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GTR Home > Conditions/Phenotypes > Mesothelioma, malignant

Mesothelioma, malignant

Synonyms
Malignant mesothelioma (disease)
Modes of inheritance
Not genetically inherited (Orphanet)

Summary

Malignant mesothelioma is an aggressive neoplasm of the serosal lining of the chest etiologically linked to asbestos. It is diagnosed in approximately 2,000 to 3,000 individuals annually in the United States, most of whom die within 2 years of diagnosis (summary by Bott et al., 2011). See also 614327 for a tumor predisposition syndrome that may contribute to the development of malignant mesothelioma upon asbestos exposure and is caused by germline mutation in the BAP1 gene (603089) on chromosome 3p21. [from OMIM]

Available tests

52 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (52 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CARMEN, CIPER, CLAP, IMD37, c-E10, mE10, BCL10
    Summary: BCL10 immune signaling adaptor

  • Also known as: AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33, WT1
    Summary: WT1 transcription factor

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

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