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GTR Home > Conditions/Phenotypes > Spermatogenic failure, Y-linked, 2

Spermatogenic failure, Y-linked, 2

Synonyms
AZOOSPERMIA, NONOBSTRUCTIVE, Y-LINKED; OLIGOSPERMIA, NONOBSTRUCTIVE, Y-LINKED; OLIGOZOOSPERMIA, NONOBSTRUCTIVE, Y-LINKED; SPERMATOGENIC ARREST, Y-LINKED; SPERMATOGENIC FAILURE, NONOBSTRUCTIVE, Y-LINKED; Y Chromosome Infertility

Summary

Excerpted from the GeneReview: Y Chromosome Infertility
Y chromosome infertility is characterized by azoospermia (absence of sperm), severe oligozoospermia (<1 x 106 sperm/mL semen), moderate oligozoospermia (1-5 x 106 sperm/mL semen), or mild oligozoospermia (5-20 x 106 sperm/mL semen). Males with Y chromosome infertility usually have no obvious symptoms, although physical examination may reveal small testes.
Full text of GeneReview (by section):
Summary
Diagnosis
Clinical Characteristics
Genetically Related Disorders
Differential Diagnosis
Management
Genetic Counseling
Resources
Molecular Genetics
Chapter Notes
References
Authors:
Yuting Fan
Sherman J Silber
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Available tests

17 tests are in the database for this condition.

Clinical tests (17 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: BPY2A, VCY2, VCY2A, BPY2
    Summary: basic charge Y-linked 2

  • Also known as: CDY, CDY1A, CDY1
    Summary: chromodomain Y-linked 1

  • Also known as: CDY, CDY2, CDY2A
    Summary: chromodomain Y-linked 2A

  • Also known as: DAZ, SPGY, DAZ1
    Summary: deleted in azoospermia 1

  • Also known as: pDP1678, DAZ2
    Summary: deleted in azoospermia 2

  • Also known as: pDP1679, DAZ3
    Summary: deleted in azoospermia 3

  • Also known as: DBY, DDX3Y
    Summary: DEAD-box helicase 3 Y-linked

  • Also known as: HSF2L, HSFY, HSFY1
    Summary: heat shock transcription factor Y-linked 1

  • Also known as: HY, HYA, JARID1D, SMCY, KDM5D
    Summary: lysine demethylase 5D

  • Also known as: PRY1, PTPN13LY, PRY
    Summary: PTPN13 like Y-linked

  • Also known as: PTPN13LY2, PRY2
    Summary: PTPN13 like Y-linked 2

  • Also known as: RBM, RBM1, RBM2, RBMY, RBMY1C, YRRM1, YRRM2, RBMY1A1
    Summary: RNA binding motif protein Y-linked family 1 member A1

  • Also known as: RPS4Y2P, RPS4Y2
    Summary: ribosomal protein S4 Y-linked 2

  • Also known as: DFFRY, FAF-Y, SPGFY2, USP9Y
    Summary: ubiquitin specific peptidase 9 Y-linked

  • Also known as: BPY1, VCY1, VCY1A, VCY
    Summary: variable charge Y-linked

  • Also known as: XKRY1, XKRY
    Summary: XK related, Y-linked (pseudogene)

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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