U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cancrum oris

MedGen UID:
10366
Concept ID:
C0028271
Disease or Syndrome
Synonyms: Noma; Noma neonatorum; Oral gangrene; Oro-facial gangrene; Oro-facial noma
SNOMED CT: Cancrum oris (18116006); Gangrenous stomatitis (18116006); Noma (18116006); Acute gangrenous stomatitis (18116006)
 
Monarch Initiative: MONDO:0017124
Orphanet: ORPHA2700

Definition

Noma is a gangrenous disease that causes severe destruction of the soft and osseous tissues of the face. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCancrum oris
Follow this link to review classifications for Cancrum oris in Orphanet.

Professional guidelines

PubMed

Rüegg EM, Baratti-Mayer D, Jaquinet A, Montandon D, Pittet-Cuénod B
Int J Oral Maxillofac Surg 2018 Dec;47(12):1527-1533. Epub 2018 Aug 10 doi: 10.1016/j.ijom.2018.07.012. PMID: 30104131
SHRAND H
Clin Proc 1947 Jul;6(5):197-203. PMID: 20261264
SHIRCORE JO
East Afr Med J 1947 May;24(5):202. PMID: 20255595

Recent clinical studies

Etiology

Crecelius EM, Burnett MW
J Spec Oper Med 2020 Summer;20(2):136-138. doi: 10.55460/3NFC-341T. PMID: 32573751
Shaye DA, Winters R, Rabbels J, Adentunji AS, Magee A, Vo D
Laryngoscope 2019 Jan;129(1):96-99. Epub 2018 Sep 8 doi: 10.1002/lary.27230. PMID: 30194753
Ashok N, Tarakji B, Darwish S, Rodrigues JC, Altamimi MA
Glob J Health Sci 2015 Jul 30;8(4):53-9. doi: 10.5539/gjhs.v8n4p53. PMID: 26573028Free PMC Article
Enwonwu CO, Falkler WA Jr, Phillips RS
Lancet 2006 Jul 8;368(9530):147-56. doi: 10.1016/S0140-6736(06)69004-1. PMID: 16829299
Adolph HP, Yugueros P, Woods JE
Ann Plast Surg 1996 Dec;37(6):657-68. doi: 10.1097/00000637-199612000-00017. PMID: 8988783

Diagnosis

Gupta A, Sardana K, Gautam RK
Trop Doct 2018 Jul;48(3):230-232. Epub 2018 Jan 25 doi: 10.1177/0049475518754720. PMID: 29368993
Sykes LM, Essop RM
J Prosthet Dent 2000 Jun;83(6):613-6. PMID: 10842126
Falkler WA Jr, Enwonwu CO, Idigbe EO
Oral Dis 1999 Apr;5(2):150-5. doi: 10.1111/j.1601-0825.1999.tb00081.x. PMID: 10522213
Adolph HP, Yugueros P, Woods JE
Ann Plast Surg 1996 Dec;37(6):657-68. doi: 10.1097/00000637-199612000-00017. PMID: 8988783
Sawyer DR, Nwoku AL
ASDC J Dent Child 1981 Mar-Apr;48(2):138-41. PMID: 6938548

Therapy

Crecelius EM, Burnett MW
J Spec Oper Med 2020 Summer;20(2):136-138. doi: 10.55460/3NFC-341T. PMID: 32573751
Dahlén G, Ebenfelt A
Expert Rev Anti Infect Ther 2011 Feb;9(2):227-36. doi: 10.1586/eri.10.172. PMID: 21342070
Nash ES, Cheng LH, Smart K
Br J Oral Maxillofac Surg 1991 Feb;29(1):51-3. doi: 10.1016/0266-4356(91)90176-6. PMID: 1900721
Hansen DA
S Afr Med J 1972 Apr 1;46(14):392-4. PMID: 5025246
Tempest MN
Br J Surg 1966 Nov;53(11):949-69. doi: 10.1002/bjs.1800531109. PMID: 5331894

Prognosis

Otorkpa OJ, Otorkpa CO, Adebola OA, Anuniru C
Am J Trop Med Hyg 2024 Dec 4;111(6):1164-1165. Epub 2024 Sep 24 doi: 10.4269/ajtmh.24-0406. PMID: 39317183Free PMC Article
Behanan AG, Auluck A, Pai KL
Br J Oral Maxillofac Surg 2004 Jun;42(3):267-9. doi: 10.1016/j.bjoms.2004.02.018. PMID: 15121279
Berthold P
Dent Clin North Am 2003 Jul;47(3):559-74. doi: 10.1016/s0011-8532(03)00020-x. PMID: 12848465
Fieger A, Marck KW, Busch R, Schmidt A
Trop Med Int Health 2003 May;8(5):402-7. doi: 10.1046/j.1365-3156.2003.01036.x. PMID: 12753633
Adolph HP, Yugueros P, Woods JE
Ann Plast Surg 1996 Dec;37(6):657-68. doi: 10.1097/00000637-199612000-00017. PMID: 8988783

Clinical prediction guides

Gebretsadik HG, de Kiev LC
PLoS Negl Trop Dis 2022 Sep;16(9):e0010372. Epub 2022 Sep 13 doi: 10.1371/journal.pntd.0010372. PMID: 36099293Free PMC Article
Feller L, Khammissa RAG, Altini M, Lemmer J
Periodontol 2000 2019 Jun;80(1):189-199. doi: 10.1111/prd.12275. PMID: 31090145Free PMC Article
Huyghe A, François P, Mombelli A, Tangomo M, Girard M, Baratti-Mayer D, Bolivar I, Pittet D, Schrenzel J; Geneva Study Group on Noma
PLoS Negl Trop Dis 2013;7(9):e2453. Epub 2013 Sep 26 doi: 10.1371/journal.pntd.0002453. PMID: 24086784Free PMC Article
Bisseling P, Bruhn J, Erdsach T, Ettema AM, Sautter R, Bergé SJ
Int J Oral Maxillofac Surg 2010 Sep;39(9):873-7. Epub 2010 Jun 11 doi: 10.1016/j.ijom.2010.05.002. PMID: 20541369
Falkler WA Jr, Enwonwu CO, Idigbe EO
Oral Dis 1999 Apr;5(2):150-5. doi: 10.1111/j.1601-0825.1999.tb00081.x. PMID: 10522213

Recent systematic reviews

Eleje GU, Okoh EE, Igbodike EP, Akinsolu FT, Nwaokorie FO, Lusher JM, Tantawi ME, Salako AO, Ezechi OC, Foláyan MO
BMC Oral Health 2024 Jun 12;24(1):685. doi: 10.1186/s12903-024-04451-y. PMID: 38867180Free PMC Article
Onu JU, Aluh DO, Ononiwu CN
Trop Doct 2023 Oct;53(4):470-474. Epub 2023 May 10 doi: 10.1177/00494755231175529. PMID: 37165663
Galli A, Brugger C, Fürst T, Monnier N, Winkler MS, Steinmann P
Lancet Infect Dis 2022 Aug;22(8):e221-e230. Epub 2022 Mar 15 doi: 10.1016/S1473-3099(21)00698-8. PMID: 35303478

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...