ProfileGDS5420 / 48612_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 80% 67% 69% 75% 84% 68% 66% 77% 83% 72% 74% 66% 73% 72% 66% 69% 76% 74% 81% 82% 67% 77% 72% 68% 77% 69% 61% 65% 64% 70% 82% 66% 76% 73% 67% 71% 67% 67% 77% 67% 67% 64% 73% 79% 79% 73% 75% 72% 77% 77% 72% 76% 84% 78% 67% 80% 66% 72% 70% 74% 68% 78% 64% 64% 74% 81% 77% 73% 72% 80% 79% 67% 75% 70% 81% 74% 67% 71% 78% 69% 71% 69% 69% 76% 74% 68% 67% 79% 79% 67% 72% 70% 74% 76% 66% 76% 77% 65% 75% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose1041.2880
GSM1296119B_lesional_pre-dose481.1767
GSM1296076C_lesional_pre-dose500.7769
GSM1296092D_lesional_pre-dose791.8275
GSM1296103E_lesional_pre-dose1409.1484
GSM1296078F_lesional_pre-dose468.168
GSM1296107G_lesional_pre-dose443.0166
GSM1296109H_lesional_pre-dose870.2577
GSM1296080I_lesional_pre-dose1292.4183
GSM1296090J_lesional_pre-dose661.372
GSM1296074K_lesional_pre-dose722.3574
GSM1296111L_lesional_pre-dose450.8666
GSM1296099M_lesional_pre-dose717.7373
GSM1296086O_lesional_pre-dose638.9572
GSM1296117P_lesional_pre-dose466.0366
GSM1296113Q_lesional_pre-dose530.7169
GSM1296096R_lesional_pre-dose812.476
GSM1296105S_lesional_pre-dose731.1974
GSM1296098T_lesional_pre-dose1129.4781
GSM1296101U_lesional_pre-dose1191.8682
GSM1296121V_lesional_pre-dose468.3967
GSM1296088W_lesional_pre-dose893.0977
GSM1296082X_lesional_pre-dose624.9572
GSM1296115Y_lesional_pre-dose501.1268
GSM1296084Z_lesional_pre-dose888.5677
GSM1296072B_lesional_day8546.1269
GSM1296069L_lesional_day8344.4561
GSM1296071P_lesional_day8445.3365
GSM1296070Y_lesional_day8415.0964
GSM1296073V_lesional_day8550.1470
GSM1296034A_lesional_day151170.182
GSM1296041G_lesional_day15452.8766
GSM1296035R_lesional_day15859.9976
GSM1296038U_lesional_day15674.4273
GSM1296047B_lesional_day15492.8367
GSM1296039E_lesional_day15611.9571
GSM1296042H_lesional_day15474.9467
GSM1296043L_lesional_day15493.4567
GSM1296037M_lesional_day15885.8577
GSM1296046P_lesional_day15485.9767
GSM1296044Q_lesional_day15510.3267
GSM1296045Y_lesional_day15418.5264
GSM1296025C_lesional_day15690.3573
GSM1296033D_lesional_day151019.7779
GSM1296027I_lesional_day151003.8179
GSM1296032J_lesional_day15681.8773
GSM1296024K_lesional_day15777.7375
GSM1296031W_lesional_day15678.0672
GSM1296028X_lesional_day15870.0877
GSM1296029Z_lesional_day15919.6577
GSM1296026F_lesional_day15658.172
GSM1296030O_lesional_day15857.3576
GSM1296040S_lesional_day151321.1784
GSM1296036T_lesional_day15947.1378
GSM1296048V_lesional_day15491.967
GSM1296059A_lesional_day431093.7780
GSM1296066G_lesional_day43468.8366
GSM1296060R_lesional_day43644.5972
GSM1296063U_lesional_day43557.6170
GSM1296064E_lesional_day43708.3674
GSM1296067H_lesional_day43534.9868
GSM1296062M_lesional_day43963.3878
GSM1296068Q_lesional_day43432.3564
GSM1296050C_lesional_day43397.6364
GSM1296057D_lesional_day43718.1674
GSM1296052I_lesional_day431139.0881
GSM1296054J_lesional_day43869.9677
GSM1296049K_lesional_day43674.1173
GSM1296055W_lesional_day43648.472
GSM1296053X_lesional_day431084.9780
GSM1296058Z_lesional_day431038.7879
GSM1296051F_lesional_day43461.3367
GSM1296056O_lesional_day43778.2575
GSM1296065S_lesional_day43570.2870
GSM1296061T_lesional_day431105.9881
GSM1296095A_non-lesional_pre-dose730.0574
GSM1296120B_non-lesional_pre-dose471.6167
GSM1296077C_non-lesional_pre-dose594.5871
GSM1296093D_non-lesional_pre-dose929.1578
GSM1296104E_non-lesional_pre-dose540.8669
GSM1296079F_non-lesional_pre-dose612.9371
GSM1296108G_non-lesional_pre-dose551.8869
GSM1296110H_non-lesional_pre-dose545.1269
GSM1296081I_non-lesional_pre-dose830.3676
GSM1296091J_non-lesional_pre-dose747.5874
GSM1296075K_non-lesional_pre-dose495.3168
GSM1296112L_non-lesional_pre-dose508.7667
GSM1296100M_non-lesional_pre-dose995.7279
GSM1296087O_non-lesional_pre-dose996.7579
GSM1296118P_non-lesional_pre-dose504.2867
GSM1296114Q_non-lesional_pre-dose640.272
GSM1296097R_non-lesional_pre-dose556.970
GSM1296106S_non-lesional_pre-dose742.0474
GSM1296102U_non-lesional_pre-dose820.1276
GSM1296122V_non-lesional_pre-dose451.3466
GSM1296089W_non-lesional_pre-dose834.5476
GSM1296083X_non-lesional_pre-dose912.3577
GSM1296116Y_non-lesional_pre-dose437.2765
GSM1296085Z_non-lesional_pre-dose795.0775