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GTR Home > Conditions/Phenotypes > Reticulate acropigmentation of Kitamura

Reticulate acropigmentation of Kitamura

Synonyms
Kitamura reticulate acropigmentation; Reticular pigment anomaly of flexures
Modes of inheritance
Autosomal dominant inheritance (Orphanet)

Summary

A rare, genetic, hyperpigmentation of the skin disease characterized by childhood to adulthood-onset of reticulate, slightly depressed, sharply demarcated, brown, macular skin lesions without hypopigmentation, affecting the dorsa of the hands and feet, and, occasionally, progressing to involve limbs, neck, forehead and/or trunk. Interrupted dermatoglyphics and palmoplantar pits may be additionally observed. Histologically, hyperpigmented lesions show slightly elongated and thinned rete ridges, mild hyperkeratosis without parakeratosis and absence of incontinentia pigmenti. [from ORDO]

Available tests

11 tests are in the database for this condition.

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Clinical tests (11 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: AD10, AD18, CD156c, CDw156, HsT18717, MADM, RAK, kuz, ADAM10
    Summary: ADAM metallopeptidase domain 10

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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