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GTR Home > Conditions/Phenotypes > SPERMATOGENIC FAILURE, X-LINKED, 9

SPERMATOGENIC FAILURE, X-LINKED, 9

Summary

X-linked spermatogenic failure-9 (SPGFX9) is characterized by male infertility due to nonobstructive azoospermia resulting from maturation arrest. A benign Leydig cell tumor was observed in 1 patient (Li et al., 2023). For a general phenotypic description and discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: RbAp46, SPGFX9, RBBP7
    Summary: RB binding protein 7, chromatin remodeling factor

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