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GTR Home > Conditions/Phenotypes > Spermatogenic failure 77

Spermatogenic failure 77

Summary

Spermatogenic failure-77 (SPGF77) is characterized by male infertility due to extreme oligozoospermia or azoospermia. Nearly all spermatozoa present on semen analysis are morphologically abnormal, with amorphous, enlarged, and/or fragmented heads, and some are multiflagellated. Testicular tissue shows arrest at the round spermatid stage (Wyrwoll et al., 2022). For a general phenotypic description and a discussion of genetic heterogeneity of spermatogenic failure, see SPGF1 (258150). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: FKBP36, SPGF77, FKBP6
    Summary: FKBP prolyl isomerase family member 6 (inactive)

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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