ProfileGDS5420 / 59433_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 63% 57% 4% 48% 51% 41% 67% 66% 62% 28% 20% 19% 39% 46% 69% 46% 21% 55% 59% 48% 34% 49% 61% 46% 59% 2% 48% 62% 47% 72% 67% 49% 40% 63% 48% 57% 45% 46% 74% 56% 31% 53% 57% 33% 40% 29% 50% 49% 27% 53% 26% 39% 52% 49% 68% 54% 36% 41% 58% 41% 69% 10% 56% 59% 38% 37% 9% 57% 43% 16% 50% 14% 37% 49% 58% 34% 58% 40% 29% 66% 63% 59% 32% 15% 49% 49% 49% 75% 47% 25% 47% 46% 28% 50% 63% 48% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose380.3263
GSM1296119B_lesional_pre-dose269.8557
GSM1296076C_lesional_pre-dose5.14
GSM1296092D_lesional_pre-dose138.948
GSM1296103E_lesional_pre-dose176.9151
GSM1296078F_lesional_pre-dose88.9541
GSM1296107G_lesional_pre-dose474.567
GSM1296109H_lesional_pre-dose469.4166
GSM1296080I_lesional_pre-dose341.3362
GSM1296090J_lesional_pre-dose38.228
GSM1296074K_lesional_pre-dose20.7720
GSM1296111L_lesional_pre-dose
GSM1296099M_lesional_pre-dose22.0419
GSM1296086O_lesional_pre-dose79.839
GSM1296117P_lesional_pre-dose145.1646
GSM1296113Q_lesional_pre-dose549.8369
GSM1296096R_lesional_pre-dose129.8846
GSM1296105S_lesional_pre-dose26.9721
GSM1296098T_lesional_pre-dose233.355
GSM1296101U_lesional_pre-dose301.7859
GSM1296121V_lesional_pre-dose155.0648
GSM1296088W_lesional_pre-dose59.3734
GSM1296082X_lesional_pre-dose146.1549
GSM1296115Y_lesional_pre-dose339.9861
GSM1296084Z_lesional_pre-dose135.9546
GSM1296072B_lesional_day8310.4259
GSM1296069L_lesional_day83.262
GSM1296071P_lesional_day8174.6648
GSM1296070Y_lesional_day8365.6162
GSM1296073V_lesional_day8139.8147
GSM1296034A_lesional_day15665.3572
GSM1296041G_lesional_day15485.5267
GSM1296035R_lesional_day15158.749
GSM1296038U_lesional_day1589.0940
GSM1296047B_lesional_day15390.163
GSM1296039E_lesional_day15147.0948
GSM1296042H_lesional_day15275.1457
GSM1296043L_lesional_day15
GSM1296037M_lesional_day15131.5945
GSM1296046P_lesional_day15151.2146
GSM1296044Q_lesional_day15717.1474
GSM1296045Y_lesional_day15265.2356
GSM1296025C_lesional_day1550.3931
GSM1296033D_lesional_day15209.5153
GSM1296027I_lesional_day15249.1757
GSM1296032J_lesional_day1557.633
GSM1296024K_lesional_day1583.4340
GSM1296031W_lesional_day1544.729
GSM1296028X_lesional_day15172.550
GSM1296029Z_lesional_day15161.349
GSM1296026F_lesional_day1540.1127
GSM1296030O_lesional_day15181.2453
GSM1296040S_lesional_day1536.6226
GSM1296036T_lesional_day1594.4139
GSM1296048V_lesional_day15197.2852
GSM1296059A_lesional_day43158.8849
GSM1296066G_lesional_day43516.6368
GSM1296060R_lesional_day43220.3254
GSM1296063U_lesional_day4372.3136
GSM1296064E_lesional_day4396.741
GSM1296067H_lesional_day43298.4958
GSM1296062M_lesional_day4398.0941
GSM1296068Q_lesional_day43553.969
GSM1296050C_lesional_day4311.4710
GSM1296057D_lesional_day43246.1156
GSM1296052I_lesional_day43284.2759
GSM1296054J_lesional_day4382.9338
GSM1296049K_lesional_day4375.537
GSM1296055W_lesional_day439.119
GSM1296053X_lesional_day43278.5557
GSM1296058Z_lesional_day43104.0443
GSM1296051F_lesional_day4318.3116
GSM1296056O_lesional_day43159.9350
GSM1296065S_lesional_day4314.5814
GSM1296061T_lesional_day4380.1337
GSM1296095A_non-lesional_pre-dose155.4749
GSM1296120B_non-lesional_pre-dose295.1858
GSM1296077C_non-lesional_pre-dose57.1734
GSM1296093D_non-lesional_pre-dose297.3758
GSM1296104E_non-lesional_pre-dose90.1140
GSM1296079F_non-lesional_pre-dose42.9229
GSM1296108G_non-lesional_pre-dose456.2866
GSM1296110H_non-lesional_pre-dose407.2863
GSM1296081I_non-lesional_pre-dose294.4459
GSM1296091J_non-lesional_pre-dose49.4132
GSM1296075K_non-lesional_pre-dose16.0215
GSM1296112L_non-lesional_pre-dose
GSM1296100M_non-lesional_pre-dose167.0649
GSM1296087O_non-lesional_pre-dose147.1749
GSM1296118P_non-lesional_pre-dose185.9749
GSM1296114Q_non-lesional_pre-dose776.1375
GSM1296097R_non-lesional_pre-dose145.9647
GSM1296106S_non-lesional_pre-dose35.4625
GSM1296102U_non-lesional_pre-dose157.5547
GSM1296122V_non-lesional_pre-dose148.6346
GSM1296089W_non-lesional_pre-dose45.6628
GSM1296083X_non-lesional_pre-dose173.9550
GSM1296116Y_non-lesional_pre-dose398.5963
GSM1296085Z_non-lesional_pre-dose154.3648