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GTR Home > Conditions/Phenotypes > Alfadhel syndrome

Summary

Alfadhel syndrome (AFDL) is an autosomal recessive neurodevelopmental disorder with features of global developmental delay, hypotonia, and facial dysmorphism (Asiri et al., 2020, Bertoli-Avella et al., 2021). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: GDS1, SmgGDS, RAP1GDS1
    Summary: Rap1 GTPase-GDP dissociation stimulator 1

Clinical features

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