ProfileGDS5420 / 40837_at
TitlePsoriasis response to brodalumab: dose response and time course
OrganismHomo sapiens


lesional psoriatic skin non-lesional skin baseline 8 d 15 d 43 d baseline untreated brodalumab placebo brodalumab placebo brodalumab placebo untreated n/a 350 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a 140 mg brodalumab 350 mg brodalumab 700 mg brodalumab n/a A B C D E F G H I J K L M O P Q R S T U V W X Y Z B L P Y V A G R U B E H L M P Q Y C D I J K W X Z F O S T V A G R U E H M Q C D I J K W X Z F O S T A B C D E F G H I J K L M O P Q R S U V W X Y Z GSM1296094 GSM1296119 GSM1296076 GSM1296092 GSM1296103 GSM1296078 GSM1296107 GSM1296109 GSM1296080 GSM1296090 GSM1296074 GSM1296111 GSM1296099 GSM1296086 GSM1296117 GSM1296113 GSM1296096 GSM1296105 GSM1296098 GSM1296101 GSM1296121 GSM1296088 GSM1296082 GSM1296115 GSM1296084 GSM1296072 GSM1296069 GSM1296071 GSM1296070 GSM1296073 GSM1296034 GSM1296041 GSM1296035 GSM1296038 GSM1296047 GSM1296039 GSM1296042 GSM1296043 GSM1296037 GSM1296046 GSM1296044 GSM1296045 GSM1296025 GSM1296033 GSM1296027 GSM1296032 GSM1296024 GSM1296031 GSM1296028 GSM1296029 GSM1296026 GSM1296030 GSM1296040 GSM1296036 GSM1296048 GSM1296059 GSM1296066 GSM1296060 GSM1296063 GSM1296064 GSM1296067 GSM1296062 GSM1296068 GSM1296050 GSM1296057 GSM1296052 GSM1296054 GSM1296049 GSM1296055 GSM1296053 GSM1296058 GSM1296051 GSM1296056 GSM1296065 GSM1296061 GSM1296095 GSM1296120 GSM1296077 GSM1296093 GSM1296104 GSM1296079 GSM1296108 GSM1296110 GSM1296081 GSM1296091 GSM1296075 GSM1296112 GSM1296100 GSM1296087 GSM1296118 GSM1296114 GSM1296097 GSM1296106 GSM1296102 GSM1296122 GSM1296089 GSM1296083 GSM1296116 GSM1296085 59% 65% 54% 63% 58% 55% 60% 62% 69% 63% 52% 53% 69% 65% 56% 59% 65% 75% 67% 66% 60% 65% 58% 57% 70% 71% 58% 72% 62% 53% 80% 46% 70% 65% 72% 51% 57% 63% 87% 65% 68% 65% 74% 73% 80% 81% 77% 79% 78% 77% 65% 70% 77% 65% 62% 70% 54% 69% 60% 54% 74% 77% 71% 74% 81% 79% 77% 72% 77% 77% 79% 66% 64% 71% 64% 66% 71% 73% 83% 66% 74% 67% 70% 86% 78% 68% 68% 90% 76% 78% 69% 74% 76% 72% 72% 80% 84% 68% 84% sort by tissue sort by time sort by agent sort by dose sort by individual Gene Expression Profile
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SampleTitleValueRank
GSM1296094A_lesional_pre-dose296.7459
GSM1296119B_lesional_pre-dose413.3965
GSM1296076C_lesional_pre-dose194.9754
GSM1296092D_lesional_pre-dose364.0663
GSM1296103E_lesional_pre-dose280.9358
GSM1296078F_lesional_pre-dose208.6955
GSM1296107G_lesional_pre-dose325.9660
GSM1296109H_lesional_pre-dose377.7262
GSM1296080I_lesional_pre-dose549.5169
GSM1296090J_lesional_pre-dose355.8563
GSM1296074K_lesional_pre-dose174.1652
GSM1296111L_lesional_pre-dose213.953
GSM1296099M_lesional_pre-dose553.5669
GSM1296086O_lesional_pre-dose401.365
GSM1296117P_lesional_pre-dose264.8356
GSM1296113Q_lesional_pre-dose324.2859
GSM1296096R_lesional_pre-dose431.3265
GSM1296105S_lesional_pre-dose801.0775
GSM1296098T_lesional_pre-dose499.767
GSM1296101U_lesional_pre-dose472.5766
GSM1296121V_lesional_pre-dose314.9860
GSM1296088W_lesional_pre-dose434.5965
GSM1296082X_lesional_pre-dose251.758
GSM1296115Y_lesional_pre-dose264.2957
GSM1296084Z_lesional_pre-dose579.0170
GSM1296072B_lesional_day8592.5671
GSM1296069L_lesional_day8307.4958
GSM1296071P_lesional_day8657.2972
GSM1296070Y_lesional_day8367.5162
GSM1296073V_lesional_day8197.0653
GSM1296034A_lesional_day151063.2580
GSM1296041G_lesional_day15143.5446
GSM1296035R_lesional_day15584.6370
GSM1296038U_lesional_day15437.4365
GSM1296047B_lesional_day15650.3172
GSM1296039E_lesional_day15182.0151
GSM1296042H_lesional_day15279.457
GSM1296043L_lesional_day15396.4363
GSM1296037M_lesional_day151659.8487
GSM1296046P_lesional_day15447.1765
GSM1296044Q_lesional_day15525.2668
GSM1296045Y_lesional_day15440.1665
GSM1296025C_lesional_day15756.9274
GSM1296033D_lesional_day15703.4673
GSM1296027I_lesional_day151091.9680
GSM1296032J_lesional_day151131.6181
GSM1296024K_lesional_day15867.1477
GSM1296031W_lesional_day15974.5979
GSM1296028X_lesional_day15959.4278
GSM1296029Z_lesional_day15924.4877
GSM1296026F_lesional_day15401.565
GSM1296030O_lesional_day15581.5870
GSM1296040S_lesional_day15887.9677
GSM1296036T_lesional_day15439.165
GSM1296048V_lesional_day15351.9662
GSM1296059A_lesional_day43562.0470
GSM1296066G_lesional_day43227.4154
GSM1296060R_lesional_day43532.6569
GSM1296063U_lesional_day43321.760
GSM1296064E_lesional_day43207.6254
GSM1296067H_lesional_day43737.7374
GSM1296062M_lesional_day43914.6977
GSM1296068Q_lesional_day43631.3771
GSM1296050C_lesional_day43721.9274
GSM1296057D_lesional_day431160.0781
GSM1296052I_lesional_day431031.3179
GSM1296054J_lesional_day43910.5577
GSM1296049K_lesional_day43659.1972
GSM1296055W_lesional_day43880.1577
GSM1296053X_lesional_day43908.9977
GSM1296058Z_lesional_day431007.2379
GSM1296051F_lesional_day43447.5866
GSM1296056O_lesional_day43379.4764
GSM1296065S_lesional_day43629.5571
GSM1296061T_lesional_day43417.1364
GSM1296095A_non-lesional_pre-dose433.4966
GSM1296120B_non-lesional_pre-dose599.4871
GSM1296077C_non-lesional_pre-dose681.773
GSM1296093D_non-lesional_pre-dose1239.4483
GSM1296104E_non-lesional_pre-dose442.4766
GSM1296079F_non-lesional_pre-dose752.5274
GSM1296108G_non-lesional_pre-dose483.867
GSM1296110H_non-lesional_pre-dose587.8870
GSM1296081I_non-lesional_pre-dose1679.2886
GSM1296091J_non-lesional_pre-dose954.6278
GSM1296075K_non-lesional_pre-dose471.8568
GSM1296112L_non-lesional_pre-dose532.8968
GSM1296100M_non-lesional_pre-dose2039.4690
GSM1296087O_non-lesional_pre-dose828.0876
GSM1296118P_non-lesional_pre-dose932.378
GSM1296114Q_non-lesional_pre-dose534.469
GSM1296097R_non-lesional_pre-dose73274
GSM1296106S_non-lesional_pre-dose818.0576
GSM1296102U_non-lesional_pre-dose669.1772
GSM1296122V_non-lesional_pre-dose666.6472
GSM1296089W_non-lesional_pre-dose1077.9880
GSM1296083X_non-lesional_pre-dose1365.6984
GSM1296116Y_non-lesional_pre-dose509.6168
GSM1296085Z_non-lesional_pre-dose1361.4884