Colorectal cancer, hereditary nonpolyposis, type 6

Synonyms: Colon cancer, hereditary nonpolyposis, type 6; Colon cancer, hereditary nonpolyposis, type 6, somatic

Summary

Any hereditary nonpolyposis colon cancer in which the cause of the disease is a mutation in the TGFBR2 gene. [from MONDO]

Available tests

46 tests are in the database for this condition.

Clinical tests (46 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

Associated genes Help
Genes reported to contribute to the condition.

TGFBR2
269 tests
Also known as: AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFR-2, TGFbeta-RII, tbetaR-II, TGFBR2
Summary: transforming growth factor beta receptor 2

Imported from Human Phenotype Ontology (HPO)

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Abnormality of the digestive system
- Hereditary nonpolyposis colorectal carcinoma
  Hereditary nonpolyposis colorectal carcinoma
  - MedGen UID: 870541
  - Concept ID: C4024989
  - Finding: Neoplastic Process
  Abnormality of the digestive system
  See: Feature record | Search on this feature

Reviews

Clinical resources

Practice guidelines

NCCN, 2024
NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Colon Cancer, 2024
NICE, 2021
UK NICE Guideline NG151, Colorectal cancer, 2021
ACMG ACT, 2019
American College of Medical Genetics and Genomics, Genomic Testing (Secondary Findings) ACT Sheet, MLH1, MSH2, MSH6, PMS2, EPCAM Pathogenic Variants, Lynch Syndrome (Hereditary Non-polyposis Colon Cancer [HNPCC]), 2019
ACMG ACT, 2012
American College of Medical Genetics and Genomics Family History ACT Sheet, Colon Cancer (Asymptomatic), 2012

Molecular resources

Consumer resources

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