ANO1 anoctamin 1
Gene ID: 55107, updated on 4-Jan-2025Gene type: protein coding
Also known as: DOG1; INDMS; MYMY7; TAOS2; ORAOV2; TMEM16A
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- Go to complete Gene record for ANO1
- Go to Variation Viewer for ANO1 variants
Summary
Enables identical protein binding activity; iodide transmembrane transporter activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including monoatomic anion transport; mucus secretion; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. Implicated in Moyamoya disease. [provided by Alliance of Genome Resources, Jan 2025]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Intestinal dysmotility syndrome | not available |
| Moyamoya disease 7 | not available |
Genomic context
- Location:
- 11q13.3
- Sequence:
- Chromosome: 11; NC_000011.10 (69965997..70189530)
- Total number of exons:
- 31
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for ANO1 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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