understanding Social Anxiety Disorder in Adolescents and Improving Treatment Outcomes: Applying the Cognitive Model of Clark and Wells (1995).
Leigh E, Clark DM
Clin Child Fam Psychol Rev 2018 Sep;21(3):388-414. doi: 10.1007/s10567-018-0258-5. PMID: 29654442Free PMC Article
Gaze-Based Assessments of Vigilance and Avoidance in Social Anxiety: a Review.
Chen NTM, Clarke PJF
Curr Psychiatry Rep 2017 Sep;19(9):59. doi: 10.1007/s11920-017-0808-4. PMID: 28726063
Gender differences in social anxiety disorder: A review.
Asher M, Asnaani A, Aderka IM
Clin Psychol Rev 2017 Aug;56:1-12. Epub 2017 May 30 doi: 10.1016/j.cpr.2017.05.004. PMID: 28578248
Exposure to virtual social interactions in the treatment of social anxiety disorder: A randomized controlled trial.
Kampmann IL, Emmelkamp PM, Hartanto D, Brinkman WP, Zijlstra BJ, Morina N
Behav Res Ther 2016 Feb;77:147-56. Epub 2015 Dec 29 doi: 10.1016/j.brat.2015.12.016. PMID: 26752328
Social anxiety disorder in DSM-5.
Heimberg RG, Hofmann SG, Liebowitz MR, Schneier FR, Smits JA, Stein MB, Hinton DE, Craske MG
Depress Anxiety 2014 Jun;31(6):472-9. Epub 2014 Jan 2 doi: 10.1002/da.22231. PMID: 24395386

Therapy

Evaluation of Cognitive Behavioral Therapy vs Mindfulness Meditation in Brain Changes During Reappraisal and Acceptance Among Patients With Social Anxiety Disorder: A Randomized Clinical Trial.
Goldin PR, Thurston M, Allende S, Moodie C, Dixon ML, Heimberg RG, Gross JJ
JAMA Psychiatry 2021 Oct 1;78(10):1134-1142. doi: 10.1001/jamapsychiatry.2021.1862. PMID: 34287622Free PMC Article
Use of cannabidiol in anxiety and anxiety-related disorders.
Skelley JW, Deas CM, Curren Z, Ennis J
J Am Pharm Assoc (2003) 2020 Jan-Feb;60(1):253-261. Epub 2019 Dec 19 doi: 10.1016/j.japh.2019.11.008. PMID: 31866386
Long-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders: A Systematic Review and Meta-analysis.
van Dis EAM, van Veen SC, Hagenaars MA, Batelaan NM, Bockting CLH, van den Heuvel RM, Cuijpers P, Engelhard IM
JAMA Psychiatry 2020 Mar 1;77(3):265-273. doi: 10.1001/jamapsychiatry.2019.3986. PMID: 31758858Free PMC Article
Cognitive behavioral therapy for anxiety and related disorders: A meta-analysis of randomized placebo-controlled trials.
Carpenter JK, Andrews LA, Witcraft SM, Powers MB, Smits JAJ, Hofmann SG
Depress Anxiety 2018 Jun;35(6):502-514. Epub 2018 Feb 16 doi: 10.1002/da.22728. PMID: 29451967Free PMC Article
Stuttering: Clinical and research update.
Perez HR, Stoeckle JH
Can Fam Physician 2016 Jun;62(6):479-84. PMID: 27303004Free PMC Article

Prognosis

Therapist-Guided Internet-Delivered Cognitive Behavioral Therapy vs Internet-Delivered Supportive Therapy for Children and Adolescents With Social Anxiety Disorder: A Randomized Clinical Trial.
Nordh M, Wahlund T, Jolstedt M, Sahlin H, Bjureberg J, Ahlen J, Lalouni M, Salomonsson S, Vigerland S, Lavner M, Öst LG, Lenhard F, Hesser H, Mataix-Cols D, Högström J, Serlachius E
JAMA Psychiatry 2021 Jul 1;78(7):705-713. doi: 10.1001/jamapsychiatry.2021.0469. PMID: 33978699Free PMC Article
Social Anxiety and Empathy: A Systematic Review and Meta-analysis.
Pittelkow MM, Aan Het Rot M, Seidel LJ, Feyel N, Roest AM
J Anxiety Disord 2021 Mar;78:102357. Epub 2021 Jan 20 doi: 10.1016/j.janxdis.2021.102357. PMID: 33588287
Long-term effectiveness of cognitive behavioral therapy for youth with anxiety disorders.
Kodal A, Fjermestad K, Bjelland I, Gjestad R, Öst LG, Bjaastad JF, Haugland BSM, Havik OE, Heiervang E, Wergeland GJ
J Anxiety Disord 2018 Jan;53:58-67. Epub 2017 Nov 26 doi: 10.1016/j.janxdis.2017.11.003. PMID: 29195188
Virtual reality exposure therapy for social anxiety disorder: a randomized controlled trial.
Anderson PL, Price M, Edwards SM, Obasaju MA, Schmertz SK, Zimand E, Calamaras MR
J Consult Clin Psychol 2013 Oct;81(5):751-60. Epub 2013 Jun 24 doi: 10.1037/a0033559. PMID: 23796315
Prevalence and development of psychiatric disorders in childhood and adolescence.
Costello EJ, Mustillo S, Erkanli A, Keeler G, Angold A
Arch Gen Psychiatry 2003 Aug;60(8):837-44. doi: 10.1001/archpsyc.60.8.837. PMID: 12912767

Clinical prediction guides

Social Anxiety and Empathy: A Systematic Review and Meta-analysis.
Pittelkow MM, Aan Het Rot M, Seidel LJ, Feyel N, Roest AM
J Anxiety Disord 2021 Mar;78:102357. Epub 2021 Jan 20 doi: 10.1016/j.janxdis.2021.102357. PMID: 33588287
Social Anxiety and Depression Stigma Among Adolescents.
Lynch H, McDonagh C, Hennessy E
J Affect Disord 2021 Feb 15;281:744-750. Epub 2020 Nov 14 doi: 10.1016/j.jad.2020.11.073. PMID: 33257039
Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study.
Danforth AL, Grob CS, Struble C, Feduccia AA, Walker N, Jerome L, Yazar-Klosinski B, Emerson A
Psychopharmacology (Berl) 2018 Nov;235(11):3137-3148. Epub 2018 Sep 8 doi: 10.1007/s00213-018-5010-9. PMID: 30196397Free PMC Article
The role of social isolation in social anxiety disorder: a systematic review and meta-analysis.
Teo AR, Lerrigo R, Rogers MA
J Anxiety Disord 2013 May;27(4):353-64. Epub 2013 Apr 16 doi: 10.1016/j.janxdis.2013.03.010. PMID: 23746493
Paroxetine controlled release.
Bang LM, Keating GM
CNS Drugs 2004;18(6):355-64; discussion 365-6. doi: 10.2165/00023210-200418060-00003. PMID: 15089103

Recent systematic reviews

Virtual reality in the diagnostic and therapy for mental disorders: A systematic review.
Wiebe A, Kannen K, Selaskowski B, Mehren A, Thöne AK, Pramme L, Blumenthal N, Li M, Asché L, Jonas S, Bey K, Schulze M, Steffens M, Pensel MC, Guth M, Rohlfsen F, Ekhlas M, Lügering H, Fileccia H, Pakos J, Lux S, Philipsen A, Braun N
Clin Psychol Rev 2022 Dec;98:102213. Epub 2022 Oct 30 doi: 10.1016/j.cpr.2022.102213. PMID: 36356351
Social anxiety and behavioral assessments of social cognition: A systematic review.
Alvi T, Kumar D, Tabak BA
J Affect Disord 2022 Aug 15;311:17-30. Epub 2022 Apr 28 doi: 10.1016/j.jad.2022.04.130. PMID: 35490878Free PMC Article
Mindfulness-based interventions for social anxiety disorder: A systematic review and meta-analysis.
Liu X, Yi P, Ma L, Liu W, Deng W, Yang X, Liang M, Luo J, Li N, Li X
Psychiatry Res 2021 Jun;300:113935. Epub 2021 Apr 20 doi: 10.1016/j.psychres.2021.113935. PMID: 33895444
A systematic review of adult attachment and social anxiety.
Manning RP, Dickson JM, Palmier-Claus J, Cunliffe A, Taylor PJ
J Affect Disord 2017 Mar 15;211:44-59. Epub 2016 Dec 19 doi: 10.1016/j.jad.2016.12.020. PMID: 28088057
The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review.
Kroenke K, Spitzer RL, Williams JB, Löwe B
Gen Hosp Psychiatry 2010 Jul-Aug;32(4):345-59. Epub 2010 May 7 doi: 10.1016/j.genhosppsych.2010.03.006. PMID: 20633738

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Table of contents

    Clinical resources

    Practice guidelines

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