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Parkinson disease 25, autosomal recessive early-onset, with impaired intellectual development

Summary

Parkinson disease-25 (PARK25) is a progressive neurodegenerative disorder characterized by onset of parkinsonism in late childhood/adolescence and developmental delay/impaired intellectual development. Cognitive impairment is mild to moderate and nonprogressive (Fevga et al., 2023). For a general phenotypic description and a discussion of genetic heterogeneity of Parkinson disease, see 168600. [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: PARK25, PP2A, PPP2R4, PR53, PTPA
    Summary: protein phosphatase 2 phosphatase activator

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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