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Lymphosarcoma Involving Spleen

MedGen UID:
102289
•Concept ID:
C0153710
•
Neoplastic Process
Synonym: Lymphosarcoma of spleen
SNOMED CT: Lymphosarcoma of spleen (188506004)

Definition

An antiquated term that refers to a non-Hodgkin lymphoma composed of small and medium sized lymphocytes affecting the spleen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLymphosarcoma Involving Spleen

Professional guidelines

PubMed

Leukemic Non-nodal Mantle Cell Lymphoma: Diagnosis and Treatment.
Jain AG, Chang CC, Ahmad S, Mori S
Curr Treat Options Oncol 2019 Nov 27;20(12):85. doi: 10.1007/s11864-019-0684-8. PMID: 31776787
Mantle cell lymphoma: 2017 update on diagnosis, risk-stratification, and clinical management.
Vose JM
Am J Hematol 2017 Aug;92(8):806-813. doi: 10.1002/ajh.24797. PMID: 28699667
Mantle cell lymphoma: 2015 update on diagnosis, risk-stratification, and clinical management.
Vose JM
Am J Hematol 2015 Aug;90(8):739-45. doi: 10.1002/ajh.24094. PMID: 26103436

Recent clinical studies

Etiology

Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
Risk-tailored treatment of splenic marginal zone lymphoma.
Castelli R, Balzarotti M, Salvi E, Simona Rossi R, Lambertenghi Deliliers G, Bergamaschini L, Gidaro A
Anticancer Drugs 2022 Jan 1;33(1):e36-e42. doi: 10.1097/CAD.0000000000001165. PMID: 34407041
Smoldering mantle cell lymphoma.
Ye H, Desai A, Zeng D, Nomie K, Romaguera J, Ahmed M, Wang ML
J Exp Clin Cancer Res 2017 Dec 15;36(1):185. doi: 10.1186/s13046-017-0652-8. PMID: 29246179Free PMC Article
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Mycosis fungoides.
Zinzani PL, Ferreri AJ, Cerroni L
Crit Rev Oncol Hematol 2008 Feb;65(2):172-82. Epub 2007 Oct 22 doi: 10.1016/j.critrevonc.2007.08.004. PMID: 17950613

Diagnosis

Extranodal T- and NK-cell lymphomas.
de Leval L, Feldman AL, Pileri S, Nakamura S, Gaulard P
Virchows Arch 2023 Jan;482(1):245-264. Epub 2022 Nov 7 doi: 10.1007/s00428-022-03434-0. PMID: 36336765Free PMC Article
Splenic marginal zone lymphoma.
Piris MA, Onaindía A, Mollejo M
Best Pract Res Clin Haematol 2017 Mar-Jun;30(1-2):56-64. Epub 2016 Nov 5 doi: 10.1016/j.beha.2016.09.005. PMID: 28288718
Primary hepatic lymphoma.
Padhan RK, Das P, Shalimar
Trop Gastroenterol 2015 Jan-Mar;36(1):14-20. doi: 10.7869/tg.239. PMID: 26591949
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Gamma-delta T-cell lymphomas.
Tripodo C, Iannitto E, Florena AM, Pucillo CE, Piccaluga PP, Franco V, Pileri SA
Nat Rev Clin Oncol 2009 Dec;6(12):707-17. Epub 2009 Nov 10 doi: 10.1038/nrclinonc.2009.169. PMID: 19901919

Therapy

PET/CT: Clinical role in lymphomas.
Papathanasiou N
Hell J Nucl Med 2023 May-Aug;26 Suppl:36-37. PMID: 37658560
Risk-tailored treatment of splenic marginal zone lymphoma.
Castelli R, Balzarotti M, Salvi E, Simona Rossi R, Lambertenghi Deliliers G, Bergamaschini L, Gidaro A
Anticancer Drugs 2022 Jan 1;33(1):e36-e42. doi: 10.1097/CAD.0000000000001165. PMID: 34407041
Splenic marginal zone lymphoma: from genetics to management.
Arcaini L, Rossi D, Paulli M
Blood 2016 Apr 28;127(17):2072-81. Epub 2016 Mar 17 doi: 10.1182/blood-2015-11-624312. PMID: 26989207
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Gamma-delta T-cell lymphomas.
Tripodo C, Iannitto E, Florena AM, Pucillo CE, Piccaluga PP, Franco V, Pileri SA
Nat Rev Clin Oncol 2009 Dec;6(12):707-17. Epub 2009 Nov 10 doi: 10.1038/nrclinonc.2009.169. PMID: 19901919

Prognosis

Smoldering mantle cell lymphoma.
Ye H, Desai A, Zeng D, Nomie K, Romaguera J, Ahmed M, Wang ML
J Exp Clin Cancer Res 2017 Dec 15;36(1):185. doi: 10.1186/s13046-017-0652-8. PMID: 29246179Free PMC Article
Primary hepatic lymphoma.
Padhan RK, Das P, Shalimar
Trop Gastroenterol 2015 Jan-Mar;36(1):14-20. doi: 10.7869/tg.239. PMID: 26591949
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Gamma-delta T-cell lymphomas.
Tripodo C, Iannitto E, Florena AM, Pucillo CE, Piccaluga PP, Franco V, Pileri SA
Nat Rev Clin Oncol 2009 Dec;6(12):707-17. Epub 2009 Nov 10 doi: 10.1038/nrclinonc.2009.169. PMID: 19901919
Mycosis fungoides.
Zinzani PL, Ferreri AJ, Cerroni L
Crit Rev Oncol Hematol 2008 Feb;65(2):172-82. Epub 2007 Oct 22 doi: 10.1016/j.critrevonc.2007.08.004. PMID: 17950613

Clinical prediction guides

PET/CT: Clinical role in lymphomas.
Papathanasiou N
Hell J Nucl Med 2023 May-Aug;26 Suppl:36-37. PMID: 37658560
Pre-treatment total metabolic tumour volumes in lymphoma: Does quantity matter?
El-Galaly TC, Villa D, Cheah CY, Gormsen LC
Br J Haematol 2022 Apr;197(2):139-155. Epub 2022 Jan 17 doi: 10.1111/bjh.18016. PMID: 35037240
Risk-tailored treatment of splenic marginal zone lymphoma.
Castelli R, Balzarotti M, Salvi E, Simona Rossi R, Lambertenghi Deliliers G, Bergamaschini L, Gidaro A
Anticancer Drugs 2022 Jan 1;33(1):e36-e42. doi: 10.1097/CAD.0000000000001165. PMID: 34407041
Smoldering mantle cell lymphoma.
Ye H, Desai A, Zeng D, Nomie K, Romaguera J, Ahmed M, Wang ML
J Exp Clin Cancer Res 2017 Dec 15;36(1):185. doi: 10.1186/s13046-017-0652-8. PMID: 29246179Free PMC Article
Mycosis fungoides.
Zinzani PL, Ferreri AJ, Cerroni L
Crit Rev Oncol Hematol 2008 Feb;65(2):172-82. Epub 2007 Oct 22 doi: 10.1016/j.critrevonc.2007.08.004. PMID: 17950613

Recent systematic reviews

Inferior survival and frequent hepatic dysfunction in non-Hodgkin's lymphoma patients with HBV infection: a systematic review and meta-analysis.
Zhang MY, Gao F, Zhao YW, Ni BW, Huang HH, Hou J
Hematology 2022 Dec;27(1):70-79. doi: 10.1080/16078454.2021.2011546. PMID: 34957924
Reappraisal of primary hepatic lymphoma: Is surgical resection underestimated?
Cesaretti M, Loustau M, Robba C, Senescende L, Zarzavadjian Le Bian A
Crit Rev Oncol Hematol 2018 Mar;123:1-6. Epub 2018 Jan 30 doi: 10.1016/j.critrevonc.2018.01.004. PMID: 29482772

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