NEXN nexilin F-actin binding protein

Gene ID: 91624, updated on 27-Nov-2024
Gene type: protein coding
Also known as: CMH20; NELIN

Summary

This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]

Associated conditions

See all available tests in GTR for this gene

Description	Tests
Dilated cardiomyopathy 1CC MedGen: C2751084OMIM: 613122GeneReviews: Dilated Cardiomyopathy Overview	See labs
Hypertrophic cardiomyopathy 20 MedGen: C3151267OMIM: 613876GeneReviews: Hypertrophic Cardiomyopathy Overview	See labs
Primary dilated cardiomyopathy MedGen: C0007193GeneReviews: Dilated Cardiomyopathy Overview	See labs

Genomic context

Location:: 1p31.1

Sequence:: Chromosome: 1; NC_000001.11 (77888624..77943895)

Total number of exons:: 13

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for NEXN variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
MedGen
Related information in MedGen
NEXN database
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants

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